Full-Time
Computer Systems Engineer 3
Posted on 7/25/2026
Lawrence Berkeley National Laboratory
5,001-10,000 employees
Fundamental science enabling energy and environment
Compensation Overview
$156.9k - $191.7k/yr
Berkeley, CA, USA
In Person
On-site at Lawrence Berkeley National Laboratory; remote work not offered.
 AI & Machine Learning (1) |
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- Bachelor's degree in Applied Mathematics, Statistics, Machine Learning, Computational Science, or a related field with a minimum of 8 years of related experience; or a Master's degree with 6 years of related experience; or equivalent experience.
- Strong, demonstrated background in machine learning, artificial intelligence, numerical optimization, and programming.
- Demonstrated experience in the design, development, deployment, and application of machine learning, agentic AI, and multi-fidelity optimization algorithms.
- Proven experience developing software tools and algorithms for autonomous experimentation, inverse design, software optimization, or related domains, along with experience working on high-performance computing (HPC) platforms.
- Analytical skills critical for designing, deploying, and applying AI/ML/optimization algorithms, paired with excellent Python programming skills.
- Experience with software project management and demonstrated experience leading cross-functional teams.
- Excellent oral, written, and interpersonal communication skills, with the ability and desire to work effectively within an energetic cross-disciplinary team.
- Proven ability to work effectively while balancing multiple competing priorities and tasks.
- Develop, apply, and deploy advanced software tools for numerical optimization, active learning, machine learning, and artificial intelligence tailored to science and engineering domains.
- Design, develop, test, benchmark, deploy, and tune agentic AI software frameworks and multi-fidelity optimization algorithms to close the feedback loop for automated scientific discovery.
- Deploy, optimize, and tune algorithms and software developments within high-performance computing (HPC) environments.
- Collaborate actively in a multidisciplinary team environment comprising scientists from energy technologies, physical sciences, mathematics, and computing.
- Resolve complex research and engineering issues by analyzing variable factors and exercising judgment to select optimal methods, techniques, and evaluation criteria.
- Publish developed algorithms as open-source software packages, maintain code documentation, and contribute to peer-reviewed journal articles and research proposals.
- Coordinate and lead software engineering and science teams in defining system requirements, software features, user interfaces, and overall software development processes.
- Mentor junior staff and developers while proactively establishing strategic partnerships with internal and external research teams to advance collaborative project goals.
- Master's degree with a minimum of 6 years of experience, or a Ph.D. with 4 years of experience, or equivalent experience preferred.
Berkeley Lab is a national research facility that conducts unclassified basic science across many fields, funded by the U.S. Department of Energy and managed by the University of California. Its work aims to address energy and environmental challenges by using interdisciplinary teams and building advanced tools for scientific discovery. Researchers study biosciences, computing sciences, Earth and environmental sciences, energy sciences and technologies, and physical sciences. The lab hosts about 4,200 scientists, engineers, staff, and students on a 200-acre site near UC Berkeley, and it has earned many prestigious honors, including Nobel Prizes and national academy memberships. Its goal is to generate foundational science that leads to practical, transformational solutions for energy and environmental issues while training the next generation of scientists and engineers.
