Full-Time

Senior Manager

Market Access & Corporate Affairs

Posted on 9/11/2025

Blueprint Medicines

Blueprint Medicines

501-1,000 employees

Biopharma developing kinase inhibitors for cancer

No salary listed

Munich, Germany

Hybrid

Category
Business & Strategy (3)
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Requirements
  • Academic education and experience from similar positions (life science, economics, media)
  • Minimum of 5+ years’ experience in pharmaceutical/biotechnology field
  • Strong knowledge of Market Access and HTA/Payer requirements, standards and processes, including experience with national and regional authorities, including sick funds and other payers
  • Experience with communications and PR initiatives
  • Experience to manage complex projects and colaborate with multi-disciplinary teams
  • Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism
Responsibilities
  • Support with HTA (AMNOG) assessment procedure including written statement and oral hearing;
  • Develop materials for payer engagement initiatives;
  • Support price negotiations with pricing analysis, pricing intelligence and HEOR initiatives;
  • Manage regional and local hurdles and opportunities with Avapritinib and support field teams;
  • Develop and execute the PR/communication plan aligned with brand strategy;
  • Analyze and assess Governmental regulations on national and local level with impact for BPM and develop recommendations to strengthen BPM business;
  • Engage with patient organizations and present BPM as partner in systemic mastocytosis.
Desired Qualifications
  • Ability to lead PMA initiatives and work as part of a team under uncertainty with a “can do” attitude
  • Ability to prioritize and drive for results with an emphasis on quality.
  • Ability to analyze diverse sets of complex information and distill into recommended strategy
  • Computer skills (MS Office programs)
  • Fluency in German and English, both oral and written
  • Effective communication skills at all levels both internally and externally
  • In-depth understanding of health insurance systems such as reimbursement pathways, HTA and contracting opportunities

Blueprint Medicines develops and commercializes kinase inhibitors for cancer and other diseases. Its lead product, Ayvakit (avapritinib), blocks enzymes that drive tumor growth in gastrointestinal stromal tumors with PDGFRA exon 18 mutations. The company also has a pipeline of other kinase inhibitors in clinical development for lung, breast, and blood cancers, plus preclinical programs in immunology and rare diseases. By performing discovery, development, and commercialization in-house, it aims to bring targeted therapies to patients with unmet medical needs and expand its global oncology portfolio.

Company Size

501-1,000

Company Stage

IPO

Headquarters

Cambridge, Massachusetts

Founded

2011

Simplify Jobs

Simplify's Take

What believers are saying

  • Sanofi $9.1B acquisition on June 2, 2025, boosts immunology portfolio and resources.
  • AI and machine learning enhance drug discovery productivity since recent integration.
  • Targeted protein degradation expansion via 2022 VantAI collaboration diversifies pipeline.

What critics are saying

  • Sanofi integration disrupts sales force, eroding Ayvakit market share in 12-18 months.
  • FDA black box warnings for Ayvakit hemorrhage drop prescriptions 20-30% in 6-12 months.
  • Generic avapritinib from Dr. Reddy's captures 40% GIST market by 2028.

What makes Blueprint Medicines unique

  • Ayvakit is the only FDA-approved treatment targeting PDGFRA D842V mutations in GIST.
  • PIONEER four-year data confirm AYVAKIT's sustained efficacy in indolent systemic mastocytosis.
  • BLU-808 shows wide therapeutic window as first-in-class oral wild-type KIT inhibitor.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

401(k) Retirement Plan

401(k) Company Match

Unlimited Paid Time Off

Commuter Benefits

Mental Health Support

Employee Stock Purchase Plan

Parental Leave

Growth & Insights and Company News

Headcount

6 month growth

2%

1 year growth

5%

2 year growth

3%
Fusacq
Jun 2nd, 2025
Sanofi Acquires Blueprint Medicines Biotech

Sanofi has acquired the American biotech company Blueprint Medicines, which specializes in systemic mastocytosis, a rare disease characterized by abnormal activation or proliferation of mast cells in tissues, most commonly the skin and bone marrow.

Google
Jun 2nd, 2025
Sanofi Acquires Blueprint for $9.1B

Sanofi is set to acquire Blueprint Medicines for an equity value of $9.1 billion, according to Bloomberg.

Investors Hangout
Jun 2nd, 2025
Sanofi Acquires Blueprint for $9.1B

Sanofi is acquiring Blueprint Medicines for approximately $9.1 billion, enhancing its immunology portfolio. This acquisition includes Ayvakit, the only FDA-approved treatment for systemic mastocytosis, and promising therapies like elenestinib and BLU-808. Sanofi will finance the deal with cash and new debt, expecting it to boost gross margin and operating income post-2026. The merger aligns with Sanofi's strategy to lead in immunology and address rare diseases.

The Gazette
Jun 2nd, 2025
Sanofi to buy US biopharma group Blueprint for up to $9.5 billion

PARIS (Reuters) -France's Sanofi has agreed to buy U.S.-based Blueprint Medicines Corporation for up to $9.5 billion to boost its position in rare immunology diseases, in the biggest deal struck by a European healthcare company so far this year, according to LSEG data.

GlobeNewswire
Jun 2nd, 2025
Press Release: Sanofi to acquire Blueprint Medicines, expanding portfolio in rare immunological disease and adding early-stage pipeline in immunology

Sanofi to acquire Blueprint Medicines, expanding portfolio in rare immunological disease and adding early-stage pipeline in immunology Adds fast-growing...

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