Director/Sr. Director
Biochemical and Cellular Pharmacology
Posted on 9/11/2023
Scorpion Therapeutics

51-200 employees

Company Stage


Total Funding





Boston, Massachusetts

Growth & Insights

6 month growth


1 year growth


2 year growth

San Francisco, CA, USA
Experience Level
Biology & Biotech
  • Ph.D. in relevant field with 10+ years of industry experience
  • Strong background in biochemistry, molecular biology, and cell biology, and experience in early drug discovery
  • A deep and broad understanding of the development, validation & execution of a wide array of binding & biochemical/cellular functional assays such as AlphaLISA, TR-FRET/HTRF, ELISA, NanoBRET, FP, SPR, MST and DSF
  • High technical proficiency in implementing protocols for multi-modal plate readers (e.g., Envision, Neo, PHERAstar), liquid handlers (e.g., Multidrop Combi, Echo acoustic dispensers, digital dispensers) & other automated laboratory equipments (e.g., stackers/plate hotels, robotic arms, incubators, etc.)
  • Expertise in handling, analyzing and visualizing large data sets coming out of screening assays
  • Direct experience in working with and characterizing challenging proteins
  • Ability to provide expert knowledge on the biochemical mechanisms of small molecule interactions with protein targets of interest
  • A strong record of achievement, including contributing to drug discovery programs and publications in high-impact journals
  • Commitment to the highest-quality research with outstanding organizational abilities and scientific execution
  • Outstanding decision making, organizational and analytical skills
  • Exceptional interpersonal and communication skills
  • Lead a team of scientists and RAs in the design, development, validation, and implementation of novel biochemical/biophysical and cellular assays for the identification, profiling, and mechanistic characterization of small molecule compounds
  • Develop sensitive and robust biochemical and cell-based assays and translate proof-of-concept assays into high-quality, microtiter plate-assays that have been optimized & validated to meet predefined standards of performance
  • Manage external FTEs and troubleshoots methods at CROs, for compound library screenings and weekly assays
  • QC and analyze data & document all findings & discoveries in an electronic lab notebook in a timely manner
  • Work collaboratively with colleagues in biology, chemical biology, informatics, structural biology and medicinal chemistry to define and develop screening cascades for Scorpion's novel targets, advancing programs from early hit-finding through candidate selection
  • Contribute to multiple projects simultaneously and manage diverse team interactions
  • Proactively communicate strategy, critical issues, and recommendations to enable appropriate resource decisions
  • Maintain excellent communication across internal and external colleagues