The Company

Verve is a clinical-stage genetic medicines company established with a mission to solve the global health epidemic of cardiovascular disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, Verve is pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company’s initial three programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease. VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat atherosclerotic cardiovascular disease (ASCVD) patients not at goal on oral therapy. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and ultimately to treat patients with refractory hypercholesterolemia. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.

The Position

Verve is seeking an experienced Senior Clinical Scientist to join our team as we continue to advance gene editing medicines for cardiovascular disease into clinical development. In this position, you will be an integral part of the clinical development team supporting the execution of early phase clinical studies. You will report to the Senior Director, Clinical Research. The ideal candidate will have outstanding communication skills, attention to detail, and the ability to thrive independently in a highly innovative and fast paced environment.

Job Responsibilities

Partners with other clinical scientists and medical monitor on oversight of clinical trial activities, including safety reviews and site interactions
Organize and lead process for review of potential patients for study participation
Review, analyze, and interpret emerging clinical trial data
Liase with the broader clinical development team at Verve (clinical operations, data management, and regulatory teams)
Contribute to authoring key study and regulatory documents (e.g. protocol, ICF, study manuals)
Leads internal meetings to review topics and develop mitigation plans
Contribute to the development of presentations emerging from clinical studies
Ensure compliance of all activities with ICH/GCP guidelines, applicable regulatory requirements, and Verve SOPs
Other duties as assigned

Qualifications

Advanced degree in life sciences (e.g. PhD, PharmD, MD, Masters etc.) with 5+ years of relevant experience including 3 years of clinical development experience
Familiarity with key clinical study documents
Experience with analysis and review of clinical data
Working knowledge of biostatistics, GCP, and regulatory requirements for clinical studies
Experience working with CROs and external vendors
Strong attention to detail and organizational skills
Exceptional verbal and written communication skills
Ability to build strong relationships and work effectively with cross-functional teams

Don’t check off every box in the requirements listed above? Please consider applying anyway. We want the best candidates for the job, and those candidates don’t always meet 100% of the qualifications listed. At Verve, we are dedicated to building diverse and inclusive teams who embody the values we share: grit, spirit, drive, and passion. We look forward to learning more about your unique background.

EEO Statement

Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & Staffing Agencies

Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.

The Company

The Position

Job Responsibilities

Qualifications

EEO Statement

Recruitment & Staffing Agencies

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