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Neuroscience Biology Lead

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Manifold Bio

Manifold Bio

11-50 employees

High-throughput in vivo drug design platform



Remote in USA

Computational Biology
Biology Lab & Research
Biology & Biotech
  • Biology Ph.D. or equivalent experience
  • Experience designing screening funnels leveraging both in vitro and in vivo assays with a focus on biologics (5-10 years for Dir. level; 10+ years for VP level)
  • Previous experience as a team lead or co-lead in an industry setting
  • Experience with hybrid drug discovery models blending external and internal R&D workflows
  • Highly independent and proactive, excellent communication and cross-functional team coordination skills
  • Guide company level neuroscience / CNS strategy
  • Evaluate new project/target opportunities and propose POC experiments
  • Leverage external resources and coordinate internal team members to lead projects from discovery to candidate selection
  • Coordinate with protein engineering on binder discovery and/or evaluate in-licensing opportunities, considering tradeoffs among target presentation and relation to disease biology
  • Design screening funnels that integrate our novel mDesign in vivo biologics design platform
  • Analyze and interpret data to enable decision making
  • Design development plans to early human PoC, including specifying DC nomination criteria

Manifold Bio is a pioneering company in the field of precision biologics engineering through its innovative mDesign™ Platform, which features mCodes™ technology. This platform facilitates a novel approach to pooled in vivo testing of complex biologics, propelling advancements in therapeutic development across multiple areas. The company's focus on cutting-edge molecular biology and a culture of pushing the boundaries of drug design technology makes it a promising place for professionals passionate about transformative healthcare solutions.

Company Stage

Series A

Total Funding



Boston, Massachusetts



Growth & Insights

6 month growth


1 year growth


2 year growth