Job Description
The Non-Clinical Drug Safety (NDS) organization within our company’s Research Laboratories is currently seeking a senior scientist with immunotoxicology an background to join our Investigative Toxicology team at the West Point, PA site.
The senior scientist will be responsible for key aspects of immunotoxicology research and development, which includes but is not limited to understanding mechanisms of toxicity, supporting lead optimization, and developing novel assays and platforms for novel drug modalities. Further, the successful candidate is also expected to serve as a potential program toxicologist.
Key responsibilities include:
Lead the design and implementation of fit-for-purpose in vitro and in vivo investigative tox plans to support immunotoxicity risk assessment and mechanistic investigations of new drug candidates.
Responsible for the generation and reporting of immunophenotyping, antibody responses, and various immune or hematopoietic- cellular-based functional assessments. Accurately record data from experiments, including observations, measurements, and sample details, in electronic laboratory notebooks
Troubleshoot technical issues, provide data interpretation, and prepare high quality immunotoxicity assay/study reports.
Communicate effectively to Investigative Tox managers and stakeholders. Proactively identify gaps/risks in assay/study plans and inform the potential impact to team members.
Provide scientific leadership and immunotoxicology subject matter expertise at multidisciplinary team meetings.
Participate in external immunotoxicology consortia and symposia. Stay updated on the latest scientific research, regulatory guideline, and industry trends to guide informed decision and drive innovation in immunotoxicology safety assessment.
Qualification
PhD in life science, such as Toxicology, Immunology, Biology, Biochemistry, Chemistry, or a related discipline AND 0-3+ years of postdoctoral or industry experience in immunotoxicology or immunology areas OR MS AND 4+ years of experience
Hand-on experiences in immunoassays which can include flow cytometry, ELISPOT, TDAR, or other immune cell function/activity assessments (blastogenesis assay, NK cell function, cytokine release, etc.).
Strong communication skills, with the ability to interact effectively with colleagues across multiple teams.
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
Yes
Travel Requirements:
No Travel Required
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
OEB4, OEB5
Job Posting End Date:
01/12/2025
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