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Full-Time

Production Manager

Primary Assembly

Posted on 10/24/2024

Elegen

Elegen

51-200 employees

Custom DNA synthesis for biotech applications

Biotechnology
Healthcare

Compensation Overview

$120k - $145kAnnually

+ Bonus + Equity + Benefits

Senior

San Carlos, CA, USA

Category
Genomics
Biology Lab & Research
Biology & Biotech
Requirements
  • Bachelor's degree in a relevant field (such as Molecular Biology, Biotechnology, or a related discipline), 5+ years of industry experience
  • 2+ years of experience lead production or manufacturing role in life sciences
  • Strong knowledge and working experience in cloning and gene synthesis processes
  • Strong knowledge and working experience of different liquid handlers like Bravo, Tecan, Hamilton, Mutliflow etc
  • Proven ability to manage production batches and personnel schedules effectively
  • Support lab execution on a daily basis
  • Experience in forecasting and maintaining KPIs
  • Excellent collaboration and communication skills to work effectively with cross-functional teams
  • Experience with new product implementation, operational scaling, and training operators
  • Strong problem-solving and troubleshooting skills
  • Availability to provide support over the weekend as needed
  • Basic bioinformatics and coding experience for data management
  • Experience with operation, maintenance, and troubleshooting of liquid handling robots, PCR, general molecular biology tools and NGS library prep devices
  • Experience in start up environments-ability to anticipate and adapt changes and maintain orders
  • Previous experience in managing a team is preferred
Responsibilities
  • Lead and Manage Primary Assembly Process: Provide technical expertise and support to the existing assembly process, ensuring its smooth operation. Identify areas for improvement and implement strategies to enhance its robustness and reliability.
  • Timely Manufacturing: Manage and execute batch and personnel schedules to ensure the timely manufacturing of the gene synthesis process. Participate in the day-to-day hands on work. Coordinate with relevant teams to optimize efficiency and meet production targets. Assist in downstream hand off for product readiness.
  • Forecasting and KPIs: Assist in forecasting production needs and maintain Key Performance Indicators (KPIs) related to production volume, quality, and efficiency. Analyze data and identify opportunities for improvement.
  • Collaboration: Collaborate closely with the Product Development and Continuous Improvements (PDI) and Research and Development (RD) teams to drive process improvements. Share insights and contribute to the development of new methods or technologies. Participate in new technology transfer activities to enhance the existing workflows.
  • Team Management: Manage a small team of production associates, providing guidance, training, and support as needed. Ensure effective communication, teamwork, and adherence to safety and quality standards.
  • Automation Support: Partner with the Automation Team to manage our instruments and provide feedback for further enhancements to our processes.
  • Troubleshooting and Weekend Support: Provide troubleshooting assistance to address any production issues that may arise. Additionally, offer on-call support over the weekend for escalations to maintain production continuity by resolving urgent matters.

Elegen focuses on improving the process of manufacturing synthetic DNA to meet the needs of the bioeconomy. The company provides custom DNA synthesis services to researchers, biotech companies, and pharmaceutical firms that require high-quality synthetic DNA for various applications, including biomanufacturing and mRNA-based treatments. Elegen's services are characterized by fast turnaround times and high accuracy, which are essential for clients' research and development. Unlike traditional DNA manufacturing methods, Elegen's approach reduces time and costs while enabling the production of valuable biologics and therapeutics. The company's goal is to support advancements in synthetic biology and biomanufacturing, particularly in the development of mRNA medicines and other advanced therapeutics.

Company Stage

Seed

Total Funding

$42.9M

Headquarters

San Carlos, California

Founded

2017

Growth & Insights
Headcount

6 month growth

30%

1 year growth

46%

2 year growth

129%
Simplify Jobs

Simplify's Take

What believers are saying

  • The recent $35M Series B funding, led by prominent investors like Triatomic Capital and GSK, will accelerate the expansion of Elegen’s ENFINIA™ DNA product line and enhance its clinical manufacturing capabilities.
  • Elegen's collaboration and licensing agreement with GSK to use their proprietary cell-free DNA manufacturing technology in developing vaccines and medicines highlights the company's potential for significant industry impact.
  • The commercial launch of the enhanced ENFINIA™ DNA, which offers highly complex DNA in as fast as 10 business days, positions Elegen as a leader in rapid and reliable DNA synthesis.

What critics are saying

  • The synthetic biology market is highly competitive, requiring Elegen to continuously innovate to maintain its edge.
  • Dependence on key partnerships, such as with GSK, could pose risks if these relationships were to change or dissolve.

What makes Elegen unique

  • Elegen's cell-free DNA manufacturing technology offers a significant advantage over traditional plasmid-based methods, reducing contamination risks and accelerating production timelines.
  • The company's ENFINIA™ DNA product line provides highly complex, NGS-verified DNA with rapid turnaround times, setting a new industry standard.
  • Elegen's Early Access Program fosters strong client relationships and provides an additional revenue stream by offering early access to their latest DNA breakthroughs.

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