Scientist I @ ArsenalBio

WHO WE ARE:

ArsenalBio, a privately held, clinical-stage programmable cell therapy company engineering advanced CAR T therapies for solid tumors, is seeking a talented scientist to work onsite based in our SOUTH SAN FRANCISCO office.

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. With our programmable and computationally driven approach, our team is engineering living medicines to attack cancer’s inherent multi-faceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across immunology, synthetic biology, molecular biology, automation and computational biology, we are united in purpose to deliver radical breakthroughs for people with cancer, and prioritize the team’s outcomes over individual goals to achieve our company mission – together.

This means you’ll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most.

We are seeking an outstanding scientist to drive next-generation sequencing methods within ArsenalBio. The ideal candidate will have a broad understanding of NGS and its applications and a proven track record of executing innovative NGS protocols for solving complex biological problems. As a strong technical contributor, this role will collaborate with internal and external stakeholders to advance ArsenalBio research.

WHAT YOU WILL DO:

Deploy high- and low-throughput NGS library preparation strategies for bulk, single-cell, and multi-omic applications
Create NGS libraries from single cells, tissues, and isolated DNA/RNA to further ArsenalBio research and discovery
Assist in troubleshooting problematic library preps and sequencing issues
Establish novel NGS methods to extract new types of information from research and clinical samples
Help oversee the operation and maintenance of numerous Illumina instruments
Contribute to ongoing improvements in storing, tracking, and analyzing NGS data
Participate in cross-functional collaborations with multiple groups to advance broad company goals and objectives and assist in the design of genomics projects
Contribute NGS expertise, leadership, and technical guidance to cross-disciplinary teams.
Advance NGS technology utilization and understanding across the company
Work closely with computational biologists to interpret NGS data

WHO YOU ARE:

Ph.D. in Genetics, Biology, Biochemistry, Chemistry, or a related discipline with 0-2 years relevant experience; or Masters with 5+ years of relevant experience; or Bachelors with 7+ years of relevant experience
3+ years of full-time, hands-on NGS experience in an academic or industrial setting
Deep understanding of NGS library preparation and the principles of sequencing technologies
Previous work with a variety of NGS sample preparation workflows and analysis
Experience in high-content screening, single-cell genomics, or functional genomics
Significant experience in troubleshooting, method development, and optimization of molecular biology-based assaysExceptional organizational skills and attention to detail
Sound understanding of molecular biology and analytical techniques, including PCR/qPCR, ddPCR, molecular cloning, gene editing, enzymatic assays, and nucleic acid isolation and manipulation
Experience operating liquid handling robots or other lab automation for high-throughput assays preferrableFamiliarity in computational analysis of next-generation sequencing data
Ability to quickly learn new skills and knowledge on the job, demonstrate productivity and deliver high-quality results

BENEFITS AND PAY:

An opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM to advance therapies to patients who need it most.

ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge.

We have a robust mentorship program, and comprehensive development tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as they are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.

We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

We are an equal-opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

The estimated base salary offer for the primary location of the San Francisco Bay area ranges from $110,200 - 135,000. Salary ranges for other locations may vary from this range. Base pay offered may vary depending on job-related knowledge, experience, education, and location.

In addition to these factors, we believe in the importance of pay equity and consider internal equity of our current employees as part of any final offer.

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

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Scientist I

NGS & Molecular Assays, 24120-R-690-NGS

ArsenalBio

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