Full-Time

Scientist I

NGS & Molecular Assays, 24120-R-690-NGS

Posted on 7/30/2024

ArsenalBio

ArsenalBio

201-500 employees

Develops programmable cell therapies for cancer

Biotechnology
Healthcare

Compensation Overview

$110.2k - $135kAnnually

Entry, Junior, Mid

San Bruno, CA, USA

Position requires onsite presence in South San Francisco.

Category
Computational Biology
Genomics
Biology & Biotech
Requirements
  • Ph.D. in Genetics, Biology, Biochemistry, Chemistry, or a related discipline with 0-2 years relevant experience; or Masters with 5+ years of relevant experience; or Bachelors with 7+ years of relevant experience
  • 3+ years of full-time, hands-on NGS experience in an academic or industrial setting
  • Deep understanding of NGS library preparation and the principles of sequencing technologies
  • Previous work with a variety of NGS sample preparation workflows and analysis
  • Experience in high-content screening, single-cell genomics, or functional genomics
  • Significant experience in troubleshooting, method development, and optimization of molecular biology-based assays
  • Exceptional organizational skills and attention to detail
  • Sound understanding of molecular biology and analytical techniques, including PCR/qPCR, ddPCR, molecular cloning, gene editing, enzymatic assays, and nucleic acid isolation and manipulation
  • Experience operating liquid handling robots or other lab automation for high-throughput assays preferable
  • Familiarity in computational analysis of next-generation sequencing data
  • Ability to quickly learn new skills and knowledge on the job, demonstrate productivity and deliver high-quality results
Responsibilities
  • Deploy high- and low-throughput NGS library preparation strategies for bulk, single-cell, and multi-omic applications
  • Create NGS libraries from single cells, tissues, and isolated DNA/RNA to further ArsenalBio research and discovery
  • Assist in troubleshooting problematic library preps and sequencing issues
  • Establish novel NGS methods to extract new types of information from research and clinical samples
  • Help oversee the operation and maintenance of numerous Illumina instruments
  • Contribute to ongoing improvements in storing, tracking, and analyzing NGS data
  • Participate in cross-functional collaborations with multiple groups to advance broad company goals and objectives and assist in the design of genomics projects
  • Contribute NGS expertise, leadership, and technical guidance to cross-disciplinary teams.
  • Advance NGS technology utilization and understanding across the company
  • Work closely with computational biologists to interpret NGS data

ArsenalBio focuses on developing programmable cell therapies to treat solid tumor cancers. Their approach involves reprogramming cells to enhance their ability to fight cancer. The company is currently in the clinical stage, concentrating on research and development to bring these therapies to market. Their target audience includes patients with solid tumor cancers, a significant segment of cancer patients worldwide. ArsenalBio aims to generate revenue through the commercialization of their therapies once they receive approval. The team consists of experts from various scientific fields and professionals with clinical and manufacturing backgrounds, all working together to create effective cancer treatments.

Company Stage

Series C

Total Funding

$612.8M

Headquarters

San Francisco, California

Founded

2019

Growth & Insights
Headcount

6 month growth

-2%

1 year growth

-1%

2 year growth

15%
Simplify Jobs

Simplify's Take

What believers are saying

  • ArsenalBio secured $325 million in Series C funding for therapy development.
  • The first patient was dosed in a Phase 1/2 trial for renal cell carcinoma.
  • Collaboration with Genentech enhances T-cell therapy research and development.

What critics are saying

  • Competition from CRISPR Therapeutics and Editas Medicine in cancer treatment.
  • High development costs may limit ArsenalBio's ability to scale therapies.
  • Regulatory hurdles could delay market entry and affect revenue generation.

What makes ArsenalBio unique

  • ArsenalBio uses CRISPR-based genome engineering for precise cell therapy development.
  • The company integrates machine learning to enhance immune cell therapy efficacy.
  • ArsenalBio's CITE technology targets tumor microenvironments, improving therapy effectiveness.

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Benefits

Medical, dental, & vision coverage

Virtual & telehealth options

Parental leave

Flexible work schedule

Flexible PTO

Mental health resources

INACTIVE