As the Associate Director, Pharmacology, you will work alongside and supervise a small team (1-2 research associates) providing hands on oversight and day-to-day support of the execution of in-vivo pharmacodynamic disease area. This position requires an ability to define the therapeutic context into which specific programs are being developed and a demonstrated track record of successful innovative thinking and leadership in the advancement of new drug discovery programs.

Responsibilities

• Provide scientific leadership in the area of cardiac or skeletal muscle biology and function from program conception to candidate nomination for clinical development as well as ongoing translational studies for compounds once clinical studies begin
• Provide functional line management in pharmacology for respective programs, including design and execution of lead optimization paradigm, experimental planning, oversight in the development of new experimental protocols and procedures, and management and analysis of resulting experimental data
• Present experimental results at internal meetings and scientific conferences
• Propose and articulate the scientific and therapeutic hypotheses for new drug discovery programs
• Provide scientific leadership and management of both internal resources and external collaborations to characterize the action of small molecules on their targets and place the results into a therapeutic context.
• Management of budget and resources to conduct internal and CRO-based studies to drive projects forward

Qualifications

• A PhD with 8+ years of direct drug discovery experience
• Demonstrated record of achievement in bringing discovery programs from concept through to selection of IND candidate
• Significant hands-on prior experience with the execution of animal studies related to the evaluation of cardiac or skeletal muscle function, including contractility, metabolism, or growth in disease model
• Excellent leadership and mentorship skills with experience leading a successful team of research scientists and demonstrated ability to mentor junior PhDs and associates working in collaborative, multidisciplinary drug discovery programs
• Excellent communication skills and ability to work in multidisciplinary project teams