Associate Director – Sr. Medical Science Liaison

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
 
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. 
 
Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

Affiliate Overview

Calcilytix Therapeutics, an affiliate within BridgeBio Pharma, is developing encaleret, a negative allosteric modulator of the calcium-sensing receptor (CaSR) for the treatment of Autosomal Dominant Hypocalcemia Type 1 (ADH1), a genetic cause of hypoparathyroidism. Encaleret is currently being evaluated in a Phase 3 clinical study and has received Orphan Drug Designation from the US FDA, EMA, and PMDA as well as Fast Track Designation from the US FDA. Results from the Phase 2b clinical study of encaleret in patients in ADH1 were published in the New England Journal of Medicine.

What You'll Do

The Associate Director, Sr. Medical Science Liaison (Sr. MSL) is responsible for cultivating strong scientific relationships with external experts, delivering clinical and scientific insights, and serving as a strategic partner to both internal teams and the broader medical community. We are looking for an individual who thrives in dynamic environments and is known for their persistence, resourcefulness, and commitment to excellence.

With a strong scientific background and a passion for supporting those with rare diseases, the Sr. MSL will build trusted partnerships with key opinion leaders (KOLs), facilitate scientific exchange, and collaborate cross-functionally to advance internal initiatives. The role is critical in supporting strategy through targeted patient identification efforts. By engaging with healthcare professionals (HCPs), the Sr. MSL helps drive earlier diagnosis and appropriate patient referrals.

This role offers the opportunity to step beyond traditional field-based responsibilities, with the ability to shape and drive medical affairs tactics and operations from the ground up. The Sr. MSL will play an important role in advancing internal initiatives and externally engaging with thought-leaders in the areas of endocrinology, nephrology, and genetics.

Responsibilities

• Identify and engage with clinicians who may be managing undiagnosed or misdiagnosed patients, with the goal of increasing diagnostic recognition and appropriate referrals
• Advance clinical practice and improve patient outcomes by engaging key stakeholders across the assigned territory
• Cultivate strong professional relationships with KOLs and influential HCPs to support scientific exchange and medical collaboration
• Serve as a scientific resource and strategic partner to HCPs to support patient identification and appropriate care pathways
• Establish and maintain professional relationships with a range of HCPs – including physicians, pharmacists, nurses, and other medical experts – to support disease education, product awareness, and evidence-based practice in alignment with medical strategy
• Conduct impactful customer engagements, including discussions around emerging data, clinical trial activity, treatment barriers, market dynamics, unmet medical needs, pipeline updates, and disease state education
• Provide medical and scientific support for internal cross-functional teams, including clinical development and commercial, helping to ensure alignment with external insights and evolving scientific landscapes
• Participate in the planning and execution of advisory boards, speaker training programs, and medical education initiatives
• Support investigator-initiated research efforts and collaborate on the development of scientific publications and congress presentations
• Serve as a medical and scientific expert at major medical conferences, symposia, and external stakeholder meetings
• Collect, synthesize, and relay field-based insights to internal teams to inform clinical strategy, product development, and evidence generation plans
• Identify opportunities to connect KOLs with appropriate BridgeBio colleagues and follow through to support ongoing collaboration and alignment
• Ensure compliance with all internal policies and external regulatory requirements, including company travel and expense policies, institutional guidelines, and applicable local, state, and federal laws
• Operate in full accordance with company Ethics, Compliance, and Promotional policies, fostering a culture of accountability and integrity among peers and collaborators

Where You'll Work

This is a U.S.-based remote role that will require travel as needed for visits to our San Francisco Office and medical conferences within the United States. The territory may be adjusted in the future based on the candidate’s location—national travel will be required in the interim.

Who You Are

• Advanced degree required (MD, DO, PharmD, or PhD)
• Relevant Experience
  • Minimum 2 years of experience in Medical Affairs
  • Prior experience as an MSL is required; rare disease experience is a plus
  • Background in endocrinology, nephrology, or genetics
• Skills
  • Excellent scientific communication and presentation skills
  • Ability to ideate and execute strategy quickly and independently
  • Comfortable working cross-functionally in a fast-paced environment
  • Strong organizational, analytical, and interpersonal abilities
  • Self-driven with high emotional intelligence and professional maturity
• Other Requirements
  • Ability to comply with all internal policies and external regulations, including those related to travel, expenses, and compliance
• Travel required: ~85% travel, including territory field visits and U.S.-based medical conferences
  • Preference will be given to candidates based in a major metropolitan area with convenient access to a major airport

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. 

Financial Benefits:

• Market leading compensation 
• 401K with 100% employer match on first 3% & 50% on the next 2%
• Employee stock purchase program
• Pre-tax commuter benefits
• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents
• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
• Hybrid work model - employees have the autonomy in where and how they do their work 
• Unlimited flexible paid time off - take the time that you need
• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
• Flex spending accounts & company-provided group term life & disability 
• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities