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Full-Time

US: Associate Director

Viral Vector Sciences

Confirmed live in the last 24 hours

Legend Biotech

Legend Biotech

1,001-5,000 employees

Develops and commercializes cell therapies

Hardware
Biotechnology

Senior, Expert

Somerset County, NJ, USA

Category
Bioinformatics
Computational Biology
Genomics
Public Health
Biology Lab & Research
Biology & Biotech
Required Skills
Data Analysis
Requirements
  • BS/MS/Ph.D. (or relevant experience) in cell biology, molecular biology, immunology, virology, biomedical engineering or other related sciences preferred
  • 8+ years of experience in viral vector development, production, and analytics
  • Understanding of molecular biology, viral vectors, and viral vector-based assays
  • Expertise in viral vector production (lentiviral, retroviral, or adeno-associated virus) and technology transfer
  • Understanding of plasmid production and testing is a plus
  • Experience in CDMO evaluation and working with external partners
  • Understanding of health authority regulations related to viral vectors
  • Facilitating a multifunctional and multicultural network
  • Knowledge of cGLP/cGMP guidelines
  • Detail-oriented, excellent organizational skills with expertise in problem solving and solid decision-making abilities
  • Strong written and verbal communication skills are essential
  • Ability to operate independently and in a team environment
  • English/Mandarin preferred
Responsibilities
  • Oversee production and testing of lentivirus, retrovirus, and/or AAV at the research, process development or GMP production scale for use in clinical cell and gene therapy project activities
  • Support the evaluation of new CDMO technical capabilities, assist in testing and technical changes, and provide support with CDMOs for execution of development and early clinical project activities
  • Responsible for technical and organizational leadership in tech transfer of a commercial vector; in collaboration with tech transfer project manager, drive, and tack document transfer
  • Responsible for designing the viral vector process and analytical tech transfer strategy and monitoring timelines
  • Collaborate with quality to ensure GMP practices are followed by external partners and implement appropriate controls
  • Conduct technical discussions & meetings with internal and external stakeholders and facilitate implementation of new viral vector technologies
  • Troubleshooting viral vector production process and analytical issues of commercial processes, as well as and proactivity identify and mitigate risks and weaknesses
  • Coordinate, author, and review technical documents, protocols, and reports, including providing SME support to regulatory for USA, China and EU regulatory filings
  • Some travel required

Legend Biotech develops and sells cell therapies aimed at treating serious diseases, particularly cancers like hematological malignancies and solid tumors. Their approach is technology agnostic, allowing them to explore various methods to find effective treatments. The company operates in the personalized medicine sector, focusing on discovering, developing, and bringing new therapies to market. They generate revenue through licensing and selling their therapies, including CAR-T therapies, which involve modifying a patient's own cells to combat cancer. Unlike many competitors, Legend Biotech emphasizes transparency with investors, regularly updating them on financial results and business developments. Their goal is to provide effective treatments for hard-to-treat diseases through innovative cell therapy solutions.

Company Stage

IPO

Total Funding

$750.5M

Headquarters

Franklin Township, New Jersey

Founded

2014

Growth & Insights
Headcount

6 month growth

17%

1 year growth

38%

2 year growth

95%
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Simplify's Take

What believers are saying

  • Legend Biotech's recent European Commission approval for CARVYKTI® positions it as a leader in the multiple myeloma treatment market.
  • Strategic partnerships, such as the one with MaxCyte, enhance Legend Biotech's capabilities in cell engineering and expand its technological reach.
  • The company's commitment to transparency and investor relations, demonstrated through regular financial updates, fosters investor confidence and long-term stability.

What critics are saying

  • The competitive landscape in cell therapy and personalized medicine is intense, requiring continuous innovation to maintain market position.
  • Regulatory hurdles and the need for extensive clinical trials can delay the commercialization of new therapies, impacting revenue streams.

What makes Legend Biotech unique

  • Legend Biotech's technology-agnostic approach allows it to explore multiple innovative therapies, unlike competitors who may focus on a single technology.
  • The company's comprehensive business model, from discovery to commercialization, ensures control over the entire treatment lifecycle, providing a competitive edge.
  • Legend Biotech's strong focus on CAR-T therapies, particularly for hematological malignancies and solid tumors, sets it apart in the personalized medicine sector.