Senior Research Associate II
Next Generation Sequencing, 23034-B-690-NGS
Posted on 4/25/2023
INACTIVE
ArsenalBio

201-500 employees

Programmable cell therapy company
Company Overview
ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer. ArsenalBio is creating products are being designed to herald the transition of adoptive cell therapy from a hospital based treatment to outpatient therapy, like most other cancer treatments.
AI & Machine Learning
Data & Analytics
B2B

Company Stage

Series B

Total Funding

$525.8M

Founded

2019

Headquarters

South San Francisco, California

Growth & Insights
Headcount

6 month growth

0%

1 year growth

6%

2 year growth

48%
Locations
San Bruno, CA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
CategoriesNew
Lab & Research
Biology & Biotech
Requirements
  • Masters with 2 + years of relevant experience; or Bachelor with 4 + years of relevant experience
  • 3+ years of full-time, hands-on NGS experience in an academic or industrial setting
  • Deep understanding of NGS library preparation and the principles of sequencing technologies
  • Previous work with a variety of NGS sample preparation workflows and analysis
  • Experience in high-content screening, single-cell genomics, or functional genomics
  • Significant experience in troubleshooting, method development, and optimization of molecular biology-based assays
  • Strong background in molecular biology and analytical techniques, including PCR/qPCR, ddPCR, molecular cloning, gene editing, enzymatic assays, and nucleic acid isolation and manipulation
  • Experience operating liquid handling robots or other lab automation for high-throughput assays desired
  • Experience in computational analysis of next-generation sequencing data
  • Ability to quickly learn new skills and knowledge on the job, demonstrate productivity and deliver high-quality results
Responsibilities
  • Deploy high- and low-throughput NGS library preparation strategies for bulk, single-cell, and multi-omic applications
  • Create NGS libraries from single cells, tissues, and isolated DNA/RNA to further ArsenalBio research and discovery
  • Establish novel NGS methods to extract new types of information from research and clinical samples
  • Help oversee the operation and maintenance of numerous Illumina instruments
  • Participate in the overall management of NGS operations
  • Assist in troubleshooting problematic library preps and sequencing issues
  • Contribute to ongoing improvements in storing, tracking, and analyzing NGS data
  • Evaluate new NGS technologies and platforms (e.g., spatial transcriptomics)
  • Identify promising new concepts in scientific publications and lead pilot studies of related experiments
  • Participate in cross-functional collaborations with multiple groups to advance broad company goals and objectives and assist in the design of genomics projects
  • Contribute NGS expertise, leadership, and technical guidance to cross-disciplinary teams
  • Advance NGS technology utilization and understanding across the company
  • Work closely with computational biologists to interpret NGS data