Full-Time

Principal Scientist QSP

Confirmed live in the last 24 hours

Sanofi

Sanofi

10,001+ employees

Develops pharmaceuticals and life-saving vaccines

Biotechnology
Healthcare

Senior

Cambridge, MA, USA

This position is based in Cambridge, MA.

Category
Computational Biology
Biology Lab & Research
Biology & Biotech
Required Skills
R
Julia
MATLAB
Data Analysis
Requirements
  • PhD with an excellent track record of productivity in the areas of systems pharmacology/biology, computational biology, biomedical engineering or related field, as manifested by publications and scientific presentations in prestigious conferences (Ideally 2 years of experience)
  • Proficiency in mathematical modeling using differential equations and programming as demonstrated by hands-on experience in a variety of computational tools such as MATLAB, Julia and R (MATLAB preferred)
  • Strong commitment to on-the-job-training
  • Experience in drug discovery/development a plus, especially in quantitative aspects such as bioinformatics or pharmacometrics
  • Excellent oral and written communication skills
Responsibilities
  • Function as part of a team to develop and implement multiscale computational models of complex diseases based on detailed biological mechanistic knowledge.
  • Identify and leverage relevant preclinical and clinical data to incorporate into models.
  • Survey literature to gain understanding of critical physiological processes to be represented, and identify suitable mechanistic elements, data, parameters and assumptions to be included.
  • Analyze internal preclinical and clinical data to inform modeling activities.
  • Analyze simulation results and identify suitable strategies to resolve issues pertaining to model performance and accuracy.
  • Maintain extensive documentation of model development process, and data analysis.
  • Maintain quantitative systems pharmacology expertise through comprehensive education including attendance and participation in conferences, scientific workshops etc.
  • Communicate modeling predictions to key stakeholders.

Sanofi provides healthcare solutions through its pharmaceutical and biotechnology products, focusing on treatments and vaccines for various medical conditions. The company conducts extensive research and development to create new therapies and improve existing ones, particularly in areas like immunology, oncology, and rare diseases. Sanofi's products include prescription medicines, over-the-counter items, and vaccines, which are distributed to patients, healthcare professionals, and governments. What sets Sanofi apart from its competitors is its strong emphasis on scientific innovation and strategic partnerships, allowing it to maintain a diverse product pipeline and a global presence. The company's goal is to enhance health outcomes and improve the quality of life for individuals worldwide.

Company Stage

Grant

Total Funding

$2B

Headquarters

Paris, France

Founded

N/A

Growth & Insights
Headcount

6 month growth

0%

1 year growth

0%

2 year growth

0%
Simplify Jobs

Simplify's Take

What believers are saying

  • Sanofi's strong financial performance, as evidenced by its raised 2024 outlook, indicates robust growth and stability.
  • The company's strategic investments in innovative biotech firms, such as Ventyx Biosciences, enhance its pipeline and potential for breakthrough therapies.
  • Sanofi's Dupixent receiving a positive recommendation for expanded use in children demonstrates its leadership in addressing unmet medical needs.

What critics are saying

  • The highly competitive pharmaceutical market requires Sanofi to continuously innovate to maintain its market position.
  • Regulatory challenges in different regions could delay product approvals and impact revenue streams.

What makes Sanofi unique

  • Sanofi's extensive R&D efforts and strategic partnerships, such as with Orano Med for radioligand therapies, set it apart in the competitive pharmaceutical landscape.
  • The company's global reach and focus on patient-centric solutions allow it to effectively navigate diverse regulatory environments and deliver innovative treatments worldwide.
  • Sanofi's investment in sustainable initiatives, like SureChill's 'Cooling as a Service' model, highlights its commitment to addressing healthcare challenges in emerging markets.

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