Full-Time

Manager - Patient Advocacy & Engagement

Posted on 11/12/2025

Orca Bio

Orca Bio

201-500 employees

Develops and commercializes safer cell therapies

No salary listed

Chicago, IL, USA

Remote

Preferred remote location: Chicago or midwestern US.

Category
Biology & Biotech (2)
,
Requirements
  • Bachelor’s degree in life sciences, public health, social work, policy, or a related field (advanced degree preferred)
  • Minimum 5 years of professional experience in patient advocacy, medical affairs, public health, or coalition building, with preference for oncology, hematology, or cell therapy experience
  • Strong understanding of the biotech/pharma industry, including the drug development process and regulatory frameworks
  • Demonstrated ability to collaborate across functions and influence at all levels of an organization
  • Track record of building consensus and fostering buy-in among diverse stakeholders
  • Exceptional interpersonal skills and cultural awareness to navigate a wide range of professional and community interactions
Responsibilities
  • Build and maintain trusted relationships with patient leaders, advocacy organizations, caregivers, professional societies and other stakeholders in the blood cancer community through thoughtful and compliant engagement
  • Design and deliver community-focused initiatives, including advocacy roundtables, insight-gathering sessions, landscape assessments and workshops
  • Assist in managing patient advocacy grants, sponsorships and related requests in alignment with company policies
  • Coordinate with internal teams to bring patient perspectives into clinical trial activities, medical education and external engagement
  • Represent Orca Bio at advocacy events, reinforcing the company’s commitment to patient-focused innovation
  • Collaborate with Corporate Communications, Medical Affairs and Commercial teams to ensure consistent external messaging
  • Translate community insights into actionable recommendations that inform cross-functional strategies.
  • Champion a patient-first culture by elevating patient stories, perspectives and unmet needs across the company
  • Support patient-centric initiatives such as awareness campaigns, educational events, and development of accessible lay summaries of scientific content
Desired Qualifications
  • Embodies a patient-centric mindset with a commitment to elevating patient and caregiver perspectives in all aspects of work
  • Ability to create and sustain trusted partnerships with diverse stakeholders
  • Skilled in developing and executing advocacy initiatives and community programs
  • Strong written and verbal skills, including translating complex science into accessible language
  • Understanding of oncology/hematology advocacy ecosystems and stakeholder dynamics
  • Knowledge of regulatory compliance standards related to patient engagement and communications
  • Experience managing budgets, grants, sponsorships and vendors in a compliant manner

Orca Bio develops and commercializes cell therapies to improve outcomes for patients. It works by researching, developing, and producing therapies that use the body’s own cells to treat diseases, with products sold to healthcare providers who administer them to patients. The company aims to enhance the safety and effectiveness of cell therapies, making treatments more reliable for conditions that lack good options. Orca Bio differentiates itself through its focus on delivering safer, more effective therapies and by fostering a strong team culture with active stakeholder communication, including a regularly updated newsroom. Overall, its goal is to expand access to improved cell therapies and become a leading player in the cell therapy market.

Company Size

201-500

Company Stage

Debt Financing

Total Funding

$542M

Headquarters

Menlo Park, California

Founded

2016

Simplify Jobs

Simplify's Take

What believers are saying

  • Orca-T’s April 6, 2026 PDUFA creates an immediate commercialization catalyst.
  • $250 million financing plus $100 million liquidity funds launch readiness and expansion.
  • Bijan Nejadnik and Steve Gavel strengthen regulatory and commercial execution.

What critics are saying

  • FDA delay or rejection of Orca-T destroys the near-term launch opportunity.
  • East Coast manufacturing expansion risks validation failures, contamination, and supply disruptions.
  • Payer resistance blocks transplant-level pricing without durable long-term outcomes data.

What makes Orca Bio unique

  • Orca Bio uses single-cell precision to build proprietary allogeneic cell therapies.
  • Orca-T combines regulatory T-cells, stem cells, and conventional T-cells from donors.
  • Its 100,000-square-foot facility enables 72-hour vein-to-vein manufacturing turnaround.

Help us improve and share your feedback! Did you find this helpful?

Your Connections

People at Orca Bio who can refer or advise you

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Unlimited Paid Time Off

401(k) Retirement Plan

Parental Leave

Growth & Insights and Company News

Headcount

6 month growth

-3%

1 year growth

-1%

2 year growth

-1%
The Pharma Letter
Apr 2nd, 2026
FDA review not plain sailing for Orca.