Company Size
5,001-10,000
Company Stage
Grant
Total Funding
$2M
Headquarters
Berkeley, California
Founded
1931
Get referred to Lawrence Berkeley National Laboratory
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Simplify's Take
What believers are saying
- Cross-domain research enables commercialization of energy, climate, and computing breakthroughs.[4][5][7]
- High talent density strengthens partnerships with industry and federal agencies.[3][4]
- User facilities and advanced tools accelerate translation from fundamental science to applied solutions.[3][7]
What critics are saying
- Federal funding volatility can delay programs and pressure staffing across the lab.[4][5]
- Campus and infrastructure disruptions can halt experiments and user-facility operations.[3][4]
- Talent departures would damage recruiting, partnerships, and the lab's prestige-driven influence.[3][4]
What makes Lawrence Berkeley National Laboratory unique
- DOE Office of Science lab spanning energy, environment, computing, biosciences, and physics.[4][5]
- Berkeley Lab scientists have won 11 to 16 Nobel Prizes, depending on source.[1][2][3][4][6]
- UC-managed national laboratory with five user research facilities and deep scientific prestige.[3][4][5]
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↑ 3%New federal dataset and $67M in BTO funding reshape how operators plan for building energy demand. The DOE's Building Technologies Office (BTO) is reshaping building energy demand planning by deploying over $67 million in R&D funding for 2024. Additionally, Lawrence Berkeley National Laboratory and the National Renewable Energy Laboratory have released a comprehensive county-level energy demand dataset extending through 2050. This initiative aims to enhance the strategies of operators in anticipating and handling future energy needs. This story was produced through MarketScale. See how Energy teams put it to work with Customer Stories & Case Studies. By MarketScale Newsroom · July 20, 2026, 1:44 PM PDT · Department of Energy Building Technologies Office Lawrence Berkeley National Laboratory National Laboratory of the Rockies Learn this in 60 seconds Key facts, context, and what it means, in one minute. Key takeaways Lawrence Berkeley and NREL have released a new county-level energy demand dataset through 2050. $67 million in funding has been deployed by the DOE's BTO for 2024 R&D. The initiative aims to help operators plan better for future building energy demands. A retrofit approach tested in a 184-unit multifamily building cut up-front electrification costs by 33% to 54% compared to standard methods. That single figure, published by the U.S. Department of Energy as part of its 2024 Building Technologies Office recap, illustrates the scale of the operational opportunity now in front of energy and facilities teams managing large real estate portfolios. More than $67 million in BTO funding deployed in 2024. The DOE's Building Technologies Office directed its 2024 investments across five major programs. The largest was the Building Energy Efficiency Frontiers and Innovation Technologies program, known as BENEFIT, which committed $38.8 million across 25 projects in 17 states. According to the Department of Energy, the combined BENEFIT cohorts from 2022, 2023, and 2024 carry a potential $40 billion in annual energy cost savings, assuming at least one project per technology area reaches mass adoption. The BENEFIT focus areas span next-generation building envelope systems, lighting, and HVAC, the three end uses that consistently dominate commercial and multifamily energy spend. For procurement and facilities directors evaluating which technologies to pilot, the 25-project portfolio represents a useful forward indicator of what will be commercially available in the next three to five years. BTO also pushed $6.5 million through its Small Business Innovation Research and Small Business Technology Transfer programs, funding 18 projects across 13 states in two separate award rounds, per the Department of Energy. An additional $2.4 million funded the Equitable and Affordable Solutions to Electrification prize, where the multifamily retrofit benchmark emerged. The Buildings Upgrade Prize, at $22 million, rounded out the major allocations, with 45 winners across 32 states selected in Phase 1 alone. A new dataset gives planners county-level demand visibility through 2050. On the planning side, researchers from Lawrence Berkeley National Laboratory and the National Laboratory of the Rockies published the Buildings Sector Scenarios dataset in Nature this year. The dataset, funded by BTO, provides hourly electricity demand projections at the county level across the entire contiguous United States through 2050, segmented by sector and end use. Non-electric fuel projections are also included at the state and annual level. The paper's authors, led by Jared Langevin of Lawrence Berkeley's Building and Industrial Energy Systems Division, describe the dataset as a response to high uncertainty in U.S. energy load growth, its effects on generation mix, and the downstream impact on customer costs. The dataset is designed to be customizable, letting utilities, grid operators, and large commercial energy buyers build their own scenarios rather than relying on a single forecast. For grid-connected facility operators, the practical value is in the hourly county-level resolution. That granularity supports site-specific analysis of peak demand exposure, a direct input to demand charge management strategies and onsite storage sizing decisions. The researchers validated the dataset against historical surveys and existing projected estimates of buildings sector demand, according to Nature. What the data and funding pipeline mean for operators today. The convergence of active federal R&D investment and a new public planning dataset shifts the operational calculus for energy and facilities teams. BENEFIT-funded technologies entering commercialization over the next several years will arrive in a market where utilities and grid planners are already using county-level scenario data. Operators who align their retrofit and electrification roadmaps with those same datasets will be better positioned in utility incentive programs and rate negotiations. The multifamily cost benchmark from the EAS-E prize is worth examining directly. A 33% to 54% reduction in up-front retrofit costs, demonstrated in a real 184-unit building and published by the Department of Energy, gives portfolio managers a credible reference point when building business cases for building-wide electrification. Most financial models for electrification retrofits have used rough estimates; this benchmark is based on an actual demonstrated approach. The Buildings Sector Scenarios dataset is publicly accessible and reproducible, per Nature, meaning operations teams with analytical capacity can run custom projections for their specific geographies and building types without waiting on utility-provided forecasts. Lawrence Berkeley and the National Laboratory of the Rockies also documented the full analysis workflow, which lowers the barrier for in-house energy analysts to adapt the tool. Featured companies The MarketScale Newsroom reports on the companies, technologies, and trends shaping 16 B2B industries. It turns primary sources and expert commentary into clear, useful coverage for the people doing the work.
