Senior Medical Director

About Kymera Therapeutics
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years.

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll contribute:

• Design and implement comprehensive global clinical development plans as the Clinical Lead on cross-functional teams, ensuring integration of scientific rigor and innovation.
• Develop and execute innovative strategies to expedite development cycles, focusing on efficient design and execution of Phase 2 and Phase 3 programs.
• Act as a clinical leader, engaging with academic advisors, principal investigators, patient groups, regulatory authorities, and industry collaborators.
• Utilize specialized knowledge in immunology and respiratory fields to support and enhance the clinical portfolio.
• Collaborate with regulatory leaders to develop and execute submission strategies, overseeing the creation and quality of clinical content for protocols, INDs, and regulatory reports, and ensuring the highest standards for all clinical documents and regulatory responses.
• Provide strategic input on next-generation targets in collaboration with discovery teams and lead the planning of Phase 1 clinical testing.
• Serve as Medical Monitor and sponsor representative with CROs, PIs, core laboratories and other organizations involved in clinical trials.
• Ensure timely execution of assets and studies within the immunology and respiratory portfolio.
• Develop and implement publication strategies, and actively contribute to key presentations.

Skills and experience you’ll bring:

• Advanced degree in medicine (e.g., M.D. or D.O. or equivalent). Clinical training in Pulmonary & Critical Care Medicine (board certified or eligible) is preferred.
• Minimum of 6 years of industry experience, with a focus on late clinical development; strong academic backgrounds with less experience may also be considered.
• Experience in inflammatory and immunological therapeutic areas is required; respiratory experience is advantageous.
• Proven expertise in leading late-stage clinical trials, including protocol design, study start-up, team management, data analysis, and medical monitoring.
• Experience with Investigational New Drug (IND) applications; experience with New Drug Applications (NDA) is a plus.
• Demonstrated capability as a clinical development representative on cross-functional drug development teams.
• In-depth knowledge of regulatory filings and interactions with health authorities.
• Thorough understanding of all phases of drug development.
• Exceptional communication skills with the ability to effectively present and engage a wide range of stakeholders.

Skills and experience not an exact match?:

Go ahead and submit your resume (and a cover letter, if you’d like!).  If this role isn’t right for you, we can keep you in mind for future opportunities.

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.