FDA review not plain sailing for Orca. 2 April 2026 Privately-held US cell therapy company Orca Bio announced that the US Food and Drug Administration (FDA) has extended the review timeline of its Biologics License Application (BLA) for Orca-T for the treatment of patients with hematologic malignancies. This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here. Try before you buy Free. 7 day trial access * All the news that moves the needle in pharma and biotech * Exclusive features, podcasts, interviews, data analyses and commentary from its global network of life sciences reporters. * Receive The Pharma Letter daily news bulletin, free forever. Become a subscriber £820. Or £77 per month * Unfettered access to industry-leading news, commentary and analysis in pharma and biotech. * Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results. * Daily roundup of key events in pharma and biotech. * Monthly in-depth briefings on Boardroom appointments and M&A news. * Choose from a cost-effective annual package or a flexible monthly subscription The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It's part of the key information for keeping me informed Chairman, Sanofi Aventis UK More on this story... 23 March 2026 25 March 2026 1 April 2026 Companies featured in this story. Sign up to receive email updates Join industry leaders for a daily roundup of biotech & pharma news Today's issue. 2 April 2026 Company spotlight. A clinical-stage biotechnology company developing atacicept and other targeted therapies for serious immunological and kidney diseases with high unmet medical need. More features in biotechnology. 2 April 2026

Business Wire
Jan 12th, 2026
Orca Bio Announces $250M in Aggregate Financing in Preparation for Potential Commercialization

Orca Bio announces $250M in aggregate financing to support launch readiness leading up to the Orca-T® PDUFA date of April 6, 2026.

Silicon Valley Daily
Jan 10th, 2026
Orca Bio Secures $250 Million in Financing

Orca Bio secures $250 million in financing. MENLO PARK - Orca Bio, a late-stage biotechnology company committed to transforming the lives of patients through high-precision cell therapy, has completed a Series F financing round led by Lightspeed Venture Partners. With $250 million in new equity capital from its two most recent financing rounds, along with a 2025 amendment to its Silicon Valley Bank credit facility providing up to $100 million in additional liquidity, Orca Bio possesses the financial strength to scale its commercial operations and advance its clinical pipeline. The proceeds will be used to ensure commercial readiness as the company approaches the April 6, 2026 Prescription Drug User Fee Act (PDUFA) target action date for Orca-T, Orca Bio's lead investigational allogeneic T-cell immunotherapy. The funding will help strengthen the company's infrastructure to support future commercial scale, including the addition of East Coast manufacturing capacity to complement its Sacramento, CA operations. The capital will also support the accelerated advancement of Orca Bio's pipeline across multiple clinical programs designed to expand treatment to more patients in need.

FiercePharma
Jan 9th, 2026
Orca Bio secures $250M to prepare blood cancer cell therapy for commercial launch

Orca Bio has raised $250 million across two funding rounds to prepare for the commercialisation of its blood cancer cell therapy Orca-T. The California-based biotech also secured up to $100 million in credit from Silicon Valley Bank. Orca filed for FDA approval of Orca-T last year, with a decision expected by 6 April. The allogeneic T-cell immunotherapy uses purified donor regulatory T cells to prevent graft-versus-host disease with less immunosuppression than conventional transplantation methods. A phase 3 trial showed significantly better survival outcomes compared to standard tacrolimus and methotrexate treatment. The funding will support manufacturing expansion, including new East Coast capacity. Mike Hirschmann, formerly of Legend Biotech, now leads commercial operations following leadership changes last year.

Orca Bio
Jan 9th, 2026
Orca Bio Announces $250M in Aggregate Financing in Preparation for Potential Commercialization - Orca Bio

Our CompanyAbout UsLeadershipOur ApproachHigh-Precision TechnologyManufacturingOur PipelineOrca-TOrca-QScientific PublicationsExpanded Access PolicyPatients & FamiliesOur PurposeKey TermsMore ResourcesCulture & CareersWho We AreOpen PositionsNewsroomOur CompanyAbout UsLeadershipOur ApproachHigh-Precision TechnologyManufacturingOur PipelineOrca-TOrca-QScientific PublicationsExpanded Access PolicyPatients & FamiliesOur PurposeKey TermsMore ResourcesCulture & CareersWho We AreOpen PositionsNewsroom HomeWho We AreWhat We DoOur Clinical ProgramsExpanded AccessJoin Our TeamNewsroomContact UsPrivacy PolicyTerms of UsePress releaseMenlo Park, CAJanuary 9, […]

INACTIVE