Full-Time

Technical Chief of Staff

GTM & Operations

Mirendil

Mirendil

AI-driven discovery engine for biology

Compensation Overview

$250k - $400k/yr

+ Equity Grant

San Francisco, CA, USA

In Person

Category
Business & Strategy (1)

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Requirements
  • 6-10 years in high-growth tech: Chief of Staff, founder, early startup operator, GTM/BizOps leadership, management consultant, or top-tier strategy roles with an operating track record.
  • Fluent in the AI landscape: you understand models, the frontier lab ecosystem, and how AI products are built and sold. You can hold your own in technical conversations with researchers.
  • Proven at zero-to-one GTM: you've taken something new to market and closed early customers or partners, not just supported those who did.
  • Exceptional written and verbal communicator who can distill ambiguity into crisp decisions and narratives.
  • Extremely high energy and endurance. This is an intense, all-in role with long hours at a company moving at frontier-lab pace. You thrive on that, and you're at your best when the stakes and tempo are high.
  • Bias toward action. You default to doing, you're relentlessly resourceful, and nothing is beneath you or above you.
Responsibilities
  • Founder leverage. Drive the founders' highest-priority initiatives while providing the day-to-day operational support that keeps them focused on what matters most; preparing for critical partner and investor conversations, coordinating priorities, turning decisions into execution, and handling the details that keep the company moving.
  • Go-to-market from zero to one. Shape positioning, identify and land early design partners and customers, run pilots end-to-end, and build commercial motion.
  • Company operating rhythm. Build and run the systems that keep a research-driven company aligned and fast: planning cycles, goal tracking and internal KPIs, internal communications, and cross-team execution.
  • Special projects. Jump on whatever is most important and least owned - a partnership negotiation, a launch, a market analysis, an operational fire - and drive it to completion.

Mirendil develops AI models to accelerate breakthroughs in biology and materials science. Its AI discovery engine simulates molecular interactions and explores chemical space to speed up drug and material discovery, potentially integrating with robotic wet labs. Distinguishing factors include its neo-lab model, focusing on niche, science-driven applications rather than general-purpose AI, and a team of researchers from Anthropic and other AI labs with experience in scientific reasoning. The company’s goal is to shorten the time and reduce the cost of research and development by acting as a scientific co-pilot that guides experiments and simulations toward promising discoveries.

Company Size

N/A

Company Stage

Seed

Total Funding

$200M

Headquarters

San Francisco, California

Founded

2026

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Simplify Jobs

Simplify's Take

What believers are saying

  • Andreessen Horowitz led Mirendil’s $200 million seed at a $1 billion valuation.[8]
  • Nvidia participation can strengthen compute access and infrastructure support.[6][8]
  • The platform can automate data preparation, debugging, and experiment design.[2][3]

What critics are saying

  • No disclosed product or revenue creates immediate adoption and monetization risk.[9]
  • Autonomous self-upgrading systems raise control, safety, and trust concerns.[2][9]
  • Large labs can copy neo-lab talent and research-automation features quickly.[3][13]

What makes Mirendil unique

  • Former Anthropic, DeepMind, xAI, and OpenAI researchers built a 20-person team.[1][2]
  • Mirendil targets self-optimizing AI research, not general-purpose models.[2][3]
  • Its focus spans biology, materials science, and autonomous model development.[2][8]

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Company News

DN.com
Jun 25th, 2026
Mirendil, an AI company that secured $200 million in seed funding, has already locked in dual-brand domain names.

Mirendil, an AI company that secured $200 million in seed funding, has already locked in dual-brand domain names. 25 Jun 2026 05:44:01 PM By:DN editor Recently, AI startup Mirendil announced the completion of a $200 million seed round of financing, co-led by a16z and Kleiner Perkins, with NVIDIA also participating. Recently, AI startup Mirendil announced the completion of a $200 million seed round of financing, co-led by a16z and Kleiner Perkins, with NVIDIA also participating. The team members are all from leading AI labs such as OpenAI, DeepMind, xAI, and Anthropic, boasting a highly prestigious roster. This company was registered in Delaware, USA, in December 2025. Early in its business, the team acquired the brand domain names Mirendil.com and Mirendil.ai. A search revealed that Mirendil.ai had no publicly auctioned sales records, indicating it was acquired privately by the founders at a premium. Within just six months, this startup secured substantial funding, and its domain name strategy preceded its funding rounds. This is a common tactic in Silicon Valley AI startups: a high-quality brand name with a .com domain and a .ai domain is a standard digital asset for VCs investing heavily in AI projects. For domain investors, most high-quality AI brand name .ai domains are now traded privately, with fewer good options available on the open market. Therefore, strategically investing in early-stage brand domains remains a sound investment strategy.