Compensation Overview

Position Summary:

Orbital Therapeutics is seeking a highly motivated, collaborative, self-driven, and creative individual to join our Immunology team. This team member will work in a fast-paced and cross-functional start-up environment with the opportunity to coordinate in vitro and preclinical studies evaluating next generation therapeutics including RNA-based vaccines and immunomodulatory drugs, while also expanding platform capabilities of Orbital’s RNA and delivery patient-focused therapeutics.

The ideal candidate will join a culture of intellectual rigor and scientific curiosity; they will be provided with ample opportunities to expand their technical skills, participate in diverse programs, and further their professional development.

Responsibilities: 

• Work as part of a team plan, execute, and troubleshoot experiments that evaluate and characterize the impact of RNA delivery, protein expression, and other project-specific immunological readouts.
• Effectively execute experiments including in vitro and ex vivo readouts and novel molecular, biochemical, and cellular biology assays including flow cytometry, ELISA/Ella, immunoblotting and other techniques.
• Optimize and culture of primary and immortalized mammalian cells using various formats and conditions.
• Isolate human PBMCs and mouse cells.
• Perform data analysis and clearly communicate findings to the immunology team and key stakeholders within the company.
• Effectively plan and organize work activities to meet team goals and company timelines.
• Maintain accurate, up-to-date documentation of experiments, protocols, and results in an electronic lab notebook and other technical reporting formats.
• Support cross-functional immunology team projects and contribute to lab organization.
• Crosstrain fellow researchers in lab-based activities.

Requirements:

• B.S. or M.S. in Immunology, Biology, Biochemistry, Molecular Biology, Bioengineering or a closely related field.
• 0-3 years of hands-on wet-lab experience in academic or industry lab setting.
• Strong molecular biology and immunology experimental skillset, including experience executing protocols, troubleshooting assays, and interest in developing new protocols.
• Hands-on experience in mammalian immortalized/primary cell culture (e.g., maintaining cell lines, transfections, preparation of cell suspensions from tissues) under strict aseptic techniques.
• Experience with flow cytometry, ELISA/Ella, immunoblotting, and molecular biology techniques.
• Familiarity conducting primary literature searches.
• Familiarity with mouse dissections and tissue processing preferred. 
• Scientifically rigorous and dependable team player with excellent written and oral communication and presentation skills.
• Detail-oriented and meticulous in experimental planning and electronic lab notebook documentation.