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In Vitro Associate Principal Scientist/Pharmacology
Confirmed live in the last 24 hours
San Bruno, CA, USA
Experience Level
  • PhD + 8+ years (can include postdoc experience), in pharmacology, or related discipline (must have a minimum of 2+ years industry leading early discovery projects to IND, functional lead experience acceptable)
  • Proficient in experimental biological techniques such as immunoassays (ELISA, MSD, Luminex), qPCR, biochemical assays, enzyme kinetics, Western Blot, RNA extractions, etc
  • Working knowledge of cell cultures, including mammalian cell culture
  • Compound screening experience
  • Developed novel complex model systems (didn't just purchase off the shelf)
  • Lead the in-vitro pharmacology team, working across programs to enable characterization and screening of new compounds
  • Develop and execute in vitro assays to validate compound activity using cell-free and cell-based models
  • Perform cell cultures and mainteneance of cell lines to be used to evaluate small molecules in high and medium throughput assays
  • Perform assays to enable chemistry SAR iterations
  • Screen and test libraries of small molecules in both internal assays and with CROs
  • Mange CRO relationships to support high-throughput screens
  • Accurate and organized data entry, analysis, technical report writing, and presentation of experimental results to research groupsIdentification of best model / troubleshooting / leading projects
  • Select and champion complex, yet robust in vitro model systems for target biology
  • Manage a direct report to enable high and medium throughput screens to support all drug discovery programs
Desired Qualifications
  • Experience with neuroscience is a plus
  • Transcriptomics (RNA extractions, library prep), experience with NGS is a plus
Verge Genomics

11-50 employees

AI drug discovery biotech company
Company Overview
Verge Genomics is on a mission to develop better drugs, faster using technology. The company has built an end-to-end technology-driven drug discovery platform centered around one of the field’s largest human genomics databases in neuroscience.
  • Excellent medical, dental, and vision coverage
  • 401(k) plan with employer matching for contributions
  • Disability insurance, Life insurance, Dependant Care FSA and Healthcare FSA
  • Unlimited paid time off
  • Paid parental leave
  • Access to free onsite fitness center
  • Free snacks and lunch for employees who work onsite
  • WFH stipend for employees who work remotely
Company Core Values
  • We commit to embracing courageous ambition
  • We commit to treating every situation as an opportunity to improve
  • We commit to revealing our authentic truths (facts, feelings, things I imagine) to each other