Switch Automation has released new capabilities in its OpX software, developed with Lawrence Berkeley National Laboratory, advancing smart buildings from analytics to autonomous operations. Research shows buildings can achieve up to 29% energy savings through automated fault correction and control optimisation, compared to 9% from conventional analytics platforms. The collaboration demonstrated these advances through a programme with Cushman & Wakefield across six US commercial properties, delivering energy savings exceeding 10% and more than $290,000 in annual cost reductions. The technology integrates data across building systems using a semantically enriched data layer, enabling rapid deployment without requiring changes to underlying building automation systems. Switch Automation contributes to industry initiatives including the Brick ontology, supporting improved data interoperability and standardisation in building management.
Berkeley Lab and NVIDIA accelerate US leadership in hybrid quantum-classical computing. March 18, 2026 Press play to listen to this content March 18, 2026 - Today's state-of-the-art quantum computers rely on powerful classical high-performance computers for control, calibration, and error correction. As quantum processing units (QPUs) grow from dozens to thousands of qubits, the real-time measurement and processing demands placed on classical central processing units (CPUs) spike. This pressure is intensified because quantum states are sensitive to their environment, typically lasting less than a few milliseconds, placing even greater strain on the already extremely tight feedback loop between the quantum and classical systems. Berkeley Lab's QubiC (Quantum bit Controller) at AQT with NVIDIA DGX Spark and NVIDIA NVQLink. Credit: Keegan Houser / UC Berkeley. A new collaboration between Lawrence Berkeley National Laboratory (Berkeley Lab) and NVIDIA, announced in October 2025, is working to overcome key challenges in hybrid quantum-classical computing. Its goal is to enable QPUs and graphics processing units (GPUs) to operate together in real time, with shorter delays (latency) and far greater data throughput (bandwidth). The interdisciplinary research team at Berkeley Lab has successfully connected the lab's quantum control stack for QPUs, QubiC (Quantum bit Controller), to NVIDIA DGX Spark GPU using the NVIDIA NVQLink platform for low-latency, high-bandwidth GPU-QPU communication. Hardware testing is expected to conclude in early March, positioning the collaboration for cutting-edge AI-enhanced quantum experiments that will continue to advance the nation's leadership in scientific discovery and innovation. An Open Quantum-GPU Computing Workflow Funded by the U.S. Department of Energy Office of Science, QubiC is an open-source control and measurement system that has been deployed and tested at Berkeley Lab's Advanced Quantum Testbed (AQT) by users from national labs, universities, and industry. Inspired by Berkeley Lab's expertise in controls for particle accelerators, and supported in part by the Quantum Systems Accelerator, QubiC's modular framework allows quantum and classical workflow components to be replaced or modified independently. QubiC's open design philosophy has enabled seamless integration with the NVIDIA NVQLink open system architecture, coupling AQT's QPU with the NVIDIA DGX Spark. This tightly integrated quantum-classical architecture at AQT facilitates high-bandwidth, low-latency data exchange needed for real-time quantum computing controls. Using a high-speed 100-gigabit networking link, quantum data can flow directly from the QPU to GPU memory with minimal CPU involvement, significantly reducing latency. This efficient feedback loop enables the NVIDIA DGX Spark GPU to analyze results in real time and send updated instructions to the quantum hardware. To push this hybrid architecture even further, the AQT team is integrating NVIDIA's high-speed networking technology, Hololink IP, into the QubiC gateware to accelerate quantum workloads with classical supercomputing. "This integration milestone at AQT demonstrates a future where GPUs participate directly in real-time quantum control, enabling researchers to run experiments and