Senior Associate Scientist

We are seeking a dedicated, self-motivated Senior Associate Scientist to join our technology development and drug discovery efforts in the areas of immune tolerance, cell-based immune therapies and hematopoietic stem cell transplant biology. VelocImmune (VI) Next is an innovative technology development group that creates and uses complex mouse models and functional assays to study antibody, oligonucleotide, and cell-based therapies across various therapeutic areas in R&D. We hope you are excited by the opportunity to contribute to the development of industry-leading technologies and medicines for the treatment of cancers, genetic and autoimmune diseases.

As a Senior Associate Scientist in VI-Next, a typical day might include:

• Supporting mouse in vivo studies, including performing injections (IV, IP, SQ), routinely bleeding mice, harvesting tissues and isolating cells for downstream functional assays

• Performing multicolor (>12 color) flow cytometry and analyze flow cytometry data

• Performing and analyzing immunoassays such as ELISA and MSD

• Conducting cell co-culture experiments such as cytotoxicity assays and mixed lymphocyte reaction (MLR)

• Constructing DNA vectors and viral vectors for in vitro and in vivo studies

• Culturing and engineering primary cells and cell lines using transfection and viral transduction

• Maintaining an organized lab notebook, analyzing (FlowJo, Excel, GraphPad Prism, etc.) and presenting data at various internal meetings

This role might be for you if you:

• Enjoy working independently and collaboratively with other members of the group to advance testing of candidate therapeutics in mouse models of transplantation, tumors, and autoimmunity

• Have strong written and verbal communication skills, and enjoy problem-solving

• You are organized, flexible, able to coordinate multiple tasks independently, and enthusiastic to learn new skills

In order to be considered for this role, you must have a MS/BS in immunology, cell biology, molecular biology, or related fields with 3+ years of relevant experimental techniques. Must have a strong knowledge base of immunology. Experience in mouse handling, multi-color flow cytometry, and immunological methods is required. Experience in the research of targeted therapeutics including antibodies and cell therapies and/or in development of complex mouse models of tumors and transplantation is highly preferred. Ability to design experiments, analyze, and troubleshoot independently is highly desirable.