Full-Time

Principal – Philanthropy-Remote

Posted on 8/29/2025

American Cancer Society

American Cancer Society

5,001-10,000 employees

Advocates, funds cancer research, supports patients

Compensation Overview

$150k - $175k/yr

Boston, MA, USA + 4 more

More locations: Houston, TX, USA | Rochester, MN, USA | Cleveland, OH, USA | Phoenix, AZ, USA

Remote

Category
Sales & Account Management (1)
Requirements
  • 5+ year proven track record of securing $1,000,000+ gifts or equivalent experience.
  • Bachelor's Degree
  • Experience in multi-million nonprofit is necessary
  • Excellent oral and written communication skills are required, as is computer proficiency.
  • Role responsible for a major gifts portfolio of philanthropists capable of making gifts of $1 million or greater.
  • Accountability for more than $100M in revenue inclusive of capital campaigns.
  • Demonstrates Major Gifts/Planned Giving Competencies: Customer focus - Builds strong customer relationships and delivering customer-centric solutions.
  • Strategic mindset - Sees ahead to future possibilities and translates them into breakthrough strategies.
  • Action oriented - Takes on new opportunities and tough challenges with a sense of urgency, high energy, and enthusiasm
  • Drives results - Consistently achieves results, even under tough circumstances.
  • Interpersonal savvy - Relates openly and comfortably with diverse groups of people.
  • Builds networks - Effectively builds formal and informal relationship networks inside and outside the organization.
  • Persuades - Uses compelling arguments to gain the support and commitment of others.
  • Being resilient - Rebounds from setbacks and adversity when facing difficult situations.
Responsibilities
  • Work in collaboration with Senior Leadership, EVPs and Regional Philanthropy staff to maximize giving opportunities and external working relationships with high value constituents to strengthen projects and proposals to meet funder's requirements and succeed competitively.
  • Manage relationship and solicitations of the Society's highest level
  • Develop and execute on nationwide fundraising strategy for mission priorities
  • Must be a strong ambassador for the organization and at all times deliver the mission of the organization to the constituent with an opportunity to take action
  • Work collaboratively with a team approach in all aspects of the position.
  • Manage a qualified constituent portfolio of 25 -- 50 Nationwide/Global High Net Worth constituents that have giving capacity of $1 million or greater on behalf of the organization and reflect an organization strategy.
  • Consolidate knowledge of funding opportunities within individuals, and foundations to maximize the Society's relationship efforts, including current funding pillars such as Patient Support, Discovery, and Advocacy, and other innovative projects.
  • Manage and report activity centered around Board members, Senior Leadership, and regions on a regular basis to management.
  • Work with dedicated Mission staff to develop and fund opportunities for potential donors.
  • Manage the complete cultivation, solicitation, and stewardship strategy as appropriate.
  • Serve as a guide and resource to secure funding for the organization in the most efficient and collaborative way.
  • Work with assigned department leaders to develop, expand and refine case for support, supporting materials and strategy for use not only with national proposals but also used by Philanthropy Officers in the field.
  • Secure a minimum of $3,000,000-$5,000,000+ annually in major gifts through moves management based on tenure, with accountability for overall $100M Philanthropy budget through: 1. A minimum of (5) 7-figure solicitations annually; 2. 25 donors in cultivation; 3. 25 donors in identification; 4. All donors in stewardship
  • Supporting the effective development of campaign packaging, pricing, and lead gifts for field staff proposals.
  • Coordinate the stewardship of $1million + donors
  • Understand and execute on a $4B enterprise-wide All In Against Cancer campaign.
Desired Qualifications
  • Ideal candidate will have experience in major gifts within a major metropolitan area
  • Experience in health, healthcare, oncology and/or scientific related fundraising is preferred.
  • Experience in multi-million nonprofit is necessary
American Cancer Society

American Cancer Society

View

American Cancer Society works to end cancer by combining advocacy, research, and patient support. It funds and conducts cancer research, provides information and education to prevent and detect cancer, and offers services to help patients and families during treatment. Its nationwide programs include a patient helpline, support resources, and policy advocacy to improve access to care. What sets it apart is its comprehensive, end-to-end approach that connects scientific research with practical support and public policy, aiming to improve quality of life for people affected by cancer. The organization’s goal is to end cancer as we know it for everyone by enabling prevention, early detection, effective treatment, and survival.

Company Size

5,001-10,000

Company Stage

Series B

Total Funding

$2.7M

Headquarters

Atlanta, Georgia

Founded

2000

Simplify Jobs

Simplify's Take

What believers are saying

  • The colorectal blood-test update creates outreach to unscreened adults.
  • ACS can promote navigation-heavy screening models with health-system partners.
  • Fundraising events still mobilize sizable local donor bases in major cities.

What critics are saying

  • Shield’s weak polyp detection can erode ACS prevention credibility.
  • The blood test’s premium pricing limits uptake and payer enthusiasm.
  • New journals risk thin submissions and low influence against entrenched oncology brands.

What makes American Cancer Society unique

  • ACS pairs screening guidelines with research, journals, and patient-support programs.
  • Its new pediatric and AYA journal broadens ACS beyond adult oncology.
  • ACS funds community-based digital inclusion projects tied to cancer outcomes.

Help us improve and share your feedback! Did you find this helpful?

Your Connections

People at American Cancer Society who can refer or advise you

Benefits

Health Insurance

Dental Insurance

Paid Vacation

401(k) Retirement Plan

Wellness Program

Professional Development Budget

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

0%

2 year growth

0%
Newswise
Apr 8th, 2026
American Cancer Society announces new Pediatric, Adolescent, and Young Adult Cancer Journal; names editor-in-chief.

