Sr. Director

Translational Science

Confirmed live in the last 24 hours

Tarsus Pharamceuticals

Tarsus Pharamceuticals

201-500 employees

Develops therapeutics for eye conditions



Irvine, CA, USA

Required Skills
Data Analysis
  • MD (Ophthalmology) with a minimum 5+ years experience in the pharmaceutical industry or in a venture capital/entrepreneurial environment
  • PhD degree in pharmacology, cell biology or related field with 10+ years’ experience and a minimum of 6+ years in the pharmaceutical or industry setting
  • Proven project team leadership or a translational team member role in an industry setting for assets progressing through IND-enabling studies and/or Phase I/II trials
  • Superior knowledge and solid understanding of emerging research, mechanisms of action and disease models in anterior and posterior segment eye care diseases, preclinically and clinically
  • Knowledge of the clinical landscape in ophthalmology indications with good understanding of novel agents and impact to this landscape
  • Excellent oral and written communication skills, including writing, reviewing, and editing scientific documents
  • Superior interpersonal skills, diplomacy, and positive-influencing abilities
  • Leadership ability to drive decision-making within a multi-disciplinary, matrix teams
  • Ability to demonstrate effective leadership behaviors to ensure effective outcomes, including business agility as well as a curious, open-minded, and solution focused mindset
  • Effective project management skills
  • Independent management of workload and expectations
  • Scientifically independent
  • Enterprise and entrepreneurial mindset
  • Collaborate with key experts across the company including Clinical Development and Business Development (BD) to drive translational strategy from preclinical development through candidate selection and contribute to translational strategies in early clinical development through early Proof of Concept
  • Establish stage-appropriate project translational strategy for a differentiated asset to address unmet patient need with key “Go/No Go” decision points
  • Design non-clinical experiments to support biomarker strategy, combination strategy as well as overall MOA-related translational questions
  • Contribute to the analysis and interpretation of clinical biomarker results, evaluation of translational hypothesis based on clinical data, and data-driven generation of new hypotheses
  • Build and develop deep expertise in disease areas within ophthalmology, which are prioritized by the company. Identify possible mechanisms, disease models, preclinical POC approaches
  • Based on the scientific questions raised in the project, and in accordance with the translational and biomarker plan of the project, propose study designs and sequences (based on actual knowledge and literature review)
  • Generate clear, testable translational hypothesis to address unmet needs (mechanism of action, pharmacodynamics, patient selection)
  • Identify most relevant models, liaise with the best CRO and interact with academic experts to evaluate potential assets
  • In collaboration with clinical development, define translational strategy on projects with the objective to guide clinical development: indication identification, patient stratification strategy, combination potential, optimization of dose selection, overall biomarker strategy, etc
  • In partnership with clinical development, build the differentiation strategy for the therapeutic as well as defining the clinical and mechanism of action hypothesis and disease indication selection for early clinical development
  • Contribute to hypothesis-driven study design, execution, and data analysis, including identification of most relevant preclinical and ex vivo models
  • Identify key scientific questions in the projects and builds translation sciences plan according to their priority level
  • Bring scientific expertise to due diligence in collaboration with BD team, identify main risks and mitigation plan in their area of expertise
  • Build open relationships with peers and external partners to ensure best decision making
  • Clearly identify risks and mitigation plans. Ensures team contribution to clinical development plan

Tarsus Pharamceuticals

Tarsus Pharamceuticals


Tarsus Pharmaceuticals, Inc. focuses on developing innovative therapeutics for various eye conditions, including an FDA-approved treatment for Demodex blepharitis called XDEMVY™, utilizing advanced pharmaceutical formulations and scientific research to address high unmet medical needs in eye care. The main technologies used in their product include advanced pharmaceutical formulations and scientific research.

Company Stage


Total Funding



Irvine, California



Growth & Insights

6 month growth


1 year growth


2 year growth