Full-Time
Production Scientist
Posted on 8/6/2024
Synthego
201-500 employees
Provides synthetic RNA and gene editing tools
Compensation Overview
$110k - $130kAnnually
Mid, Senior
San Carlos, CA, USA
- PhD in Chemistry, Chemical Engineering, or Biotechnology with at least 1 year of experience, or MS in Chemistry, Chemical Engineering, or Biotechnology with 4 years experience in clinical or pre-clinical manufacturing operations or equivalent.
- Strong understanding of operational processes, quality management systems, and regulatory compliance (e.g., ISO, cGMP), with experience authoring NCRs, CAPAs, CHGs, Qualification protocols (IQ, OQ, PQ, PPQ), and Validation reports.
- Excellent problem-solving skills with a proven track record of efficiently taking ownership of troubleshooting and resolving manufacturing process issues.
- Ability to work cross-functionally with teams in commercial, R&D, quality assurance, quality control, and supply chain to develop and implement innovative solutions.
- Strong leadership and communication skills, with experience managing and mentoring teams.
- Develop and optimize production processes to meet customer requirements and quality standards, documenting these processes in Synthego’s system to ensure consistency and repeatability.
- Take ownership of manufacturing process troubleshooting, establishing a response cascade to address and resolve issues efficiently.
- Champion Operations Excellence & Continuous Improvement (Kaizen) efforts to tackle process inefficiencies and cost reduction challenges, with progress tracked on an existing continuous improvement board.
- Acquire and apply knowledge of end-to-end oligonucleotide synthesis and purification in ISO clean rooms to produce preclinical and clinical-grade sgRNA orders.
- Operate complex scientific instrumentation for oligonucleotide synthesis and purification, effectively interpreting LC/MS data.
- Collaborate with cross-functional teams—including science, engineering, marketing, R&D, quality assurance, quality control, and supply chain—to develop and implement innovative solutions that exceed customer expectations and align production goals with company objectives.
- Lead the development and training of research associates, production specialists, and associate scientists to build a skilled and knowledgeable team.
Synthego specializes in biotechnology, focusing on genetic engineering by providing synthetic RNA and gene editing tools. Their products enable scientists to modify genes, which can lead to advancements in disease treatment and agricultural improvements. Synthego serves a variety of clients, including research institutions, pharmaceutical companies, and biotech startups, who utilize their products for drug discovery, disease modeling, and genetic research. The company stands out in the growing genetic engineering market by offering a platform that grants users access to advanced gene editing capabilities, alongside their synthetic RNA products. Synthego's goal is to support and enhance genetic research and applications through their tools and services.
Company Stage
Series E
Total Funding
$459.7M
Headquarters
Menlo Park, California
Founded
2012
6 month growth
↓ -26%1 year growth
↓ -37%2 year growth
↓ -54%
Simplify's Take
What believers are saying
- Synthego's licensing agreement with HuidaGene for the hfCas12Max nuclease positions it at the forefront of CRISPR-based therapeutic applications.
- The addition of Dr. Bill Skarnes to the advisory board and the launch of high-throughput induced pluripotent stem cell genome engineering highlight Synthego's commitment to innovation and expertise.
- The opening of a new GMP synthesis facility and the launch of IND-enabling gRNAs bolster Synthego's support for the entire discovery-to-clinic continuum, enhancing its market position.
What critics are saying
- The rapid pace of innovation in the genetic engineering field requires Synthego to continuously advance its technologies to stay competitive.
- Leadership changes, such as the recent CEO transition, could lead to strategic shifts and potential instability within the company.
What makes Synthego unique
- Synthego's focus on synthetic RNA and advanced gene editing tools, such as the high-fidelity Cas12 CRISPR nuclease, sets it apart from competitors who may not offer such specialized products.
- The company's strategic partnerships, like those with HuidaGene and bit.bio, enhance its capabilities in developing next-generation CRISPR-based therapies and synthetic circuitry in cells.
- Synthego's state-of-the-art GMP manufacturing facility ensures high-quality production of CRISPR components, providing a competitive edge in the clinical development of gene editing therapies.
Benefits
Generous Equity Package
Medical, Dental & Vision
401(k) Plan
Catered to You
Fully Stocked
Transportation
Green Environment
Stay Fit
Legal Ease