Director – Clinical Scientist @ Verve Therapeutics

The Company

Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve’s gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. The company is advancing a pipeline of precision genetic medicines, led by VERVE-101, which is being developed initially for heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.

The Position

Verve is seeking an experienced Director, Clinical Scientist to join our team as we continue to advance gene editing medicines for cardiovascular disease into clinical development. In this position, you will be an integral part of the clinical development team supporting the execution of early phase clinical studies. You will report to the Vice President of Genomic Medicine. The ideal candidate will have outstanding communication skills, attention to detail, and the ability to thrive independently in a highly innovative and fast paced environment.

Job Responsibilities

Review, analyze, and interpret emerging clinical trial data (including biomarkers, clinical pharmacology, and safety data) and lead preparation for key study meetings (e.g. investigator meetings, monitoring committees, advisory boards)
Partners with the medical monitor on oversight of clinical trial activities, including safety reviews and site interactions
Liaise with the broader clinical development team at Verve (clinical operations, data management, and regulatory teams)
Contribute to authoring key study and regulatory documents (e.g. protocol, ICF, study manuals, briefing books)
Leads internal meetings to review topics and develop mitigation plans
Contribute to the development of presentations, abstracts, and publications emerging from clinical and translational studies
Collaborate with clinical and research teams to implement the clinical biomarker strategy for early phase clinical studies
Ensure compliance of all activities with ICH/GCP guidelines, applicable regulatory requirements, and Verve SOPs
Other duties as assigned

Qualifications

Advanced degree in life sciences (PhD, MD or both)
- PhD with 7+ years of clinical development experience in an industry setting
- MD with 1+ years of clinical development experience in an industry setting
- PhD and MD with 1+ years of clinical development experience in an industry setting
Experience with the development of key clinical study documents
Experience with the analysis and review of clinical data
Working knowledge of biostatistics, GCP, and regulatory requirements for clinical studies
Track record of working with and managing CROs and external vendors
Strong attention to detail and organizational skills
Exceptional verbal and written communication skills
Ability to build strong relationships and work effectively with cross-functional teams

EEO Statement

Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & Staffing Agencies

Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.

The Company

The Position

Job Responsibilities

Qualifications

EEO Statement

Recruitment & Staffing Agencies

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