error-correction workloads on the same GPU-based platforms used for modern AI and high-performance computing," explained Yilun Xu, a research scientist in Berkeley Lab's Accelerator Technology & Applied Physics (ATAP) Division and co-principal investigator of QubiC. The Road to AI-Enhanced Quantum Control Novel quantum experiments at AQT increasingly demand rapid decisions using classical hardware. To meet the broader scientific community's evolving needs, the QubiC team will continue supporting cutting-edge research through open access and collaboration with industry, academia, and national laboratories. By open-sourcing the QubiC design early in its development and throughout its integration with industry hardware such as NVIDIA accelerated computing, the Berkeley Lab team hopes that other quantum hardware groups will explore GPU-accelerated hybrid quantum-classical workflows. "By using high-performance networking technologies rather than custom, one-off connections, quantum researchers can scale the approach from a single testbed to large orchestrated systems where a single GPU system can coordinate multiple quantum control boards and experiments using familiar supercomputing tools," said Gang Huang, key investigator to the development of QubiC and ATAP staff scientist. Building on the need to integrate quantum computers with classical supercomputers, the next frontier in quantum control is to harness AI. This emerging phase in AI-enhanced quantum control can pave the way beyond small quantum prototype systems with dozens or hundreds of physical qubits toward large-scale quantum computers built from error-corrected logical qubits. The QubiC team at AQT will continue exploring AI-enhanced quantum control by deploying pre-trained neural network models on the NVIDIA DGX Spark. In particular, they plan to investigate applications such as readout classification, gate tuning, and real-time error correction decoding. They will also test new hybrid quantum-classical algorithms and adaptive techniques to improve quantum computing performance. Through support from the DOE Office of Science, Berkeley Lab's collaboration with NVIDIA advances quantum-classical research to enable next-generation discovery. By uniting national laboratory expertise with leading industry capabilities, the collaboration reinforces U.S. leadership in scalable, AI-driven computing. This effort aligns with the goals of the DOE Genesis Mission, which seeks to integrate AI, high-performance computing, and quantum technologies to accelerate the productivity and impact of American innovation. "Quantum processors are working hand-in-hand with state-of-the-art accelerated computing through the low latency and high throughput connectivity provided by the NVIDIA NVQLink platform," said Tim Costa, Vice President and General Manager for Quantum, NVIDIA. "By using NVQLink to run real-time workloads between quantum processors and GPUs, Berkeley Lab is performing the groundwork needed to turn today's supercomputing systems into tomorrow's quantum-GPU supercomputers." About Computing Sciences at Berkeley Lab High performance computing plays a critical role in scientific discovery. Researchers increasingly rely on advances in computer science, mathematics, computational science, data science, and large-scale computing and networking to increase our understanding of ourselves, our planet, and our universe. Berkeley Lab's Computing Sciences Area researches, develops, and deploys new foundations, tools, and technologies to meet these needs and to advance research across a broad range of scientific disciplines. Breakthroughs in Quantum Cryptography and Quantum Teleportation Redefined Secure Communication and Computing NEW YORK, March... SAN JOSE, Calif., March 18, 2026 - DDN has announced the launch of DDN Horizon,... RICHLAND, Wash., March 18, 2026 - Open-source graphics processing unit (GPU) acceleration is coming to quantum-classical... ELMSFORD, N.Y., March 18, 2026 - SEEQC today announced a significant advancement in the development of... CHICAGO, March 18, 2026 - memQ, an industry leader in quantum networking solutions for distributed... SAN JOSE, Calif., March 18, 2026 - Super Micro Computer, Inc. is announcing new additions...
