Principal Program Manager

Who is Prescryptive?

Prescryptive is the healthcare technology company enabling the direct access marketplace for prescription drugs. Our platform aligns incentives so affordability, choice, and patient access become the natural outcome of a functioning system. Learn more about us by following us onLinkedInor visitingPrescryptive.com.

About this role

The Strategy Delivery team helps Prescryptive execute its highest-priority, cross-functional initiatives. We partner with leaders across the company to solve complex business problems, align teams around shared outcomes, and deliver lasting business impact.

As a Principal Program Manager, Strategy Delivery, you'll lead some of our most important initiatives, working across Product, Engineering, Commercial, Operations, and corporate functions. Whether launching new capabilities, improving how we operate, or supporting our next stage of growth, you'll create clarity where ambiguity exists, align diverse teams, and help turn strategic priorities into measurable business results. You'll rely on strong judgment, influence, and systems thinking to navigate complexity, thrive in a fast-moving environment, and lead enterprise execution at scale.

This role does not have direct people management responsibility. Instead, you'll lead through influence, earning trust across the organization, helping leaders make timely, informed decisions, and creating the structure and momentum needed to deliver successful outcomes. You'll also help strengthen how Prescryptive delivers its most important initiatives.

You'll thrive in this role if you enjoy solving difficult business problems, creating clarity where ambiguity exists, building alignment across diverse teams, and seeing complex initiatives through to meaningful business outcomes.

What you will do

• Lead multiple complex, cross-functional programs that advance Prescryptive's strategic priorities, from planning through successful delivery.
• Partner with executive sponsors and functional leaders to define governance, success measures, sequencing, accountability, and program scope.
• Build integrated program plans, coordinate work across teams, and proactively manage dependencies, risks, and competing priorities.
• Drive executive visibility by communicating progress, surfacing tradeoffs, recommending actions, and holding teams accountable while adapting plans as priorities evolve.
• Ensure programs deliver meaningful business outcomes, not simply completed project plans.
• Lead a portfolio of concurrent enterprise initiatives and help leaders balance priorities, dependencies, and resources across the work.
• Help strengthen how Prescryptive delivers its most important initiatives by improving program management practices, coaching and mentoring other program managers, and raising the consistency and effectiveness of enterprise execution

What you will bring (minimum requirements)

• Bachelor's degree required.
• 10+ years of experience leading large, complex, cross-functional programs that deliver measurable business outcomes.
• Experience partnering with senior leaders and executive sponsors to lead complex, cross-functional initiatives.
• Proven ability to lead through influence, build alignment, and drive execution across multiple teams.
• Strong program management skills, including planning, governance, risk and dependency management, and executive communication.
• Experience managing a portfolio of concurrent enterprise initiatives and balancing competing priorities.
• Experience succeeding in a growth-stage company or other fast-paced, evolving business environment.
• Experience leading enterprise technology, product, or business transformation programs.
• Strong judgment, communication skills, and the ability to thrive in a fast-paced, ambiguous environment.
• Experience using AI-enabled tools to improve planning, analysis, communication, or execution effectiveness.

Ideally you will also have

• Experience in healthcare, pharmacy, healthcare technology, or another regulated industry.
• Experience leading organizational transformation or large-scale business change initiatives.
• Experience partnering closely with Product and Engineering organizations delivering software or technology-based solutions.
• Experience improving program management practices or organizational execution capabilities.
• Familiarity with Smartsheet, Miro, Linear, or similar planning and collaboration tools.

What we have to offer

• The opportunity to grow alongside an early-stage company shaking up a big, old-fashioned industry
• Flexible time off, including 12 paid holidays
• 401k match plus 100% employer paid medical, dental, and vision
• Company contribution to Health Savings Account
• Stock options

Prescryptive is committed to fair pay practices. The projected annual salary for this position is $170,000 to $245,000. When preparing an offer, we consider the candidates resume, experience, interview feedback, internal equity, and location.

Prescryptive is an Equal Opportunity Employer. Prescryptive does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need.