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Full-Time

Scientist – Hybrid Computational / Synthetic Biology

Confirmed live in the last 24 hours

Manifold Bio

Manifold Bio

11-50 employees

Designs precision biologics using in vivo methods

Biotechnology
Healthcare

Senior, Expert

Boston, MA, USA

Hybrid position requiring in-office presence.

Category
Bioinformatics
Computational Biology
Biology Lab & Research
Biology & Biotech
Required Skills
Python
Git
AWS
Data Analysis
Requirements
  • PhD or equivalent experience in protein and or molecular biology, biological engineering or a related field; must total 5+ years hands-on molecular biology wet lab experience and/or NGS data analysis experience
  • Experience going end-to-end from experimental design through cloning, execution, NGS, and analysis
  • Expertise in statistical computing and willingness to adapt our python / jupyter / git / AWS stack
  • Collaborative, curious, flexible, and strong communication skills
Responsibilities
  • Design, execute, interpret and iterate on novel library-based experiments
  • Apply statistical methods and machine learning to NGS data to identify novel variants
  • Provide deepful insightful analyses of team’s NGS experiments and advise on next steps
  • Develop novel protein engineering platform technologies

Manifold Bio specializes in creating precision biologics for the pharmaceutical industry, focusing on drug design and development. Their main product is an in vivo drug design platform, which allows for testing drugs within living organisms rather than in laboratory settings. This platform utilizes mCodes™ technology, a unique protein barcoding system that enables the simultaneous study of multiple proteins in one experiment, making it particularly effective for complex biologics. Unlike other companies, Manifold Bio's approach to in vivo testing is the first of its kind, setting them apart in the market. The company's goal is to expand their platform and collaborate with other pharmaceutical companies to develop new therapeutics, leveraging their innovative technology to meet the growing demand for advanced drug solutions.

Company Stage

Series A

Total Funding

$45.4M

Headquarters

Boston, Massachusetts

Founded

2020

Growth & Insights
Headcount

6 month growth

0%

1 year growth

2%

2 year growth

68%
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Simplify's Take

What believers are saying

  • The significant Series A funding provides ample resources for expanding their in vivo biologics design platform, potentially accelerating growth and innovation.
  • Manifold Bio's technology could revolutionize the drug discovery process by overcoming the bottleneck of in vivo testing, making it more efficient and cost-effective.
  • Partnerships and collaborations with other pharmaceutical companies could lead to lucrative licensing deals and revenue streams.

What critics are saying

  • The highly specialized nature of their technology may limit their market to a niche segment within the pharmaceutical industry.
  • Dependence on successful integration and performance of their mCodes™ technology in real-world applications could pose a risk if the technology does not meet expectations.

What makes Manifold Bio unique

  • Manifold Bio's in vivo drug design platform, powered by their proprietary mCodes™ technology, allows for simultaneous testing of multiple proteins in a single experiment, a unique capability in the pharmaceutical industry.
  • Their focus on precision biologics and complex biologics sets them apart from competitors who may not specialize in these advanced therapeutic areas.
  • The recent $40 million Series A funding round underscores strong market interest and confidence in their innovative approach to drug development.