Job Description
Position description:
The Genetic Toxicology group within Nonclinical Drug Safety is seeking an experienced laboratory scientist with expertise in tissue culture, high content data acquisition (flow cytometery/image analysis) and molecular biology techniques associated with Next Generation Sequencing (NGS) such as DNA/RNA extraction and library preparation (fragmentation, adapter ligation) for high-throughput, error corrected sequencing.
The primary role of this position is to conduct experiments that enable cellular and chromosome/DNA damage screening in mammalian cell systems for the purpose of genetic toxicology risk assessment and risk management.
The individual in this position will be expected to work collaboratively across many disciplines and utilize resources and expertise available across our Company to grow expertise and apply new tools. This role includes designing and executing experiments, maintaining meticulous experimental records in an electronic notebook, summarizing data and communicating results. Additionally, this role includes engaging with the genetic toxicology field externally to stay informed on the latest testing strategies and approaches (e.g. attending Genetic Toxicology meetings and presenting research).
Position qualifications
Masters Degree in Molecular Biology or related field with at least 3 years post graduate experience or a Bachelor’s degree with at least 5 years relevant experience.
Required Experience and Skills
Expertise in tissue culture and molecular biology techniques associated with Next Generation Sequencing (NGS), experience with error corrected NGS preferred.
Preferred Experience and Skills
Experience with in vitro genetic toxicology endpoints such as micronucleus, mammalian mutation, biomarkers of genotoxicity etc, is a plus.
Experience with flow cytometry and/or high content image analysis a plus.
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
No relocation
VISA Sponsorship:
No
Travel Requirements:
10%
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
n/a
Job Posting End Date:
01/28/2025
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