Full-Time

Senior / Staff AI Software Engineer

Posted on 10/31/2025

Aegis Ventures

Aegis Ventures

11-50 employees

Launches AI-driven health tech companies

Compensation Overview

$185k - $280k/yr

+ Bonus + Equity

Remote in USA

Remote

Category
Software Engineering (2)
,
Required Skills
LLM
FastAPI
Python
Apache Kafka
Postgres
GraphQL
Docker
RAG
Microservices
AWS
LangChain
Databricks
Requirements
  • 7+ years of backend development experience in production environments, specifically strong Python skills, including async programming and type hints.
  • Experience building and monitoring production-quality ML and AI systems.
  • Hands-on expertise with RAG frameworks and agentic workflows.
  • Solid understanding of PostgreSQL database design and optimization.
  • Familiarity with Docker and containerization.
  • Strong testing practices using pytest.
  • Experience with microservice architectures is preferred.
  • Experience with GraphQL APIs.
  • Experience with event-driven systems and message queues.
  • Experience with major cloud providers (e.g., AWS).
  • Shipped production LLM systems: ideally RAG architectures, agent/tool use, and prompt/system design, with LangChain (tracing/evals via LangSmith), embeddings, and vector databases (Databricks Vector Search preferred). Deep expertise in retrieval quality, including chunking, metadata, hybrid search, reranking, and grounding.
Responsibilities
  • Design and develop robust, scalable, event-driven services using Python, FastAPI, Apache Kafka and GraphQL.
  • Build fundamental LLM agents and integrate them into our product.
  • Work with DevOps on deployments, monitoring, and reliability improvements.
  • Maintain and optimize PostgreSQL databases and data models.
  • Collaborate across product and engineering teams to define requirements and architect features.
  • Drive engineering best practices through code reviews and mentorship.
  • Engage with current and prospective clients to drive understanding of the Caregentic AI architecture and capabilities.
  • Design, build, and operate LLM services, including RAG systems (LangChain), agentic workflows, and evaluation pipelines (LangSmith, deepeval, A/B testing).
  • Own vector search & embeddings pipelines from schema and metadata design to model benchmarking, cost/latency optimization, and Databricks Vector Search integration.
  • Lead conversational AI development enhancing NLU policies, safety guardrails, and custom action servers, plus integrating assistants with microservices.
Desired Qualifications
  • Experience with Strawberry GraphQL.
  • Experience with Kafka, Procrastinate, or similar background job systems.
  • Experience Apollo Federation or multi-service GraphQL experience.
  • Healthcare or regulated industry experience (HIPAA, HL7, FHIR).
  • Experience with Terraform or infrastructure-as-code.
  • Experience with Kubernetes.
  • Experience mentoring engineers or leading technical projects.
  • Experience working with LangSmith tracing, AWS Bedrock, LangChain runnables.
  • Experience maintaining forked open source repositories.
  • Experience with managing conversation states in conversational agents - experience with LangGraph or similar.

Aegis Ventures is a startup studio that partners with entrepreneurs and industry leaders to originate, launch, and scale new companies focused on AI and health tech. It operates a platform that combines market-shaping ideas, permanent growth capital, and ambitious people to identify opportunities, fund them long-term, and provide hands-on operational support. Unlike traditional funds, it creates companies in-house with a built-in path to rapid growth, with a strong emphasis on transforming healthcare quality, access, and cost. Its goal is to build companies capable of vast impact by using technology to improve health outcomes and societal wellbeing.

Company Size

11-50

Company Stage

N/A

Total Funding

$33.1M

Headquarters

New York City, New York

Founded

2020

Simplify Jobs

Simplify's Take

What believers are saying

  • John Noseworthy, ex-Mayo CEO, leads Caire virtual care as Executive Chairman.
  • John Driscoll and Cris Ross join as Venture Partners to scale healthtech launches.
  • Ascertain collaboration launches Optain with $12M seed for preventive AI care.

What critics are saying

  • Northwell internalizes Caire, Optain, Upliv, stripping Aegis equity in 6-12 months.
  • Optain's Eyetelligence tech faces FDA rejection due to lacking US validation in 12-18 months.
  • Wavelet's abdominal EEG fails pivotal trials against invasive standards in 18-24 months.

