Full-Time
Director – Clinical Operations
Develops targeted cancer therapies using synthetic lethality
Senior, Expert
Cambridge, MA, USA
- BA/BS preferably in nursing, biology, biochemistry or related area (advanced degree desirable), with at least 10 years of experience in clinical research operations
- Minimum of 2 years of oncology experience required, 5 years preferred
- Biotechnology experience a plus
- Early phase experience, including IND submissions, required
- Strong vendor management and project management skills are critical
- Excellent written and oral communication skills
- Strong working knowledge of GCP/ICH and other applicable regulations/guidelines, required
- Good organizational/prioritization skills with strong attention to detail
- Working knowledge of oversight requirements and an eye for quality, required
- Strong proficiency with MS Office programs such as Outlook, Word, Excel, PowerPoint, and SharePoint, required
- Collaborative spirit for working positively and effectively with cross-functional teams and partners is essential
- Travel of up to 25% required
- You will oversee the development of clinical trial project timelines and ensure communication and understanding of risks and challenges; establish plans and monitor metrics; ensure that timelines are accurate and comprehensive
- Work cross-functionally to coordinate the relevant and timely exchange of information and materials to support clinical trial deliverables
- Manage clinical trials from start-up through close-out to ensure that both internal and external deliverables are on time and on budget while collaborating across functional areas
- Proactively manage clinical trial outsourced partners, including identification of risk, to ensure trial deliverables and performance goals are met
- Maintain partnerships (positive relationships) with CRO counterparts; proactively review and identify potential issues or problems with the sites and communicate/escalate to clinical leadership
- Collaborate with CROs to keep the clinical study database current, accurate, and routinely cleaned
- Manage the scope of work, change notifications, contract modification, site trial agreements, and other necessary budgetary information for clinical trial operations
- Support and manage oversight activities of all necessary vendors to ensure a high level of operational excellence is maintained
- Additional duties and responsibilities as required
Tango Therapeutics, a biotechnology firm, stands out due to its unique approach to cancer treatment, utilizing advances in DNA sequencing and CRISPR-based target discovery to develop novel medicines targeting cancer vulnerabilities. The company's focus on synthetic lethality, a method that targets specific genes in cancer cells leaving normal cells largely unaffected, offers a potential for enhanced anti-tumor efficacy and reduced toxicity. Furthermore, Tango's patient-centric approach and deep understanding of genetic subtypes of cancer enable it to identify novel drug targets and combinations, accelerating the development of transformational new therapies for patients with well-defined populations currently lacking effective treatment options.
Company Stage
IPO
Total Funding
$537M
Headquarters
Boston, Massachusetts
Founded
2017