Berkeley Lab team helps develop 'AQuaRef' ai-quantum approach for protein structure modeling. March 11, 2026 Press play to listen to this content March 11, 2026 - Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational chemistry, is not unlike using the Rosetta Stone to unlock the secrets of ancient Egyptian texts. Once a protein's structure has been discovered, or defined, one can infer crucial information about its function or, in a diseased state, its dysfunction. While researchers have been pursuing the quest of solving protein structure for decades, advancing tools and computing technologies offer a new frontier for this work. A collaborative study recently published in Nature Communications unveiled a new computing program that offers a faster and more accurate way to determine protein structure at a new level of precision. Researchers from the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), along with an international team of researchers, were a part of the effort. This tool, dubbed AI-enabled Quantum Refinement, or AQuaRef for short, uses quantum-mechanical calculations (QM) and artificial intelligence (AI) to predict the highly-accurate placement of atoms and electrons to determine a protein's molecular structure. This program is a part of Phenix, a comprehensive software suite that generates realistic computer models used by structural biologists around the world to solve macromolecular structures. "We're all basically a bunch of proteins," said Nigel Moriarty, a Berkeley Lab researcher and contributor to the recent publication. "They do so much in our bodies that detail the processes of life. Understanding their structure can give us insights into the mechanisms that cause disease in humans or produce energy in plants. All of this knowledge can lead to more effective therapeutics and bioenergy production." The current way of mapping a protein's structure entails bringing together two streams of information: experimental data produced through techniques like X-ray crystallography and cryogenic electron microscopy (cryo-EM), and theoretical data that exists in a library of detailed, known protein structural information. But the current options are limited, explained Moriarty, a computational research scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division's Phenix group. Our understanding today is limited to the chemical entities that have already been defined and doesn't yet include meaningful noncovalent interactions, the type of attraction typically seen holding a protein in its structural form. "That's where quantum and AI come in," he said. Nearly five years ago, members of the Phenix team began working with researchers at Carnegie Mellon University to explore how they might be able to apply their coding work to Phenix's offerings. The collaborative approach, coupled with 15 years of incremental research, led to this breakthrough program. In addition to Moriarty, other members of the Phenix team involved in this work were Paul Adams and Billy Poon, with Pavel Afonine leading the research. AQuaRef uses machine learning (ML) tools developed at Carnegie Mellon integrated with the Phenix software to compute energy and forces for scientifically interesting proteins - making quantum-level refinement practical where it was previously impossible. Of the 71 experiments that were tested in this study, AQuaRef produced higher quality structural information at a substantially lower computational cost while maintaining an equal or better fit to experimental data. In addition to the proof-of-concept results from this work, AQuaRef also correctly determined proton positions in DJ-1, a human protein linked to some forms of Parkinson's Disease, the structure of which has been notoriously difficult to map. Now that the team has confirmed that quantum-level refinement of a 3D protein model structure is possible, they're aiming to broaden the scope to include more diverse structures, such as those required for pharmaceutical drug design. And the potential impacts of this work reach far beyond human health, from better understanding the mechanisms of photosynthesis for enhanced crop productivity to mapping the proteins in plants as it relates to biofuel production. "There is a near-infinite number of things that can benefit from a detailed understanding of these mechanisms and protein structure," said Moriarty. "I'm excited to see how the paradigm shift that AQuaRef represents impacts the field of protein structure determination." This international team also included collaborators from the University of Wrocław, Poland, the University of Florida, and Pending.AI, Australia. This work was funded by the National Institutes of Health as well as with support from the Phenix Industrial Consortium. WASHINGTON, March 11, 2026 - Siemens today announced it has signed a Memorandum of Understanding (MOU)... Deep Engineering Collaboration on AI Factories, Powering Inference and Agentic AI, Enables Nebius to Deploy... ESPOO, Finland, March 11, 2026 - IQM Quantum Computers today announced the launch of Aalto Q20... TORONTO and DAEJEON, South Korea, March 11, 2026 - Xanadu Quantum Technologies Inc., a leading... Partnership expands IonQ's UK presence, accelerates IP generation, brings IonQ's world-class quantum networking capabilities, and... LOUISVILLE, Colo., March 11, 2026 - Infleqtion, a global leader in quantum computing and quantum sensing...
