Full-Time

Scientist I/II

Hplc MS

Posted on 10/8/2024

Tessera Therapeutics

Tessera Therapeutics

201-500 employees

Develops gene writing technology for genetic medicine

Biotechnology
Healthcare

Mid, Senior

Cambridge, MA, USA

Category
Lab & Research
Life Sciences
Medical Research
Required Skills
Data Analysis
Requirements
  • BS in analytical chemistry, biochemistry, or relevant discipline with 8+ years of relevant experience, or M.S. with 6+ years relevant industry experience, or PhD with 1+ years industry experience.
  • The application of a diverse set of analytical assays, with strong background in LC-MS (required) and HPLC.
  • RNA or Oligonucleotide analytical chemistry and biophysical techniques (required), preferably in biopharmaceutically relevant systems.
  • Analyzing and interpreting written material, in various forms including tables and spreadsheets, as well as quantitative and qualitative data.
  • Writing clear and concise reports and memos.
  • A high level of personal and spatial organization.
  • Strong interpersonal and communication skills.
  • A learning and betterment mindset.
Responsibilities
  • Advancing existing and establishing new methods using mass spectrometry, HPLC and electrophoretic methods to characterize RNA molecules (oligos and/or mRNA).
  • Representing the Analytical Development team in cross-functional meetings, presenting results and providing scientific input as needed.
  • Participating in in-depth investigations, including orthogonal method evaluation, understanding RNA and oligonucleotide stability, and characterizing impurities in a CMC setting.
  • Exploring new technology and software to strengthen and streamline RNA and oligonucleotide characterization workflows.
  • Maintaining external awareness of advances in the field through keeping updated on relevant publications, attending conferences and workshops.
  • Effectively collaborating within the Analytical team and with other functional teams.
  • Using scientific and technical expertise for instrument maintenance and troubleshooting.
  • Training and mentoring junior scientists as needed.
  • Performing assays, analyzing, interpreting, and reporting results in appropriate format (ELN, analytical reports, and presentations).
  • Performing additional duties and responsibilities as required.

Tessera Therapeutics focuses on genetic medicine, specifically through a technology called Gene Writing, which enables precise modifications to the human genome. This technology allows for permanent changes to genetic material in any cell, aiming to cure diseases at their source. Tessera's Gene Writing can perform both small and large genetic alterations, making it applicable to a wide range of genetic disorders. The company primarily serves research institutions, pharmaceutical companies, and healthcare providers seeking to develop new treatments for genetic diseases. Unlike its competitors, Tessera Therapeutics emphasizes the versatility of its Gene Writing platform, which can address previously untreatable conditions. The company's goal is to advance the development of its technology to ultimately cure diseases by rewriting the genetic code.

Company Stage

Series C

Total Funding

$518.2M

Headquarters

Cambridge, Massachusetts

Founded

2018

Growth & Insights
Headcount

6 month growth

-5%

1 year growth

-9%

2 year growth

14%
Simplify Jobs

Simplify's Take

What believers are saying

  • Tessera secured $300 million in Series C funding in April 2022.
  • Partnership with Gates Foundation supports in vivo treatment for sickle cell disease.
  • Growing interest in RNA therapies aligns with Tessera's platform development.

What critics are saying

  • Competition from CRISPR-based technologies may challenge Tessera's market position.
  • High development costs could hinder Tessera's market entry and pricing.
  • Regulatory challenges may delay Tessera's product development timeline.

What makes Tessera Therapeutics unique

  • Tessera Therapeutics is pioneering Gene Writing, a novel approach in genetic medicine.
  • Gene Writing allows precise genome alterations, surpassing traditional gene editing limitations.
  • Tessera's technology offers potential cures for genetic diseases at their source.

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