Full-Time

Vice President

Translational Biology

Confirmed live in the last 24 hours

Orbital Therapeutics

Orbital Therapeutics

51-200 employees

Develops RNA-based medicines and therapies

Biotechnology
Healthcare

Expert

Cambridge, MA, USA

Category
Bioinformatics
Biology Lab & Research
Biology & Biotech
Requirements
  • Ph.D. in immunology, genetics, bioengineering, or a related field.
  • Must have 12 years of postdoctoral experience as well as 7 years within biotechnology/pharmaceutical, including experience performing immunological research.
  • Broad scientific and technical expertise in immunology, particularly in autoimmune diseases and immune-oncology required.
  • Scientific and technical expertise in cell and gene therapy would be a plus.
  • Demonstrated strong ability to lead a team of experienced leaders required.
  • Experience with writing regulatory documents to support FIH studies required.
  • Takes accountability for actions and drives results.
  • Strong interpersonal and presentation skills with good judgment and ability to communicate with a diverse range of individuals.
Responsibilities
  • Work with the leadership team to provide strategy and vision and make decisions that establish objectives for the overall direction of Orbital’s research in line with company’s portfolio.
  • Innovate novel scientific projects/platforms for the company.
  • Develop essential methods for identifying clinical biomarkers and correlatives, including ensuring the appropriate collection, processing, and analysis of clinical samples.
  • Motivate and grow the research teams to achieve corporate objectives.
  • Oversee the development of preclinical IND packages for portfolio products, including nonclinical study reports and regulatory documents.
  • Work with the Clinical team to develop target candidate profiles and design experiments that support clinical plans.
  • Present experimental findings regularly to the leadership team and supervise the team members as they generate records, and present data.
  • Help draft progress reports and summaries for patent applications and/or scientific publications and provide external representation at conferences.

Orbital Therapeutics focuses on developing RNA-based medicines, specifically targeting areas like vaccines, immunomodulation, and protein replacement. The company utilizes RNA technology, advanced delivery methods, data science, and automation to create a platform for a wide range of therapeutic applications. Unlike many competitors, Orbital Therapeutics does not work with small interfering RNA, allowing it to carve out a unique niche in the genetic medicine space. The goal is to enhance global health by harnessing RNA medicines to treat diseases in innovative ways that were not possible before. Revenue is generated through the sale of these medicines to healthcare providers, who then administer them to patients.

Company Stage

Series A

Total Funding

$262.6M

Headquarters

San Francisco, California

Founded

2022

Growth & Insights
Headcount

6 month growth

9%

1 year growth

31%

2 year growth

235%
Simplify Jobs

Simplify's Take

What believers are saying

  • Increased interest in RNA therapies post-COVID-19 boosts Orbital's innovation opportunities.
  • Advancements in lipid nanoparticle technology enhance RNA therapy delivery mechanisms.
  • Growing personalized medicine trend aligns with Orbital's focus on tailored RNA solutions.

What critics are saying

  • Competition from established pharma companies may limit Orbital's market share.
  • Rapid RNA delivery advancements require continuous R&D investment, straining resources.
  • Potential regulatory hurdles could delay RNA-based therapy approvals and market entry.

What makes Orbital Therapeutics unique

  • Orbital Therapeutics focuses on RNA-based medicines excluding small interfering RNA.
  • The company integrates RNA technology with data analytics and automation for drug development.
  • Orbital's leadership includes experts like Dr. Giuseppe Ciaramella with extensive drug discovery experience.

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