Full-Time

Director – Clinical Outsourcing

Confirmed live in the last 24 hours

Pliant Therapeutics

Pliant Therapeutics

51-200 employees

Develops treatments for fibrotic diseases

Biotechnology
Healthcare

Compensation Overview

$220k - $230kAnnually

Senior, Expert

San Bruno, CA, USA

Hybrid position requiring 3 days/week at Pliant in South San Francisco.

Category
Healthcare Administration & Support
Medical, Clinical & Veterinary
Required Skills
Excel/Numbers/Sheets
Requirements
  • 12+ years of relevant clinical development experience preferred with a B.A./B.S. degree; or 10+ years of relevant clinical development experience preferred with an advanced degree.
  • 3+ years of experience directly negotiating full scope CRO agreements at task and resource by region level and/or building CRO resourcing models.
  • 2+ years people management experience preferred.
  • Ability to utilize complex Microsoft Excel formulas and functions – e.g. VLOOKUP, INDEX, MATCH and pivots.
  • Experience with writing macros or other programming languages a plus.
  • Pliant requires all new hires to be fully vaccinated prior to the first date of employment (subject to any legally required exemptions).
Responsibilities
  • Proactively developing and maintaining the standards, processes and tools utilized by Business Operations.
  • Leading the vendor selection lifecycle including Request-for-Information (RFI) and/or Request-for-Proposal (RFP) activities for clinical services such as study management (CROs), central laboratory, bioanalytical services, interactive response technology (IRT), etc.
  • Leading the review and negotiation of budgets for CRO, central laboratory and other vendor agreements on behalf of Clinical Development.
  • In collaboration with Legal, negotiating vendor agreements including payment terms in accordance with Pliant standards and processes.
  • Developing site (investigator grant) budget templates in accordance with Pliant’s fair-market value standards.
  • Supporting the quarterly financial reviews with Clinical Operations and Corporate Finance.
  • Leading the budget forecasting activities for the Development organization during biannual Corporate budget planning cycles.
  • Effectively partnering with relevant internal and external stakeholders such as Clinical Operations, Legal, Regulatory, Finance, Quality Assurance and/or vendors, as applicable, to enable informed, risk-considered decisions.
  • Willingness to mentor or manage other Business Operations professionals based on business need.

Pliant Therapeutics develops treatments for fibrotic diseases, which cause thickening and scarring of connective tissue, leading to organ dysfunction. Their products work by targeting the biological mechanisms behind fibrosis, particularly through the inhibition of integrins, which are proteins that help cells stick together and communicate. This targeted approach allows Pliant to create effective treatments for various fibrotic conditions. Unlike many competitors, Pliant focuses specifically on the science of fibrosis and integrin biology, aiming to reverse the effects of these diseases rather than just manage symptoms. The company's goal is to halt the progression of fibrotic diseases and restore normal organ function, ultimately improving the quality of life for patients.

Company Stage

IPO

Total Funding

$694.9M

Headquarters

San Francisco, California

Founded

2015

Growth & Insights
Headcount

6 month growth

6%

1 year growth

12%

2 year growth

54%
Simplify Jobs

Simplify's Take

What believers are saying

  • Pliant's accelerated development of bexotegrast for IPF and positive Phase 2a trial results indicate strong potential for successful market entry.
  • The company's participation in high-profile investor events and scientific congresses enhances its visibility and credibility in the biotech community.
  • Recent strategic appointments, including a new Chief Development Officer and Chief Regulatory Officer, bolster Pliant's leadership team and operational capabilities.

What critics are saying

  • The high costs and long timelines associated with drug development pose financial risks, especially if clinical trials do not meet endpoints.
  • The competitive landscape in biopharmaceuticals, particularly in fibrosis treatment, requires Pliant to continuously innovate to maintain its edge.

What makes Pliant Therapeutics unique

  • Pliant Therapeutics focuses specifically on fibrotic diseases, leveraging deep expertise in fibrosis and integrin biology, unlike competitors with broader therapeutic areas.
  • Their targeted approach to integrin inhibition offers a unique mechanism of action that sets them apart from other fibrosis treatments.
  • Pliant's commitment to rigorous clinical trials and data-driven development ensures high standards of efficacy and safety, distinguishing them in the biopharmaceutical market.

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