Full-Time

Staff Software Engineer

Posted on 8/8/2024

Karius

Karius

51-200 employees

Non-invasive diagnostic tests for infections

Biotechnology
Healthcare

Compensation Overview

$146.4k - $219.6kAnnually

Senior, Expert

San Carlos, CA, USA + 1 more

More locations: Remote in USA

Redwood City is hybrid; remote option available for the USA.

Category
Backend Engineering
Software Engineering
Required Skills
Kubernetes
Microsoft Azure
JavaScript
NoSQL
Git
Node.js
Nest.js
SQL
Apache Kafka
GraphQL
Docker
TypeScript
AWS
JIRA
Confluence
Development Operations (DevOps)
Google Cloud Platform
Requirements
  • Bachelor's degree in Computer Science or Software Engineering.
  • 10+ years of experience designing, developing, and maintaining backend solutions in a production environment.
  • 5+ years of hands-on experience with various system architectural patterns, such as event-driven microservice using Kafka.
  • 5+ years of hands-on experience with Typescript/javaScript backend stack using frameworks such as Express, Nest.js, and Node.js.
  • Practical examples of complex system data modeling and servicing using REST, GraphQL, no-SQL/SQL databases & ORMs.
  • Experience with DevOps culture using cloud computing in AWS (strongly preferred), Azure, or GCP.
  • A deep understanding of and hands-on experience with software deployment and operation using containerization technologies like Docker and container management like Kubernetes.
  • Experience with development lifecycle management tools like Jira, Confluence, GitHub or similar.
  • Experience in healthcare, life sciences, or other regulated industries.
Responsibilities
  • Design software services that drive the Karius genomics lab workflows and related business processes to generate life-saving diagnostic reports.
  • Follow Domain Driven Design to clearly document the system architecture, service design, and the interfaces.
  • Ensure the software services meet expected quality gates by developing unit and functional tests.
  • Collaborate with cross-functional teams such as Lab Operations, Customer Success, Finance, Product Management, and Quality Engineering, and follow the defined Engineering SDLC to deliver value to the customers and users.
  • Contribute to the engineering organization’s technical efforts such as design and code reviews, technology evaluations, and development of proof of concepts.
  • Provide production operation support for diagnostics software services.
  • Contribute to advancing a culture of a high-performing team by having close collaboration and engagement with the rest of the engineering team in solving challenges as they arise.
  • Research and introduce new technologies that will add value to Karius products.

Karius focuses on medical diagnostics for infectious diseases, offering the Karius Test, a liquid biopsy that detects over 1,000 pathogens from a single blood sample. This non-invasive test is quick and helps clinicians treat hospitalized patients by reducing the need for multiple invasive tests that can delay treatment. The Karius Test utilizes advanced genomics and artificial intelligence to identify microbial cell-free DNA (mcfDNA) in the bloodstream, providing insights into the pathogens responsible for infections. Karius sells these diagnostic tests to healthcare providers, aiming to save lives and lower healthcare costs by offering a faster alternative to traditional methods. Their proprietary machine learning algorithms analyze genomic data in real time, with continuously updated reference genome databases, ensuring they remain competitive in infectious disease diagnostics.

Company Stage

Series C

Total Funding

$311.3M

Headquarters

Redwood City, California

Founded

2014

Growth & Insights
Headcount

6 month growth

0%

1 year growth

0%

2 year growth

-2%
Simplify Jobs

Simplify's Take

What believers are saying

  • Karius secured $100M to expand its test beyond 400 U.S. hospitals.
  • FDA Breakthrough Device Designation boosts credibility and market potential.
  • Growing demand for non-invasive diagnostics aligns with Karius's offerings.

What critics are saying

  • Competition from AlphaFold 3 could overlap with Karius's genomic insights.
  • Rapid AI advancements by competitors may outpace Karius's technology.
  • Reliance on continuous funding rounds indicates potential financial instability.

What makes Karius unique

  • Karius Test detects over 1,000 pathogens from a single blood sample.
  • The test uses advanced genomics and AI for rapid, non-invasive diagnostics.
  • Karius's proprietary algorithms analyze genomic data in real time.

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Benefits

Remote Work Options

Hybrid Work Options

INACTIVE