What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases. We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before. Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.

Key Responsibilities & Accountabilities:

• Develop, optimize, and implement biophysical assays to support process development & process characterization to drive late-stage activities towards BLA.
• Design and execute forced degradation, stability, impurity identification and characterization studies.
• Lead the technical transfer of assays to Quality Control or central testing laboratories and provide SME support as needed.
• Compile and present data and assist in authoring and reviewing of test methods, technical reports, and protocols.
• Cross-train personnel on various biophysical assays, as required, and provide guidance to junior research associates.
• Document all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner.

Knowledge, Skills & Capabilities:

• In depth knowledge of assay development for biologics including separation sciences (HPLC/UPLC), isoelectric focusing (icIEF), capillary electrophoresis (CE-SDS) and light scattering methods (MALS/DLS).
• Demonstrated experience with independent method development and complex study design.
• Experience with mass spectrometry (ESI-MS, intact and peptide map) is preferred but not required.
• Experience with technical transfer of GMP test methods for biologics.
• Innovative & collaborative with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals.
• Strong interpersonal, verbal, and written communication skills and knowledge of CRISPR gene editing technology.

Education & Relevant Work Experience:

• PhD in a life science discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering with 2+ years of relevant analytical development experience. Bachelors in a life science discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering with 12+ years of relevant analytical development and tech transfer experience or a Masters with 4+ years of experience.

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.