Director – Clinical Operations
Posted on 8/2/2023
Tango Therapeutics

51-200 employees

Develops targeted cancer therapies using synthetic lethality
Company Overview
Tango Therapeutics, a biotechnology firm, stands out due to its unique approach to cancer treatment, utilizing advances in DNA sequencing and CRISPR-based target discovery to develop novel medicines targeting cancer vulnerabilities. The company's focus on synthetic lethality, a method that targets specific genes in cancer cells leaving normal cells largely unaffected, offers a potential for enhanced anti-tumor efficacy and reduced toxicity. Furthermore, Tango's patient-centric approach and deep understanding of genetic subtypes of cancer enable it to identify novel drug targets and combinations, accelerating the development of transformational new therapies for patients with well-defined populations currently lacking effective treatment options.
Data & Analytics

Company Stage


Total Funding





Boston, Massachusetts

Growth & Insights

6 month growth


1 year growth


2 year growth

Cambridge, MA, USA
Experience Level
Desired Skills
Google Cloud Platform
Operations & Logistics
  • BA/BS preferably in nursing, biology, biochemistry or related area (advanced degree desirable), with at least 10 years of experience in clinical research operations
  • Minimum of 2 years of oncology experience required, 5 years preferred
  • Biotechnology experience a plus
  • Early phase experience, including IND submissions, required
  • Strong vendor management and project management skills are critical
  • Excellent written and oral communication skills
  • Strong working knowledge of GCP/ICH and other applicable regulations/guidelines, required
  • Good organizational/prioritization skills with strong attention to detail
  • Working knowledge of oversight requirements and an eye for quality, required
  • Strong proficiency with MS Office programs such as Outlook, Word, Excel, PowerPoint, and SharePoint, required
  • Collaborative spirit for working positively and effectively with cross-functional teams and partners is essential
  • Travel of up to 25% required
  • You will oversee the development of clinical trial project timelines and ensure communication and understanding of risks and challenges; establish plans and monitor metrics; ensure that timelines are accurate and comprehensive
  • Work cross-functionally to coordinate the relevant and timely exchange of information and materials to support clinical trial deliverables
  • Manage clinical trials from start-up through close-out to ensure that both internal and external deliverables are on time and on budget while collaborating across functional areas
  • Proactively manage clinical trial outsourced partners, including identification of risk, to ensure trial deliverables and performance goals are met
  • Maintain partnerships (positive relationships) with CRO counterparts; proactively review and identify potential issues or problems with the sites and communicate/escalate to clinical leadership
  • Collaborate with CROs to keep the clinical study database current, accurate, and routinely cleaned
  • Manage the scope of work, change notifications, contract modification, site trial agreements, and other necessary budgetary information for clinical trial operations
  • Support and manage oversight activities of all necessary vendors to ensure a high level of operational excellence is maintained
  • Additional duties and responsibilities as required