Scientist – Upstream Development
Confirmed live in the last 24 hours
Shape Therapeutics

51-200 employees

Pioneering programmable RNA medicines using AI
Company Overview
Shape Therapeutics Inc. (ShapeTX) is a pioneer in the field of programmable RNA medicines, leveraging a robust AI-driven platform to analyze vast datasets and design effective treatments for a wide range of diseases, from rare genetic disorders to debilitating conditions like Alzheimer's and Parkinson's. The company's unique approach utilizes ADAR, a naturally occurring enzyme, to correct protein-making instructions by recoding RNA, offering a potential solution to numerous genetic disorders without permanently altering DNA. Additionally, ShapeTX's TruStable™ stable cell lines significantly enhance the manufacturability of RNA medicines at any scale, ensuring accessibility for patients.
AI & Machine Learning
Data & Analytics

Company Stage

Series B

Total Funding





Seattle, Washington

Growth & Insights

6 month growth


1 year growth


2 year growth

Seattle, WA, USA
Experience Level
Biology & Biotech
  • Experience with aseptic technique and small-scale mammalian cell culture
  • Experience with bioreactor operations
  • Experience generating and analyzing large datasets to understand impact of process parameters on product yield and quality
  • Experience with statistical software like JMP
  • Prior experience in cell culture process optimization in an industry or academic setting is highly desirable
  • Experience working with viral vectors is desirable
  • Experience with electronic lab notebooks
  • Ability to troubleshoot and think analytically
  • Strong work ethic and a team player
  • Ability to effectively communicate via email, interpersonally, and in presentation
  • Cell culture media optimization to improve viral vector yield and product quality
  • Cell line and upstream process improvement and intensification
  • Optimize small scale and bioreactor runs for optimum vector production
  • Work with external partners on technology development projects
  • Document technical results and best practices in ELNs, SOPs, summary reports, etc
  • Efficiently organize time and resources to meet deadlines
  • Maintain a detailed electronic laboratory notebook
Desired Qualifications
  • Bachelor of Science degree in Cellular Biology, Engineering, Biochemistry, Biology, or a related discipline with 5+ years of post-degree experience in an academic or industry research capacity or Masters with 2-3 years of post-degree experience
  • Ph.D. in Cellular Biology, Engineering, Biochemistry, Biology, or a related discipline with 0-2 years post-degree experience