Protein Purification Scientist

Job Description

• Vaccine Immunotherapeutic (VITx) seeks to discover novel vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human disease using a variety of vaccine technology platforms combined with immunomodulatory agents.

• A scientist is required to join Vaccine Immunotherapeutic in La Jolla, California, to develop and support vaccine platform production processes at the research scale

• The candidate will have solid training and knowledge in mammalian cell culture and virus/protein purification

• The candidate will be able to independently and proactively apply this knowledge in the design and execution of experimental work, to enable progression of vaccine discovery projects.

• The candidate will be required to work semi-independently and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones

• The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work.

• Laboratory and related work (80-90% of time) under daily to weekly supervision.

• Work with supervisor to define aim and a plan to achieve that aim, will then execute work following the plan (independently, if familiar with area of work, with guidance if unfamiliar)

• Experimental design in consultation with supervisor, literature review, and increasing emphasis on independent design based on experience

• Will carry out on-going analysis of data generated and will identify problems

• Will implement necessary changes following discussion with peers/ supervisor.

• Will analyze and interpret experimental data, results and methodology used with guidance.

• Will gain skills and experience to be fully conversant with the operation and validation of all items of equipment or IT needed for experimentation, data analysis, storage and data entry.

• Be able to review literature and suggest/apply to technical solutions to bioprocess problems of moderate complexity

• Daily entry into electronic laboratory notebooks

• Preparation of presentation materials. 

• Regular 1:1 communication with supervisor and team colleagues & Other colleagues within Vaccine Immunotherapeutic

• Developing communication/presentation skills at internal meetings/poster sessions & Safe working and regulatory compliance.

• Work safely themselves and be aware of EHS practices of other colleagues

• Completion of risk assessments, compliance training as required

• Acts independently to maintain a safe and EHS compliant desk and workspace

Qualifications

• Experience in most or all of the following areas are essential- protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems & tangential flow ultrafiltration and routine protein characterization techniques (SDS-PAGE, Western Blotting, BCA etc.)

• In addition, experience in adherent and suspension mammalian cell culture along with transient protein expression is desirable.

• The candidate will be required to work semi-independently and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones. The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work.

• BSc or MSc in biological sciences or biochemical/chemical engineering

• At least 1 year working in a laboratory in an academic or industrial settings

Additional Information

Warm Regards

Ricky Bansal

732-429-1925