Full-Time

Research Associate-Structural Biologist

University of Texas at Austin

University of Texas at Austin

No salary listed

Company Does Not Provide H1B Sponsorship

Austin, TX, USA

In Person

Category
Biology & Biotech (2)
,
Required Skills
Biochemistry
Requirements
  • Ph.D. in structural biology and/or biochemistry with demonstrated productivity in these areas.
  • Relevant education and experience may be substituted as appropriate.
Responsibilities
  • Express, purify, and characterize full-length and deletion constructs of group II intron and other non-LTR retroelement reverse transcriptase and related proteins for structural analysis and biotechnological applications using Fast Protein Liquid Chromatography FPLC and other methods.
  • Characterize wild-type and mutant proteins biochemically via enzymatic assays and determine conditions for obtaining diffraction quality crystals and/or for cryo-electron microscopy analysis of proteins and protein/nucleic acid complexes.
  • Carry out biochemical and biophysical assays.
  • Obtain structures of reverse transcriptase and related enzymes and their nucleic acid-protein complexes by X-ray diffraction and/or cryo-EM structures.
  • Write manuscripts and assist in the preparation of reports, abstracts, manuscripts and proposals.
  • Make presentations at lab meetings.
  • Attend lab meetings and other meetings.
  • Order chemicals and supplies specific to current project.
  • Provide instruction, assistance and mentoring to graduate students.
Desired Qualifications
  • Ph.D. in structural biology and/or biochemistry with at least five years’ experience and demonstrated research productivity on enzymes that bind nucleic acids and/or protein-nucleic acid complexes
University of Texas at Austin

University of Texas at Austin

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