Berkeley Lab: 2026 CSA symposium helps researchers amplify their scientific impact. February 23, 2026 Press play to listen to this content Feb. 23, 2026 - This month, 13 early-career researchers from Berkeley Lab Computing Sciences Area (CSA) presented their work at the 2026 Postdoc Symposium, an event focused on articulating the real-world impact of their discoveries. More than just a showcase, the annual symposium is a launchpad for the next generation of scientific leaders. Through weeks of intensive coaching from CSA staff, participants hone their presentation skills and leave equipped with a professional recording of their talk to share with future employers. Since its inception in 2020, the program has helped shape 134 presentations, solidifying its role as a vital training ground for early-career researchers. "Our postdoctoral researchers represent the future of scientific innovation, and the CSA Postdoc Symposium is one of our most direct and impactful investments in their success. This program provides a unique platform not only to share their work but also to receive expert coaching and feedback that cultivates the essential communication skills they need to become leaders in their fields. These are the skills that will help them secure funding, build collaborations, and translate discovery into real-world solutions," said Stefan Wild, Director of Berkeley Lab's Applied Mathematics and Computational Research Division and a key champion of the program. Many of this year's participants echoed the value of the program: Alec Decktor "Having participated before, I knew the Postdoc Symposium was a fantastic event and the perfect venue to communicate my research progress to a broad Berkeley Lab audience. It's excellent practice for giving a non-technical talk - an invaluable skill for any scientist - and a great networking event. The connections I've made have led to exciting new research opportunities. "What makes the symposium unique is the opportunity to receive extremely valuable feedback on your presentation from senior scientists across different fields. This has directly helped me develop my ability to prepare talks for other conferences. To anyone who might be hesitant, I'd say the environment is incredibly supportive. The work you put in pays off directly; I've reused slides I created for the symposium in several other presentations. It's well worth the time and a great opportunity to develop yourself as an early-career scientist," said Alec Dektor, a postdoctoral researcher in Berkeley Lab's Scalable Solvers Group. Durga Mandarapu "The symposium process fundamentally changed how I approach presentations. The feedback from Lab leadership and communication experts was invaluable, and it helped me rethink how to design slides - for instance, learning to use the title to state the key takeaway instead of just a topic. That kind of clarity has a direct impact. When I later reached out to a Division Deputy who had provided feedback, he already had a clear understanding of my skills and research from the symposium. That familiarity made it much easier to identify opportunities for collaboration. It showed me that our work has more impact when people truly understand it, and this is the perfect place to learn that skill," said Durga Mandarapu, a postdoctoral researcher in Berkeley Lab's AMCR. Navjot Singh "What sets this symposium apart is that you're presenting to experts from a wide range of scientific disciplines, not just specialists in your own field. The feedback I received on how people outside my immediate area perceive certain concepts was invaluable - that's a perspective you don't easily get within your own research group. Learning to adjust my slides and delivery for that audience is a critical skill. It's an investment in one of the most important qualities of a successful scientist: the ability to communicate your work effectively across disciplinary boundaries," said Navjot Sing, a postdoctoral researcher in Berkeley Lab's AMCR. Alex Morehead "After seeing recordings of past events, I was convinced of the value of sharing my research at the Postdoc Symposium. The process of revising and presenting my research presentation has given me more confidence and knowledge for future presentations. The tight-knit community here at Berkeley Lab makes it an incredible place to connect with researchers interested in similar topics and gather relevant, valuable feedback. I'd encourage everyone to seriously consider it - practicing your presentation skills is a great long-term investment for any career," said Alex Morehead, 2025 Hopper Postdoctoral Fellow at NERSC. Shubhabrata Mukherjee "What makes the Postdoc Symposium so unique is how supportive and well-structured the entire experience is. The focus isn't just on presenting results; it's on helping you translate technically deep work for a broad audience in a collaborative environment. Condensing my research in AI and scientific data analysis clarified my thinking and built new collaborations across the Lab. It's a fantastic opportunity to gain confidence and practice a skill essential for any interdisciplinary career," said Shubhabrata Mukherjee, a Machine Learning Postdoctoral Fellow in AMCR. Nabin Giri "The symposium is an excellent experiential learning opportunity. The feedback from organizers and peers was incredibly helpful, teaching me to communicate my work with clarity and impact. It's the perfect preparation for job interviews and conferences because it gives you a safe space to practice the kind of communication that is essential for your career. The networking was terrific, and I made great connections and friends across the Lab," said Nabin Giri, a postdoctoral researcher in Berkeley Lab's Scientific Data Division (SciData), who is working on applying AI to structural biology. About Computing Sciences at Berkeley Lab High performance computing plays a critical role in scientific discovery. Researchers increasingly rely on advances in computer science, mathematics, computational science, data science, and large-scale computing and networking to increase our understanding of ourselves, our planet, and our universe. Berkeley Lab's Computing Sciences Area researches, develops, and deploys new foundations, tools, and technologies to meet these needs and to advance research across a broad range of scientific disciplines. 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