Associate Academic Research Scientist

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Description

A Ph.D. Scientist position with a focus on brain pathology and therapeutic efficacy testing of small molecules in epilepsy and Alzheimer’s disease models is available in the laboratory of Dr. Thota Ganesh, Nick Varvel and Ray Dingledine combined laboratory at the Department of Pharmacology and Chemical Biology, Emory University School of Medicine, in Atlanta, Georgia, USA.

The Associate Academic Research Scientist performs a wide range of highly technical and complex research duties and has documented scientific achievements and increasing technical, management, leadership, and professional expertise necessary to advance basic and/or translational research programs.

The successful candidate will play a key role in experimental design, data collection and analysis. He/she will collaboratively work with a multi-disciplinary team of neuroscientists and medicinal chemists to acquire biochemical and histology data from in vitro and in vivo animal models.

KEY RESPONSIBILITIES:

• Demonstrated knowledge of research and experimental platforms for analyzing, design and interpreting results Investigates and recommends potential alternative approaches to improve the quality of results of basic and/or translational research.
• Demonstrates increased responsibility through management of teams and leadership of scientific projects by applying advanced knowledge, skills, and input necessary for protocol development, as well as facilitating in some training aspects of other team members.
• Aids in writing IACUC, IRB, Biosafety and other approval documents.
• Treating rodents with investigational drug candidates for weeks to months and study behavioral deficits, harvesting the blood and brain at the end point for analysis.
• Analysis of brain inflammation and neuropathology by ELISA, Western-blot, qRT-PCR, immuno-histochemistry to study amyloid plaques, soluble amyloids, gliosis and neurodegeneration.
• Oversees quality assurance of research conducted by other team members.
• May assist in grant and other funding applications as necessary and appropriate, or with approval of the responsible faculty director, may have their own research projects and/or have full responsibilities for specific areas of instrumentation or methodology development and user support.
• With the approval of the responsible faculty director, may be principal investigators on funded proposals.
• Performs other responsibilities as required.

MINIMUM QUALIFICATIONS:

• PhD and one year of professional level experience in a technical or research lab.
• Or master's degree and three years of professional level experience in a technical or research lab.
• Or bachelor's degree and five years of professional level experience in a technical or research lab.
• Laboratory experience should be based on area of assignment.
• Internship experience or experience prior to attaining the qualifying degree is not considered eligible work experience for this job classification.

Preferred Qualification:

• Ph.D. in molecular, neurobiology or neuropharmacology with 0-4 year of postdoctoral or scientific research experience in above fields. Additional experience working with transgenic Alzheimer’s rodent models will be an advantage.

• Familiarity with rodent brain/tissue harvesting, surgical procedures, brain sectioning; use of microscope, confocal, cryostat, and PCR machines.
• Experience with cognitive and memory assays on mice or rats, Analysis and trouble shooting in cognitive assays is plus.
• Familiarity with immuno-histochemistry of gliotic markers, ELISA and Western blot techniques.
• Cell culture work, including creation of stable cell lines using vectors/constructs, and testing the novel compounds for potency evaluation.

NOTE: Position tasks are generally required to be performed in-person at an Emory University location.  Remote work from home day options may be granted at department discretion. Emory reserves the right to change remote work status with notice to employee.

Additional Details

Emory is an equal opportunity employer, and qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by state or federal law. Emory University does not discriminate in admissions, educational programs, or employment, including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training. Students, faculty, and staff are assured of participation in university programs and in the use of facilities without such discrimination. Emory University complies with Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veteran's Readjustment Assistance Act, and applicable executive orders, federal and state regulations regarding nondiscrimination, equal opportunity, and affirmative action (for protected veterans and individuals with disabilities). Inquiries regarding this policy should be directed to the Emory University Department of Equity and Civil Rights Compliance, 201 Dowman Drive, Administration Building, Atlanta, GA 30322. Telephone: 404-727-9867 (V) | 404-712-2049 (TDD).

Emory University is committed to ensuring equal access and providing reasonable accommodations to qualified individuals with disabilities upon request. To request this document in an alternate format or to seek a reasonable accommodation, please contact the Department of Accessibility Services at [email protected] or call 404-727-9877 (Voice) | 404-712-2049 (TDD). We kindly ask that requests be made at least seven business days in advance to allow adequate time for coordination.