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Full-Time

Principal Scientist

Biology

Confirmed live in the last 24 hours

Manifold Bio

Manifold Bio

11-50 employees

Designs precision biologics using in vivo methods

Biotechnology
Healthcare

Expert

Boston, MA, USA

Category
Biology Lab & Research
Biology & Biotech
Requirements
  • PhD or equivalent experience in neuroscience and/or molecular biology, biological engineering or a related field
  • 10+ years of hands-on wet-lab experience, including 3+ years of startup/ biotech/pharma experience
  • Experience going end-to-end from experimental design through execution and data interpretation
  • Experience developing cell-based assays
Responsibilities
  • Design, execute, interpret, and iterate on cellular and biophysical assays to evaluate lead molecule activity and mechanism of action
  • Help nominate a data-driven lead molecule selection funnel
  • Conduct hypothesis-driven investigation of mechanism of action of lead molecules
  • Serve as in vitro pharmacology/toxicology lead expert for DC nomination and IND-enabling studies
  • Drive external work with CROs as needed
  • Provide expertise on late-breaking advances in neuroscience and neurodegenerative diseases

Manifold Bio specializes in creating precision biologics for the pharmaceutical industry, focusing on drug design and development. Their main product is an in vivo drug design platform, which allows for testing drugs within living organisms rather than in laboratory settings. This platform utilizes mCodes™ technology, a unique protein barcoding system that enables the simultaneous study of multiple proteins in one experiment, making it particularly effective for complex biologics. Unlike other companies, Manifold Bio's approach to in vivo testing is the first of its kind, setting them apart in the market. The company's goal is to expand their platform and collaborate with other pharmaceutical companies to develop new therapeutics, leveraging their innovative technology to meet the growing demand for advanced drug solutions.

Company Stage

Series A

Total Funding

$45.4M

Headquarters

Boston, Massachusetts

Founded

2020

Growth & Insights
Headcount

6 month growth

2%

1 year growth

7%

2 year growth

82%
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Simplify's Take

What believers are saying

  • The significant Series A funding provides ample resources for expanding their in vivo biologics design platform, potentially accelerating growth and innovation.
  • Manifold Bio's technology could revolutionize the drug discovery process by overcoming the bottleneck of in vivo testing, making it more efficient and cost-effective.
  • Partnerships and collaborations with other pharmaceutical companies could lead to lucrative licensing deals and revenue streams.

What critics are saying

  • The highly specialized nature of their technology may limit their market to a niche segment within the pharmaceutical industry.
  • Dependence on successful integration and performance of their mCodes™ technology in real-world applications could pose a risk if the technology does not meet expectations.

What makes Manifold Bio unique

  • Manifold Bio's in vivo drug design platform, powered by their proprietary mCodes™ technology, allows for simultaneous testing of multiple proteins in a single experiment, a unique capability in the pharmaceutical industry.
  • Their focus on precision biologics and complex biologics sets them apart from competitors who may not specialize in these advanced therapeutic areas.
  • The recent $40 million Series A funding round underscores strong market interest and confidence in their innovative approach to drug development.