Associate Medical Director
Clinical Development
Updated on 5/10/2023
Cambridge, MA, USA
Experience Level
Desired Skills
  • M.D. or equivalent degree, preferably M.D.-PhD
  • Minimum 3+ years industry or equivalent academic experience, either overseeing clinical trials or performing relevant research
  • Track record of scientific and medical excellence
  • Rigorous understanding of core scientific concepts in gene therapy, genetics and immunology
  • Specialization in Hematology, Neurology or Hepatology preferred, but not required. Broad medical knowledge and facility with novel medical concepts is required
  • Basic understanding of Good Clinical Practice
  • Facility and comfort with standard statistical methodologies and analytical tools
  • Strong communication skills, with demonstrated experience composing scientific publications and delivering oral presentations
  • Ability to work in a heavily matrixed, cross-functional environment
  • In collaboration with research, clinical sciences, regulatory affairs and clinical operations, develop a clinical trials strategy for the efficient and safe introduction of Prime gene editing therapeutics into human study participants, through in-human proof-of-concept
  • With support from clinical sciences and medical writing, conceptualize and author clinical trials protocols, including observational and all interventional trials from phase I - IV
  • Serve as medical monitor, responsible for interfacing with site investigators, overseeing patient safety and analyzing data from clinical trials
  • Represent clinical development on cross functional program teams
  • Organize Scientific Advisory Boards and solicit feedback from Key Opinion Leaders
  • Support Prime Medicine regulatory interactions both in the formulation of regulatory documents and in face-to-face discussions with regulators
  • Collaborate with pre-clinical research to implement a translational biomarkers program for all clinical trials, and analyze translational data from Prime Medicine's trials
  • Attend scientific and medical conferences as needed, to support presentation of Prime Medicine data and/or acquire state-of-the-art information in a relevant therapeutic field
  • Travel to investigator sites, regulatory meetings and conferences will be required
Prime Medicine

51-200 employees

Gene editing biotechnology company
Company Overview
Prime Medicine's mission is to transform the lives of patients with debilitating diseases through the application of our groundbreaking Prime Editing platform and technology. The company uses Prime Editing, a next-generation gene editing approach that they believe can address the genetic cause of disease and potentially provide patients with long-lasting cures.