Full-Time

Director of Data Solutions

Axle

Axle

201-500 employees

Translational research informatics and data science

Compensation Overview

$170k - $210k/yr

North Bethesda, MD, USA

In Person

Category
Data & Analytics (2)
,
Required Skills
MLOps
Data Science
Machine Learning
ETL
RAG
Observability

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Requirements
  • 6+ years in data science, ML engineering, data platform engineering, applied research engineering, or closely related fields
  • 3+ years leading multi-disciplinary teams
  • Demonstrated success delivering production data/AI platforms (not only analyses), including architecture, delivery planning, and operational ownership
  • Strong familiarity with modern data stacks and cloud delivery (distributed compute, ETL/ELT, data quality tooling, MLOps/LLMOps concepts)
  • Ability to translate ambiguous stakeholder needs into shipped products and measurable outcomes
  • Strong people leadership: recruiting, coaching, performance management, org design
  • Comfort operating in regulated and high-governance environments (privacy, compliance, access control)
Responsibilities
  • Define reference architectures and technical standards for data/AI platforms (security, scalability, reliability, cost governance, developer experience)
  • Own platform modernization plans and technical debt reduction sequencing
  • Make build/buy/partner decisions and establish patterns that can be reused across programs
  • Lead delivery of repeatable ingestion and transformation pipelines with testing, validation, and change control
  • Own harmonization capabilities (terminology translation, unit normalization, episode building) as production services with documentation and quality dashboards
  • Partner with governance and stakeholders to define “minimum acceptable quality” and publish transparent quality measures
  • Lead delivery of production AI/ML solutions (NLP, CV, predictive models, representation learning) and deploy them with evaluation and monitoring
  • Own GenAI patterns and platforms (RAG, agentic workflows, human-in-the-loop review, traceability, privacy safeguards) as reusable services
  • Establish model lifecycle governance: approvals, audits (as needed), drift monitoring, incident response, and continuous improvement
  • Build reusable “engines” for RWE execution: cohorting/phenotyping pipelines, reproducible protocol templates, causal inference/target trial tooling patterns, and integration templates for multiple data sources
  • Staff and support analysis pods for time-sensitive, high-stakes deliverables with rigorous QC and reproducibility practices
  • Define the modeling/simulation practice charter: scope, service model, standards, compute strategy (HPC/cloud), and hiring/partnering plan
  • Lead simulation/modeling teams directly or via domain SMEs; ensure reproducible workflows and high quality bars
  • Identify and prioritize high-value hybrid ML+simulation opportunities
  • Partner with security/privacy to implement strong access controls, auditability, and (where needed) privacy-preserving approaches
  • Establish operational excellence: release management, observability, on-call/incident processes (as appropriate), and runbooks
  • Hire, grow, and retain a high-performing organization; create clear roles, career paths, and performance expectations
  • Build a culture of “research-grade rigor + production-grade discipline,” emphasizing accountability, documentation, and sustainability
Desired Qualifications
  • Healthcare data platform experience, especially interoperability/harmonization at scale (OMOP/FHIR/PCORNet/CDISC) and clinical terminology systems
  • Experience shipping GenAI solutions with governance (PII handling, traceability, human review, evaluation, monitoring)
  • Experience with privacy-preserving ML patterns (federated learning/inference) and/or sensitive data platforms
  • Experience leading simulation/modeling initiatives (scientific computing, HPC workflows, domain simulations) and partnering effectively with scientific SMEs
  • Track record of publications, open-source leadership, or scientific impact

Axle Informatics provides specialized informatics solutions for translational research, health informatics, and data science to biomedical research centers and healthcare organizations. Its offerings are customized software and data management platforms that help researchers collect, integrate, analyze, and visualize large research datasets, with end-to-end tools that automate data aggregation and deliver analytics, dashboards, and decision-support features. The company differentiates itself with an integrated, scientifically informed approach that bridges data science with application development, specifically focused on translational research and clinical data work rather than generic software. Axle’s goal is to advance public health by moving biomedical discoveries from the lab to bedside, improving healthcare outcomes.

Company Size

201-500

Company Stage

N/A

Total Funding

N/A

Headquarters

Rockville, Maryland

Founded

2002

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Simplify Jobs

Simplify's Take

What believers are saying

  • NIH awarded Axle the $11.2 million N3C Dynamic Workspaces task order on September 30, 2025.
  • NCATS extended Axle through June 27, 2026, signaling trust during transition risk.
  • SK pharmteco partnered with Axle and NIH on rare-disease gene therapy programs on May 7, 2026.

What critics are saying

  • Axle depends heavily on NIH funding; one recompete failure hits revenues by 2027.
  • NCATS limited-source notices in 2025-2026 show mission-critical work gets rebid fast.
  • A larger integrator like Dovel or Leidos can underprice Axle and compress margins.

What makes Axle unique

  • Axle embeds inside NIH, winning NCATS and NIAID support work in 2025-2026.
  • Its translational-research niche blends biomedical science, software engineering, and federal program management.
  • Repeated sole-source extensions show NIH treats Axle as operational infrastructure, not a commodity vendor.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Vacation

Paid Holidays

401(k) Company Match

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

Company News

TheGWW.com
Jul 25th, 2023
“Octo awarded $64.7M IT Infrastructure Call Order to support NCI’s Cancer research”

Octo, in partnership with Unissant, Axle Informatics, and TRex, has been awarded an IT Infrastructure and Operations Call Order to support the NCI’s OCIO.

GlobeNewswire
Jan 12th, 2023
Digital Pathology Market Worth $1.86 Billion by 2030 -

For instance, in May 2020, Indica Labs (U.S.), a provider of digital pathology solutions, collaborated with information technology consulting companies, Octo (U.S.) and Axle Informatics (U.S.) and the National Institutes of Health (NIH) (U.S.), to develop an online collection of high-resolution histopathology images of tissues from COVID-19 patients using Indica’s HALO Link platform.