Senior Software Engineer

Who we are

At Domino, we build software that helps the largest, AI-driven organizations build and operate advanced data science and AI solutions at scale. Our platform integrates a streamlined model development environment, MLOps capabilities, and novel features for collaboration, reuse, and reproducibility — all of which make data science teams more productive, reduce time to value, and ensure compliance. Our customers — like Johnson & Johnson, GSK, Bristol Myers, UBS, FINRA and the US Navy — are using our software to solve some of the most important challenges in the world, such as developing new medicines, securing our financial markets, or protecting our country. Backed by Sequoia Capital, Coatue Management, NVIDIA, Snowflake and other leading investors, we have been in business for a decade but are still a small team operating with the spirit of a startup. Especially in the world of AI today, we believe that the future is still being invented — and we want to be the ones building it. For more information, visit www.domino.ai

What we are building

The Life Sciences Team is revolutionizing the discovery and delivery of transformative therapies by empowering researchers, operators, and regulators with innovative tools and solutions. Our mission is to:

• Leverage industry-leading assets—data, metadata, and code—to deliver AI-driven efficiencies across the development lifecycle
• Integrate seamlessly with niche tools and frameworks while embedding role-based insights into user workflows
• Set the Gold Standard for collaboration among Sponsors, Academic Institutions, and Regulatory Bodies, ensuring the highest standards of reproducibility, auditability, and knowledge sharing

By fostering collaboration and enabling faster, safer therapy development, we’re setting a new benchmark for excellence in Life Sciences.

What your impact will be

In your first year, you will 

• Enhance Domino Datasets functionality to allow access via APIs, complementing traditional file system mounts
• Improve Git repository and version control support within Domino Projects and Workspaces
• Design and implement regulatory compliance features aligned with FDA requirements, ensuring the authenticity, confidentiality, and validation of electronic records
• Build end-to-end audit logging to provide comprehensive workflow transparency
• Automate external data version tracking to improve lineage and reproducibility for third-party data sources
• Optimize workspace performance, focusing on Kubernetes-based compute-on-demand IDE functionality

What we look for in this role

• 5+ years previously in a software engineering individual contributor role
• Building Scalable Systems: Developing and managing high-performance back-end systems in distributed compute environments
• Cross-Functional Collaboration: Integrating back-end systems with front-end interfaces and third-party services
• API Development: Designing secure, efficient APIs using technologies like RESTful APIs and gRPC
• Performance Optimization: Profiling and fine-tuning back-end systems, particularly in cloud environments and with container technologies like Docker and Kubernetes
• Testing and CI/CD: Implementing robust testing frameworks (unit, integration, end-to-end) and maintaining CI/CD pipelines
• Distributed Computing: Familiarity with frameworks like Apache Hadoop, Spark, Ray, or similar technologies
• Back-End Programming: Proficiency in languages like Python, Java, Scala, or Go to build scalable web services
• Architectural Design: Experience with service-oriented architectures (SOA) and modular, maintainable system design
• AI/ML Concepts: Knowledge of machine learning workflows and infrastructure is a plus

What we value

• We value a growth mindset. High-performing creative individuals who dig into problems and see the opportunities for success
• We believe in individuals who seek truth and speak the truth and can be their whole selves at work
• We value all of you that believe improving is always possible At Domino Everything is a work in progress – we can do better at everything
• We emphasize an environment of teaching and learning to equip employees with the tools needed to be successful in their function and the company
• We strongly believe in the value of growing a diverse team and encourage people of all backgrounds, genders, ethnicities, abilities, and sexual orientations to apply

#LI-Remote