Postdoctoral Associate

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The Desai Sethi Urology Institute at the University of Miami Miller School of Medicine is seeking to recruit a Postdoctoral Associate to lead the development and implementation of Mass Spectrometry applications for translational and clinical research. The postdoc will partner with principal investigators and an outstanding clinical urology team with the goal of defining the underlying biochemical and clinical behavior genitourinary disorders to identify new strategies that will lead to durable clinical benefits. This position will provide a unique and multidisciplinary exposure to tumor metabolism, molecular oncology, drug development, and clinical trials. The Postdoctoral Associate performs scientific research and studies under the supervision of managing staff. Moreover, the Post Doctoral Associate promotes institutional recognition through literal contributions to the scientific community.

Please submit a cover letter with your online application.

Department Specific Functions

Our laboratory focuses on mechanistic discovery to understand the metabolic and molecular mechanisms of androgen synthesis and androgen receptor gain-of-function that lead to resistance to hormonal therapy.  Our work is revealing fundamental endocrine mechanisms in both normal physiology and disease, including stress, aging, and glucocorticoid resistance, that will lead to broad applications to oncology and cancer physiology.

Specific areas include:

• Metabolic and genetic changes required for hormone therapy resistance in prostate and breast cancers

• Discovery of entirely new mechanisms of endocrine physiology and regulation

• Clinical validation in patients and clinical trials using innovative approaches

• Animal models of advanced cancer for translational and therapeutic studies

• Identifying targets for the development of new pharmacologic therapies

• Drug discovery for new therapies

The Desai Sethi Urology Institute at the University of Miami Miller School of Medicine is seeking to recruit a postdoctoral associate to lead the development and implementation of Mass Spectrometry applications for translational and clinical research. The postdoc will partner with principal investigators and an outstanding clinical urology team with the goal of defining the underlying biochemical and clinical behavior genitourinary disorders to identify new strategies that will lead to durable clinical benefits. This position will provide a unique and multidisciplinary exposure to tumor metabolism, molecular oncology, drug development, and clinical trials. 

Department Specific Qualifications                                                                                     

Ability to lead MS based projects with minimal oversight. Proficient in basic statistical methods and design of MSI / LC-MS experiments and techniques. 3+ years of relevant experience in a research or laboratory environment including: Working knowledge of MSI / LC/MS instrumentation, operation, maintenance, and troubleshooting (Experience with AB Sciex/Agilent Systems Preferred). Hands-on experience with sample preparation and extraction of small molecules from various biological matrices. Knowledge of various extraction protocols (protein precipitation, liquid-liquid extraction, solid phase extraction, etc.). Hands-on experience with different chromatographic separation and mass spectrometry methodologies for analysis of biomarkers, or small molecules.

Education:

• Ph.D. in biochemistry, chemistry, molecular biology or another relevant field required

Knowledge, Skills and Attitudes:

• Has the appropriate expertise in discovery of molecular, biochemical or chemical mechanisms; and is highly driven.

• Outstanding verbal and communication skills are required.

• Skill in collecting, organizing, and analyzing data.

• Ability to recognize, analyze, and solve a variety of problems.

• Ability to exercise sound judgment in making critical decisions.

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.

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