Full-Time

Data Architect

Clinical

Prolaio

Prolaio

51-200 employees

Real-time cardiovascular care analytics platform

Compensation Overview

$148k/yr

+ Bonus + Equity

Chicago, IL, USA

In Person

Category
Data & Analytics (1)
Required Skills
Talend
Microsoft Azure
Redshift
Python
Airflow
BigQuery
Apache Spark
SQL
Apache Kafka
AWS
REST APIs
Informatica
Databricks
Snowflake
Google Cloud Platform

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Requirements
  • Bachelor’s degree in computer science, Data Engineering, Information Systems, Biomedical Informatics, Engineering, or a related field.
  • Minimum 10 years of experience in healthcare, life sciences, medtech, digital health, or other patient-data-focused environments, including at least 5 years in clinical data, real-world data, clinical trials data, or other patient-centered data platforms.
  • Demonstrated experience architecting healthcare data platforms that support structured, semi-structured, and unstructured data in regulated or validated environments.
  • Deep understanding of data from cardiology focused wearables devices, claims, socioeconomic, behavioral, and EHR.
  • Deep understanding of healthcare data domains, data modeling, standardization, normalization, and the application of healthcare terminologies and common data models.
  • Strong experience working in a cross-functional, matrixed organization and partnering effectively with Product, Engineering, Data Science, Analytics, Clinical Operations, Quality, and Security teams, with the ability to operate as a self-starter in a growth-stage environment.
  • Strong familiarity with cloud platforms such as GCP, AWS, or Azure and modern data platforms such as Snowflake, Databricks, BigQuery, Redshift, Synapse, or comparable environments.
  • Experience with ETL or ELT, orchestration, and large-scale data processing tools such as dbt, Airflow, Dagster, Spark, Kafka, Fivetran, Informatica, Talend, or similar technologies.
  • Strong SQL and Python skills, with familiarity in APIs, event-driven architectures, interoperability frameworks, and clinical data exchange patterns such as HL7 and FHIR
  • Familiarity with metadata, lineage, catalog, governance, and AI-enablement tools, including platforms for semantic indexing, vectorization, retrieval, and data lifecycle automation.
Responsibilities
  • Define the target-state data architecture and roadmap for Prolaio’s regulated healthcare data platform in support of product, analytics, data science, data services, clinical operations, and quality use cases.
  • Architect scalable, secure, and interoperable data platforms that support structured, semi-structured, and unstructured data across clinical, operational, device, and patient-generated sources relevant to Prolaio’s cardiovascular and research mission.
  • Lead architecture decisions for storage, compute, orchestration, metadata, APIs, and integration patterns across cloud-native environments and modern data platforms.
  • Establish architecture standards and reference patterns that support reliability, performance, extensibility, and validated operation in regulated settings.
  • Design and govern conceptual, logical, and physical data models for clinical trials, cardiovascular and physiological data, real-world data, claims, medication, socio-economic, behavioral, and related healthcare datasets.
  • Apply healthcare terminologies, ontologies, and common data models where appropriate, including standards such as HL7, FHIR, ICD, SNOMED CT, LOINC, RxNorm, OMOP, and CDISC.
  • Lead efforts to standardize and normalize disparate data sources into governed, reusable, analysis-ready datasets suitable for regulated workflows, clinical research, and product development.
  • Architect end-to-end data flows and reusable pipelines for ingestion, validation, transformation, enrichment, publishing, retention, archival, and decommissioning across batch, streaming, and hybrid workloads.
  • Define and implement data lifecycle management practices that support retention, access control, traceability, reproducibility, lineage, provenance, and auditability in regulated healthcare environments.
  • Design data architectures that enable AI, analytics, and machine learning use cases by supporting feature generation, retrieval workflows, governed access, and production deployment needs.

Prolaio provides a cardiovascular-focused health tech platform that helps healthcare providers improve patient outcomes through real-time data analytics and continuous monitoring. It collects data from electronic health records, patient surveys, and wearable sensors to build predictive models that warn care teams about potential health issues before they become critical. Healthcare providers access the platform via a subscription, giving them real-time analytics, alerts, and evidence-based care planning tools to monitor patients and optimize treatments. The company differentiates itself by concentrating on cardiovascular care and enabling continuous learning, patient engagement, and collaboration with pharmaceutical companies and research institutions to support new therapies. The overall goal is to reduce hospital admissions and readmissions while delivering timely, data-driven care that keeps patients healthier.

Company Size

51-200

Company Stage

Early VC

Total Funding

$25.5M

Headquarters

Scottsdale, Arizona

Founded

2022

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Simplify Jobs

Simplify's Take

What believers are saying

  • Kardigan acquisition integrates Prolaio's data platform with cardiac intelligence.
  • Supports all-remote heart studies generating high-density CV insights.
  • Curates largest CV dataset to prevent avoidable heart events.

What critics are saying

  • Data incompatibility with Kardigan's R&D systems erodes value in 12-18 months.
  • FDA scrutiny halts platform use in trials and triggers fines in 6-12 months.
  • Key personnel loss stalls analytics updates in 3-6 months.

What makes Prolaio unique

  • Prolaio's FDA-cleared software integrates real-world CV data with proprietary algorithms.
  • Comprehensive patient kit includes wrist monitor, smart cuff, scale, and ECG patches.
  • Tech-enabled trial enrichment optimizes CV study design and boosts statistical power.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

Unlimited Paid Time Off

Flexible Work Hours

Remote Work Options

Paid Vacation

Paid Sick Leave

Paid Holidays

Hybrid Work Options

401(k) Retirement Plan

401(k) Company Match

Performance Bonus

Stock Options

Company Equity

Retirement Plan: 401(k) plan

Paid Time Off

Growth & Insights and Company News

Headcount

6 month growth

-8%

1 year growth

-3%

2 year growth

-7%
Business Wire
Mar 28th, 2025
Kardigan Acquires Prolaio to Create a Pioneering Heart Health Company with One-of-a-Kind Integrated Cardiovascular Data and Therapeutics Platform

Kardigan, a heart health company modernizing cardiovascular (CV) drug development, announced today that it has acquired Prolaio, a clinical intelligence comp...

Securities and Exchange Commission
Sep 13th, 2023
SEC FORM D

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.The reader should not assume that the information is accurate and complete.