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Full-Time

Staff Software Engineer

Confirmed live in the last 24 hours

Karius

Karius

51-200 employees

Non-invasive diagnostic tests for infections

AI & Machine Learning
Healthcare

Compensation Overview

$146.4k - $219.6kAnnually

Expert

San Carlos, CA, USA + 1 more

Category
Backend Engineering
Full-Stack Engineering
Software Engineering
Required Skills
Kubernetes
Microsoft Azure
JavaScript
Management
Git
Node.js
Data Structures & Algorithms
Nest.js
SQL
Apache Kafka
Docker
TypeScript
AWS
JIRA
REST APIs
Confluence
Development Operations (DevOps)
Google Cloud Platform
Requirements
  • BS in Computer Science, Software Engineering, or related technical fields involving algorithms and coding.
  • 10+ years of software engineering experience, including designing, developing, and maintaining backend solutions in a production environment.
  • A deep understanding of various system architectural patterns, such as event-driven microservices, and a strong hands-on experience with related technologies such as Kafka.
  • Expert-level experience with Typescript/javaScript backend stack using frameworks such as Express, Nest.js, and Node.js.
  • Practical examples of complex system data modeling and servicing using REST, GraphQL, no-SQL/SQL databases & ORMs.
  • Experience with DevOps culture using cloud computing in AWS (strongly preferred), Azure, or GCP.
  • A deep understanding of and hands-on experience with software deployment and operation using containerization technologies like Docker and container management like Kubernetes.
  • Experience with development lifecycle management tools like Jira, Confluence, GitHub or similar.
Responsibilities
  • Own the design and development of software services that drive the Karius genomics lab workflows and related business processes to generate life-saving diagnostic reports
  • Follow Domain Driven Design to clearly document the system architecture, service design, and the interfaces
  • Ensure the software services meet expected quality gates by developing unit and functional tests
  • Collaborate with cross-functional teams such as Lab Operations, Customer Success, Finance, Product Management, and Quality Engineering, and follow the defined Engineering SDLC to deliver value to the customers and users
  • Contribute to the engineering organization’s technical efforts such as design and code reviews, technology evaluations, and development of proof of concepts
  • Provide production operation support for diagnostics software services
  • Contribute to advancing a culture of a high-performing team by having close collaboration and engagement with the rest of the engineering team in solving challenges as they arise.

Karius focuses on medical diagnostics for infectious diseases, offering the Karius Test, a liquid biopsy that detects over 1,000 pathogens from a single blood sample. This non-invasive test is quick and helps clinicians treat hospitalized patients by reducing the need for multiple invasive tests that can delay treatment. The Karius Test utilizes advanced genomics and artificial intelligence to identify microbial cell-free DNA (mcfDNA) in the bloodstream, providing insights into the pathogens responsible for infections. Karius differentiates itself from competitors by offering a faster, non-invasive alternative to traditional diagnostic methods, which can save lives and lower healthcare costs. The company's goal is to enhance infectious disease diagnostics through continuous learning and improvement of their machine learning algorithms and genomic databases.

Company Stage

Series C

Total Funding

$345M

Headquarters

Redwood City, California

Founded

2014

Growth & Insights
Headcount

6 month growth

15%

1 year growth

13%

2 year growth

11%
Simplify Jobs

Simplify's Take

What believers are saying

  • Securing $100M in Series C funding from prominent investors like Khosla Ventures and 5AM Ventures positions Karius for significant expansion and technological advancement.
  • The Karius Test's ability to detect a wide range of pathogens quickly can lead to faster treatment decisions, potentially saving lives and reducing healthcare costs.
  • The addition of experienced board members, including those from Khosla Ventures and Gilde Healthcare, brings valuable expertise and strategic guidance to the company.

What critics are saying

  • The high cost of advanced genomic diagnostics may limit widespread adoption, particularly in resource-constrained healthcare settings.
  • The competitive landscape in medical diagnostics is intense, with numerous companies vying for market share, which could impact Karius's growth.

What makes Karius unique

  • Karius leverages advanced genomics and AI to detect over 1,000 pathogens from a single blood sample, offering a non-invasive and rapid diagnostic alternative unlike traditional methods.
  • The continuous updating of their reference genome databases ensures that Karius stays at the forefront of infectious disease diagnostics, providing real-time insights.
  • The FDA Breakthrough Device designation for the Karius Test underscores its innovative approach and potential impact on the diagnosis and management of infectious diseases in immunocompromised patients.