Senior – Physician and Translational Lead for Neurological Diseases



201-500 employees

Machine learning-driven drug discovery and development

Data & Analytics
AI & Machine Learning

$260,000 - $350,000

Annual Performance Bonus Plan, Equity Incentive Plan


San Bruno, CA, USA

Required Skills
Data Science
  • MD or MD/PhD in a technical field (genetics, neuroscience, molecular biology, cellular biology, etc.) or equivalent, with 8+ years of experience.
  • Experience working with patients, patient data, patient trajectories/disease progression and clinical trial design.
  • Experience with biomarker data sets such as; proteomics, metabolomics, transcriptomic and/or imaging clinical data sets.
  • Experience working as part of a high-performance team, including goal setting, and contributing to a culture of high-quality methods development and reducing those methods to a practical implementation.
  • Strong verbal and written communication skills across all levels both within an organization and with external partners.
  • Lead efforts to design and execute ML-enabled clinical trials for internal and/or partnered programs.
  • Play an important strategic role in integration of the patient perspective to inform disease modeling and drug discovery efforts, including understanding the standard of care, areas of unmet need, and identifying viable target-patient profiles.
  • Partner with colleagues in data science and machine learning (DSML) and in corporate development to identify critical data assets and/or commission the generation of data for biomarker discovery in neuroscience.
  • Collaborate with DSML colleagues to define machine learning (ML) models for clinical data to inform our understanding of patient trajectory and patient subpopulations and to identify novel endpoints for clinical trials.
  • Longer-term, partner with market planning and commercial development colleagues on market research and target-patient profiles for new programs.
  • Contribute as a clinical area expert dedicated to delivering biomarker strategies for neuroscience.
  • Prepare IND-enabling data packages according to clinical development objectives.
  • Participate in strategic overview of presentations, publications, and internal/ external communications along with accountable project and program leadership.

Insitro stands out as a pioneering drug discovery and development company, utilizing machine learning and high-throughput biology to transform the traditional, often inefficient, process of creating medicines. The company's unique approach combines human genetics, functional genomics, and machine learning to construct predictive in vitro human cell-derived disease models, aiming to deliver more effective medicines faster and at a lower cost. With a diverse team of experts in life sciences, machine learning, human genetics, engineering, and drug discovery, insitro fosters a collaborative culture that integrates the languages of biology and machine learning, making it an ideal workplace for those seeking to advance tomorrow's medicines.

Company Stage

Series C

Total Funding



South San Francisco, California



Growth & Insights

6 month growth


1 year growth


2 year growth



Excellent medical, dental, and vision coverage

Excellent mental health and well-being support

Open vacation policy

Access to free onsite baristas & cafe with daily lunch and breakfast

Access to free onsite fitness center

Commuter benefits

Paid parental leave

Competitive pay and 401(k) matching

Flexible work schedule (on site and remote)