Research Scientist

From target to the clinic. AbCellera’s platform integrates biology, computation, and engineering to develop impactful antibody-based medicines. We’re scientists, engineers, and business professionals who work together to turn scientific insights into breakthrough medicines. We pursue truth and scientific rigor. We think independently, act with conviction, and have the courage to work at the edge of the unknown. We offer the opportunity to stretch and explore, and to work on things that matter.

We are seeking a highly motivated Research Scientist to implement in-silico structural tools and processes in the areas of protein and antibody engineering. You will interact with a diverse team, liaising between software engineers, wet-lab scientists, bioinformaticians and data scientists, in a fast-paced environment. You are someone who is able to multitask, problem-solve, think critically, and demonstrate scientific rigor, and above all, you are someone who can learn and grow with us.

This is an exciting opportunity to join one of Canada’s most innovative biotech companies and to contribute to our cutting-edge research, driving the discovery of novel monoclonal antibodies for therapeutic use.

How you might spend your days:

• Designing, implementing, and evaluating in-silico protein engineering activities in support of a developing platform for antibody reformatting processes and optimization of therapeutic assets
• Collaborating with teams across the company to understand engineering challenges and propose solutions
• Preparing and authoring materials to educate colleagues, and communicate strategies, key findings, and implications
• Organizing, supporting, and collaborating with other team members to meet project deliverables and timelines

We’d love to hear from you if:

• You are a collaborative team player that can contribute to the design, execution, and evaluation of in-silico protein engineering workflows
• You are excited about the opportunity to integrate high throughput protein engineering methods with in-silico tools to solve real-world drug discovery problems
• You are enthusiastic about applying your expertise in protein engineering to improve the speed and quality of protein biotherapeutics development
• You are strongly self-motivated and work independently to identify project needs and follow that up with building and implementing solutions
• You have a PhD in Biochemistry, Biophysics, Structural Biology, Computational Biology, Computer Science, or a related field, or a MSc with 5+ years of related experience in a biological research setting
• You have excellent programming skills in Python, as well as a comprehensive understanding of techniques to perform in-silico protein structure design using tools such as Rosetta software suite
• You have working knowledge of antibody structure and function, and familiarity with techniques applicable to the molecular design, engineering, and experimental evaluation of antibody and/or antigen libraries for protein engineering purposes
• You have awareness of experimental analytic and biophysics techniques used for antibody characterization, e.g. size exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), capillary electrophoresis (CE), light scattering (DLS, MALS), differential scanning calorimetry (DSC), isoelectric focusing (IEF), surface plasmon resonance (SPR), etc.

What we offer:

AbCellera’s hiring range for this role is CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. 

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera.

About AbCellera:

AbCellera is a global company focused on delivering breakthrough medicines that alleviate suffering, extend lives, and improve health. Our platform includes fully integrated capabilities to create first-in-class and best-in-class antibody medicines, from discovery to clinical manufacturing. 

We are using our technological advantage to develop programs across multiple indications including endocrine and metabolic conditions, oncology, and inflammation and autoimmunity. We’re advancing programs involving complex transmembrane proteins, bispecifics, and antibody drug conjugates. 

Creating medicines is the most important work we can do. When tenacious people share a vision and work together, they can truly have a positive impact. That’s why we hire for character and intelligence, not just for CVs or experience. 

We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.

To apply:

Please submit your application through our website and refer to Job ID 23231 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.

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