Fall 2023 Co-op: Mrna Process Development
Posted on 2/28/2023
Prime Medicine

51-200 employees

Gene editing biotechnology company
Company Overview
Prime Medicine's mission is to transform the lives of patients with debilitating diseases through the application of our groundbreaking Prime Editing platform and technology. The company uses Prime Editing, a next-generation gene editing approach that they believe can address the genetic cause of disease and potentially provide patients with long-lasting cures.
Cambridge, MA, USA
Experience Level
Desired Skills
Medical, Clinical & Veterinary
Biology & Biotech
  • Enrolled in B.S./M.S. in Chemical Engineering, chemistry, Bioengineering or Biochemistry
  • Curious, ability to work independently or collaboratively as needed
  • Self-motivated, detail-oriented with strong critical thinking skills and excel at identifying and solving problems
  • Excellent written and verbal communication skills
  • Collaborate with the mRNA PD team and cross-functional teams to design and execute experiments supporting Prime Medicine goals
  • Execute experiments to optimize and understand robustness of mRNA IVT, with a focus on downstream processes
  • Perform analytical testing for assessing mRNA quality
  • Effectively communicate results to internal and external meetings, and present final summary to the team
  • Document and manage all experimental planning and progress in electronic lab notebook in an organized manner, providing statistical analysis and troubleshooting where appropriate
Desired Qualifications
  • Prior experience with mRNA in vitro transcription, chromatography, and wet lab is preferred
  • Knowledge of tangential flow filtration, HPLC/UPLC instrumentation, Fragment Analyzer a plus