American Cancer Society announces new Pediatric, Adolescent, and Young Adult Cancer Journal; names editor-in-chief. Credit: American Cancer Society New ACS Pediatric Cancer Journal Newswise - The American Cancer Society (ACS) today announced the launch of its fourth medical journal, Pediatric, Adolescent & Young Adult Cancer. This international, multidisciplinary publication will feature peer-reviewed original research and solicited content on the latest advances in cancers affecting children, adolescents, and young adults (AYA). The open-access journal will serve as a vital resource for those dedicated to advancing prevention, early detection, treatment, and survivorship in all areas of pediatric and AYA oncology. Physician-scientist Dr. Nirali N. Shah has been named the inaugural editor-in-chief. "This new journal provides a unique forum dedicated to comprehensively highlighting cutting-edge efforts in pediatric, adolescent, and young adult cancer, serving as a beacon for medical and scientific research professionals," said Dr. William Dahut, chief scientific officer at the American Cancer Society. "Also, the addition of Dr. Shah as editor-in-chief will provide the expert leadership needed for rigorous, collaborative research that advances care and outcomes across the pediatric, adolescent, and young adult cancer continuum." Dr. Shah serves as the head of the hematologic malignancies section in the pediatric oncology branch at the National Cancer Institute. She leads a research program focused on developing targeted immunotherapies for high-risk blood cancers in children, adolescents, and young adults. Her clinical and translational work centers on chimeric antigen receptor (CAR) T-cell and antibody-based therapies aimed at improving outcomes while reducing treatment-related toxicities and late effects. "With rising rates of cancer in adolescents and young adults, the journal will provide an opportunity to address and broadly communicate some of the greatest challenges faced in cancer care by this vulnerable population," said Dr. Shah. "With the foundation of the ACS, and through highlighting the latest and greatest in pediatric and AYA oncology, the journal is poised to bring forward meaningful change to enhance quality of care and improve outcomes for pediatric, adolescent, and young adult patients." The journal will focus on the following key areas in pediatric and AYA cancer: * Providing a platform for researchers, clinicians, and advocates to share discoveries and advance knowledge across the field of oncology * Novel treatment approaches, prevention strategies, and epidemiologic studies * Artificial intelligence-driven insights and bioinformatics breakthroughs * Advancing cancer care and improving outcomes worldwide Additionally, the types of articles to be published include: * Original articles * Review articles * Commentaries * Brief reports * Clinical practice guidelines * Consensus statements * Policy and practice * Beyond the diagnosis (essays from clinicians, patients, and caregivers) * Letters to the editor * Virtual tumor board * Editorials The Pediatric, Adolescent & Young Adult Cancer journal will be produced quarterly, with the first issue planned for late summer. ACS is currently accepting submissions from medical and scientific experts here.

PR Newswire
Apr 7th, 2026
American Cancer Society launches fourth medical journal focused on pediatric and young adult cancer

The American Cancer Society has launched its fourth medical journal, Pediatric, Adolescent & Young Adult Cancer, an open-access publication dedicated to research on cancers affecting children and young adults. Dr Nirali N. Shah, head of the haematologic malignancies section at the National Cancer Institute, has been named inaugural editor-in-chief. The international, multidisciplinary journal will publish peer-reviewed original research and solicited content on prevention, early detection, treatment and survivorship. It will cover novel treatment approaches, epidemiologic studies, AI-driven insights and bioinformatics breakthroughs. The quarterly journal will launch in late summer 2026 and is currently accepting submissions. The American Cancer Society's three other journals are CA: A Cancer Journal for Clinicians, Cancer, and Cancer Cytopathology.

The Associated Press
Apr 6th, 2026
Workout Anytime and baseball star KJ Jackson host charity event for American Cancer Society

Workout Anytime and Savannah baseball star Kyle "KJ" Jackson are hosting a community event on 13 April at the fitness brand's Thomasville, North Carolina location to raise funds for the American Cancer Society. The meet-and-greet will feature Jackson, who was recently appointed as Workout Anytime's first-ever Chief Aura Officer, encouraging attendees to participate in a "Battle Rope Challenge" with donations going to the charity. The event, running from 3pm to 6pm, is open to members and non-members alike. Activities include meeting Jackson for photos and autographs, alongside food trucks, bounce houses and a live DJ. Jackson's role as Chief Aura Officer focuses on driving culture and community across Workout Anytime's 190-plus clubs nationwide.

PR Newswire
Apr 6th, 2026
Workout Anytime appoints first Chief Aura Officer to boost community engagement

Workout Anytime is hosting a community fundraising event for the American Cancer Society on 13 April at its Thomasville, North Carolina location. The meet-and-greet will feature Kyle "KJ" Jackson, a Savannah baseball star recently appointed as the fitness brand's first Chief Aura Officer. Attendees can participate in the "Battle Rope Challenge" and make donations to the American Cancer Society. The event, running from 3pm to 6pm, will include opportunities to meet Jackson, take photos and receive autographs, alongside food trucks, bounce houses and a live DJ. As Chief Aura Officer, Jackson's role focuses on driving culture, connection and community across Workout Anytime's 190-plus locations nationwide. The Atlanta-based 24/7 fitness brand operates premium facilities at accessible prices.

Chicago Business
Mar 27th, 2026
American Cancer Society gala spotlights hope and raises $1.86 million.

American Cancer Society gala spotlights hope and raises $1.86 million. March 27, 2026 09:00 AM CDT The American Cancer Society hosted its 19th annual Chicago Discovery Ball on Feb. 28 at the Sheraton Grand Chicago Riverwalk, drawing 526 supporters and raising $1.86 million for cancer research and patient programs. Roughly four years after the end of the COVID-19 pandemic, the night life scene in Chicago is enjoying a quiet renaissance, operators tell Crain's. Staying current is easy with newsletters delivered straight to your inbox.

INACTIVE