INACTIVE
Full-Time
Scientist II
Clinical stage genome editing for disease treatment
Biotechnology
Senior, Expert
Cambridge, MA, USA
Requirements
- In depth knowledge of assay development for biologics including separation sciences (HPLC/UPLC), isoelectric focusing (icIEF), capillary electrophoresis (CE-SDS) and light scattering methods (MALS/DLS)
- Demonstrated experience with independent method development and complex study design
- Experience with mass spectrometry (ESI-MS, intact and peptide map) is preferred but not required
- Experience with technical transfer of GMP test methods for biologics
- Innovative & collaborative with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals
- Strong interpersonal, verbal, and written communication skills and knowledge of CRISPR gene editing technology
- PhD in a life science discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering with 2+ years of relevant analytical development experience. Bachelors in a life science discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering with 12+ years of relevant analytical development and tech transfer experience or a Masters with 4+ years of experience
Responsibilities
- Develop, optimize, and implement biophysical assays to support process development & process characterization to drive late-stage activities towards BLA
- Design and execute forced degradation, stability, impurity identification and characterization studies
- Lead the technical transfer of assays to Quality Control or central testing laboratories and provide SME support as needed
- Compile and present data and assist in authoring and reviewing of test methods, technical reports, and protocols
- Cross-train personnel on various biophysical assays, as required, and provide guidance to junior research associates
- Document all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner
Company Stage
N/A
Total Funding
$884.6M
Headquarters
Cambridge, Massachusetts
Founded
2013
Growth & Insights
Headcount
6 month growth
↑ 11%1 year growth
↑ 19%2 year growth
↑ 11%INACTIVE