WHO WE ARE
Arsenal Biosciences Inc. is a clinical stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We are seeking a talented and experiencedAssociate Director, Cell Line Development to work onsite based in our South San Francisco office.
ArsenalBio’s mission and purpose is very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines with the goal to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.
Driven by a collective of diverse experts across multi-scientific disciplines as well as clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.
This means you’ll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most.
We are seeking a highly motivated individual to lead cell line development at ArsenalBio. Reporting to the Vice President of Preclinical Pharmacology, this role requires substantial expertise in cell line engineering and development. Deep knowledge and extensive experiences in oncology target biology and drug discovery is also highly desirable. The successful individual will not only oversee and lead the cell line development group but work closely with project teams throughout Discovery and Preclinical Development to design and generate engineered cell lines in support of preclinical programs.
WHAT YOU’LL DO
- Lead a group of scientists that provides centralized support for cell line generation
- Lead the development, application and optimization of new technologies for modifying the genomes of mammalian cells
- Employ strategies for the genetic modification of cell lines
- Lead activities in generating and maintaining master and working cell bank inventories across a portfolio of engineered cell lines
- Lead analysis and QC processes on cell lines at the DNA and protein level
- Provide expert support for cell line engineering experiment design and assay development to the broader scientific team.
- Coordinate tasks across multiple projects, demonstrating prioritization and planning.
- Interpret and effectively execute experiments in line with project timelines and goals
- Maintain familiarity with current literature related to the scope of ArsenalBio’s research focus
- Mentor scientists within the group in areas of technical expertise
WHO YOU ARE
- PhD in Cell or Molecular Biology, Biological Sciences or a related field, with 5+ years of relevant research experience in industry or academia
- Expertise with CRISPR gene editing and lentiviral transduction workflows, cell engineering and cell culture
- Experience developing/optimizing gene editing protocols
- Experience analyzing mammalian cells by flow cytometry for target surface expression
- Experience with Fluorescence-activated cell sorting (FACS)
- Entrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done
- Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results
- Flexible mindset with ability to think outside the box, creative approach to problem solving, and comfort in working with ambiguous data in an open-ended, exploratory process
- Demonstrated ability to perform as a team player, with strong organizational skills, record keeping and interpersonal communication skills (verbal and written)
BENEFITS AND PAY
ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge.
Our people-first culture fosters a deep appreciation for humanity, both in the people we endeavor to serve as well as each other. We are proud to work for a company that is driven by diversity in experiences, ideas and interests, and one that empowers us in an environment that embraces both unity and inclusivity.
We have robust tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as our people are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.
We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
The estimated base salary offer for the preferred primary location of the San Francisco Bay area ranges from $169,000- $207,000. Salary ranges for other locations may vary from this range. Base pay offered may vary depending on job related knowledge, experience, education, and location. In addition to these factors, we believe in the importance of pay equity and consider internal equity of our current employees as part of any final offer.
To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.