What makes Aegis Ventures unique

  • Aegis launches AI-powered fetal brain monitoring via Wavelet with Yale tech.
  • Aegis partners with Northwell to originate Optain for retinal AI disease detection.
  • Aegis builds healthtech ecosystem across five areas, compressing time-to-market.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Flexible Work Hours

Company Equity

Wellness Program

Mental Health Support

Company News

Yahoo Finance
Apr 14th, 2026
Yale-born fetal brain monitoring startup Wavelet secures $7M to prevent birth injuries

Wavelet Medical has secured $7 million in seed funding from Aegis Ventures to commercialise the first non-invasive, AI-powered fetal electroencephalography monitoring platform. The technology, developed at Yale, aims to detect fetal brain distress in real time and prevent avoidable brain injury at birth. Founded by Liz Golden, Dr Emily Lee and Dr Jose Cortes-Briones, Wavelet uses EEG captured through the mother's abdomen and reconstructed with AI algorithms to identify neurological distress, addressing limitations of traditional fetal heart rate monitoring, which is indeterminate in up to 85% of births. The platform targets a significant problem: over 35,000 infants suffer birth-related brain injuries annually in the US alone. Wavelet's partnership with Aegis Ventures will accelerate product development, clinical adoption and commercialisation of the technology.

Teknovation.biz
Nov 25th, 2024
News & Notes | Foundersforge Joins Village Capital’S Resource Iii Program For Entrepreneur Support Organizations

From Knoxville: The Knoxville Technology Council is asking local business representatives to complete its latest KTech Pulse 2024 Survey. Noting that the organization wants to get the pulse of Knoxville-area... The post News Notes | FoundersForge joins Village Capitals Resource III Program for Entrepreneur Support Organizations appeared first on Teknovation.biz.

Aegis Ventures
Oct 10th, 2023
Our Focus

We are driven by the mission to build companies that solve society's greatest problems, informed by the belief that the nexus of profits and purpose will create a virtuous cycle of impact that moves the world forward.

PR Newswire
Aug 22nd, 2023
Ascertain Announces Leadership Team With Appointment Of Ceo Mark Michalski, M.D. And Executive Chairman Gregg Fergus

Michalski, an Amazon alum, and Fergus, ex-CEO of 4Catalyzer, will lead the company creation platform building AI applications in healthcare.NEW YORK, Aug. 22, 2023 /PRNewswire/ -- Ascertain, a healthcare AI company creation platform, today announced the formation of its leadership team with the appointment of CEO Mark Michalski, M.D. and Executive Chairman, Gregg Fergus. Michalski and Fergus will lead Ascertain in its mission to merge deep technical, operational, and clinical expertise to deliver high-quality, equitable, and affordable healthcare.Michalski brings two decades of executive leadership experience to Ascertain. Prior to Ascertain, Michalski led strategic development for healthcare and life sciences at Amazon, was Founding Executive Director at Mass General Brigham/Harvard's Center for Clinical Data Science, and served as President and CMO of two publicly traded companies - Butterfly Network and Hyperfine Research. He is a board-certified radiologist and completed his medical training at Yale and Stanford.Fergus and Michalski met and collaborated closely at the venture studio 4Catalyzer where Fergus was CEO, launching several leading healthcare companies including Butterfly Network, Hyperfine Research, AI Therapeutics, and Quantum Si

PR Newswire
Jun 14th, 2023
Aegis Ventures And Northwell Holdings Tap Former Mayo Ceo As Executive Chairman Of Virtual Care Platform, Caire

John Noseworthy takes on key leadership role in next-generation virtual care platform, with health systems at the centerNEW YORK, June 14, 2023 /PRNewswire/ -- Caire, an innovative virtual care ecosystem created by Northwell Holdings and venture studio Aegis Ventures, today announced John Noseworthy, M.D. as Executive Chairman. Noseworthy, the emeritus president and CEO of Mayo Clinic, will lead the Caire Collaborative, a consortium of health systems that serve as investors, early adopters, and clinical partners for Caire's hybrid model of in-person and virtual care. Noseworthy will also serve on Caire's board of directors.Spearheaded by Northwell Health's president and CEO, Michael Dowling, Caire partners with health systems nationwide to redefine how care is delivered. As providers of care and as employers, health systems are uniquely positioned to better identify gaps in care and help build the solutions that address them. Caire, powered by a common operating system for AI-enabled virtual care products, will match patients with the health services they need, when they need it.Caire was founded to address critical issues facing employers today, including providing affordable, accessible, evidenced-based care that can be delivered efficiently, and supporting a patient's longitudinal care journey

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