Full-Time

Senior Manager

IT Lab Systems

Confirmed live in the last 24 hours

Verve Therapeutics

Verve Therapeutics

201-500 employees

Develops gene editing therapies for cardiovascular disease

Biotechnology
Healthcare

Senior

Boston, MA, USA

Category
Lab & Research
Life Sciences
Required Skills
Data Science
AWS
Requirements
  • Bachelor’s degree in computer sciences or engineering field with at least 7 years related experience in the biotech or pharmaceutical industry preferred.
  • CompTIA Network+ or similar certification
  • CompTIA Security+ or similar certification
  • Strong communication skills, capable of effectively interfacing with both business stakeholders and technical teams.
  • Proven ability to collaborate and engage with individuals across all organizational levels.
  • Experience with AWS Storage Gateway and other cloud-based storage solutions.
  • Deep understanding of 21 CFR Part 11, software validation, and GxP compliance, particularly in QC and manufacturing environments.
  • Experience handling Big Data, especially in genomic sequencing.
  • Skilled in training and mentoring support staff on lab systems and processes.
  • Proficient in troubleshooting and maintaining equipment such as HPLCs, Mass Spectrometers, and Illumina Sequencers.
Responsibilities
  • Work closely with Research and Development (R&D), Manufacturing, and the Lab Operations team to translate business needs into technical solutions. Gaining alignment while communicating plans, changes, and improvements across functions.
  • Lead IT projects from concept to implementation, including timelines, resources, and budgets, ensuring alignment with business objectives.
  • Collaborate with Lab Operations to manage the instrument lifecycle (procurement, implementation, maintenance, and decommissioning).
  • Ensure all R&D IT solutions comply with GxP regulatory requirements and internal policies.
  • Ensure all systems are documented and staff trained, to facilitate operational support between the service desk and system users.
  • Streamline and enhance data management practices within the lab to improve data flow, accuracy, and compliance.
  • Maintain compliance with backup policies and data retention requirements, ensuring data recoverability and resiliency.
  • Provide technical support for Next Generation Sequencing (NGS) instruments, ensuring seamless integration with lab IT systems and processes.
  • Handle lab-based IT escalations, providing technical support and troubleshooting.
  • Manage, maintain, and troubleshoot key lab systems, including Empower, OpenLab, Waters Connect, and Unicorn.
  • Leverages technical expertise to provides mentorship to junior team members.
  • Other duties as assigned.

Verve Therapeutics focuses on developing gene editing treatments for cardiovascular disease. Their approach involves creating single-course therapies that aim to provide lasting solutions rather than ongoing treatments. The company specifically targets the PCSK9 and ANGPTL3 genes, which are known to help lower blood lipid levels. This focus on gene editing sets Verve apart from traditional therapies that require continuous management. The goal of Verve Therapeutics is to offer potentially curative options for patients with cardiovascular conditions, improving their long-term health outcomes.

Company Stage

IPO

Total Funding

$419.3M

Headquarters

Cambridge, Massachusetts

Founded

2018

Growth & Insights
Headcount

6 month growth

6%

1 year growth

8%

2 year growth

34%
Simplify Jobs

Simplify's Take

What believers are saying

  • Significant financial backing, including a $63 million Series A2 financing and $60 million from Eli Lilly, positions Verve for robust R&D and clinical trial activities.
  • The potential for a 'one-and-done' treatment for cardiovascular diseases could revolutionize the field and offer a high-impact, life-saving solution.
  • Early-stage success and strategic partnerships could lead to lucrative licensing deals and further investment opportunities.

What critics are saying

  • The clinical-stage nature of Verve's therapies means they are still years away from potential market approval, posing a long-term risk.
  • The recent stock price drop following a public offering indicates market volatility and potential investor uncertainty.

What makes Verve Therapeutics unique

  • Verve Therapeutics focuses on gene-editing therapies specifically for cardiovascular diseases, setting it apart from other CRISPR-based companies that target a broader range of conditions.
  • Their 'one-and-done' gene-editing approach aims to provide a single, curative treatment, which is a significant advantage over traditional, ongoing therapies.
  • Partnerships with major pharmaceutical companies like Eli Lilly enhance their credibility and provide substantial financial and research support.

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