Principal Engineer
Automation
Confirmed live in the last 24 hours
Verve Therapeutics

201-500 employees

Develops gene editing therapies for heart disease
Company Overview
Verve Therapeutics, a clinical-stage biotechnology company, is a leading player in the fight against heart disease, leveraging its expertise in cardiovascular medicine, human genetics, and gene editing to develop transformative, once-and-done therapies. The company's unique approach to gene editing, designed to permanently lower LDL cholesterol and triglyceride levels, sets it apart from competitors and positions it at the forefront of precision genetic medicine. With a culture that fosters passion and drive, Verve has been recognized as a "Best Places to Work" by the Boston Globe, demonstrating its commitment to both its mission and its employees.
Biotechnology

Company Stage

N/A

Total Funding

$419.3M

Founded

2018

Headquarters

Boston, Massachusetts

Growth & Insights
Headcount

6 month growth

3%

1 year growth

15%

2 year growth

94%
Locations
Cambridge, MA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
Desired Skills
Python
SQL
Java
MATLAB
Data Analysis
CategoriesNew
Backend Engineering
IT & Support
Security Engineering
Software Engineering
Requirements
  • PhD in life sciences or engineering field with 6+ years of relevant industry experience
  • or M.S in life sciences or engineering field with 8+ years of relevant industry experience
  • or B.S. in life sciences or engineering field with 12+ years relevant industry experience
  • Experience implementing automation in genomics and NGS workflows is highly preferred
  • Strong technical background and familiarity with a wide range of automation technologies, including hardware and software systems, control systems, robotics, and data analytics
  • Previous experience with liquid handling platforms, laboratory automation equipment including Hamilton, Tecan, and Agilent based systems is required
  • Demonstrate advanced programming expertise with commercial liquid handlers and HTS software is required (Venus on Vantage, Fluent Control, and VWorks)
  • Experience implementing fully automated, end-to-end automation solutions, such as High Res Bio Systems or Biosero is desirable
  • Experience with and operational knowledge of immunoassay/ELISA based instruments such as flow cytometers, MesoScale, BioTek, Cytomat, and Multi-mode plate readers
  • Programming knowledge in .NET (VB, C#, ASP), Python, Java Script, SQL server, VBA Excel and Matlab are highly desired
  • Strong familiarity with the gene therapy development and discovery process
  • Experience leading a team of engineers and mentoring them as they progress in their careers
  • Excellent analytical and problem-solving skills, with the ability to identify and solve complex problems
  • Effective communicator with the ability to explain technical concepts to non-technical stakeholders and collaborate with cross-functional teams effectively
Responsibilities
  • Lead an in-house automation team to implement automation across the company to increase efficiency, standardization, and throughput of NGS workflows
  • Develop near-, mid-, and long-term strategies to automate various processes across different R&D groups, including NGS, Analytical Development, RNA Technology teams and more
  • Work closely with cross-functional teams, including, scientists, engineers, and IT professionals to identify opportunities for automation and ensure successful implementation of automation systems
  • Oversee the implementation of automation systems, including selecting appropriate hardware and software, configuring systems, testing and troubleshooting, and providing training to end-users
  • Manage automation projects from conception to completion, ensuring that projects are completed on time, within budget, and meet the desired objectives
  • Stay up to date with the latest developments in automation technology and industry best practices to ensure that Verve are at the forefront of automation innovation
  • Ensure that data generated using automation is accurate, reliable, and auditable and of the highest quality
  • Work with others in the automation team to script new methods, integrate hardware and optimize existing methods to enable high-throughput solutions used by internal teams.
  • Manage a fleet of liquid handling platforms, including creating SOPs, maintaining fleet health and scheduling preventative maintenance.
  • Work closely with Computational Biology, Quality Assurance, Quality Control, Information Technology, and Regulatory groups to ensure conformance of automation workflows with regulatory requirements as appropriate
  • Demonstrate exceptional time management skills and drive to support automation adoption and increase data output
  • Other duties as assigned