Senior Director

Pharmacology & DMPK

Posted on 6/6/2024

Prime Medicine

Prime Medicine

201-500 employees

Develops next-generation gene editing technology



Cambridge, MA, USA

  • Advanced degree such as M.S. or Ph.D. in biological sciences
  • 10+ years of relevant experience in toxicology, pharmacology, or related discipline
  • Experience designing PK/PD studies including large animal studies
  • Experience building and managing collaborations with CROs, consultants, pharmaceutical partners, and other organizations
  • Ability to manage multiple therapeutic programs in parallel and prioritize according to company needs
  • Strong appreciation for research with a focus on product development and preclinical studies
  • Proven track record of strategic thinking and tactical implementation
  • Comfortable in an entrepreneurial and fast-paced environment
  • Lead Pharmacology, BA, and DMPK groups
  • Accountable for the design, execution, analysis, and interpretation of pharmacology, PK/PD, mechanistic, and safety studies
  • Provide expertise at all stages of discovery and nonclinical development
  • Balance internal infrastructure and capabilities vs. outsourcing
  • Lead external collaborations on large animal studies
  • Partner with Nonclinical development for integration of findings with clinical programs
  • Support Tech Ops in problem-solving issues with drug substance/drug product
  • Ensure high-quality review of study documents
  • Represent Pharmacology during interactions with Regulatory Agencies
  • Foster a culture of transparency and progress tracking
  • Manage conflicting priorities and seek viable solutions
  • Provide guidance on business development opportunities

Prime Medicine, Inc. is a pioneering force in the field of genetic disease treatment through its development of Prime Editing technology. This cutting-edge tool aims to correct faulty DNA sequences by replacing them directly in the genome, targeting about 90% of known genetic mutations associated with diseases. Working at this company provides an opportunity to be at the forefront of genetic research, contributing to potentially transformative treatments that could have far-reaching implications for health and medicine.

Company Stage


Total Funding



Cambridge, Massachusetts



Growth & Insights

6 month growth


1 year growth


2 year growth